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Researchers Discover Prenatal Genetic Origins of Childhood Absence Epilepsy

Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium channel mutations disrupt early brain development and predispose children to epilepsy and related cognitive challenges.

6 Apr 2026

Tumors Disable Dendritic Cells by Decreasing Mitochondrial Fitness

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring their energy production can improve immunotherapy.

3 Apr 2026

Molecular Switch AHR Limits Neuron Regeneration and Axon Repair

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

3 Apr 2026

New Gene-Editing Approach Eliminates Painful Crises in Sickle Cell Disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

2 Apr 2026

Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

Nonviral Nanoparticles Show Promise for Safer Gene Delivery Methods

In a demonstration that helps pave the way for gene therapies with fewer side effects, several human cell types were genetically modified with protein nanoparticles designed at University of Michigan Engineering and Michigan Medicine.

1 Apr 2026

Autism-Associated Genes are Largely the Same Across Different Global Ancestries

A new study, co-led by researchers at the Icahn School of Medicine at Mount Sinai and published March 30 in Nature Medicine, demonstrates that genes associated with autism risk are largely the same across people of different ancestries.

31 Mar 2026

Fusion Protein Rewires Brain Development to Trigger Pediatric Cancer

A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital and collaborating institutions reveal in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor.

28 Mar 2026

Researchers Identify the Nuclear Root of Cellular Aging

Some aging indications in human cells arise in the cell nucleus, where the packaged form of DNA changes with age.

27 Mar 2026

The Future of Vision Restoration With ReVision Implant

ReVision Implant is pioneering neuroprosthetic technology to restore vision in blind patients using advanced cortical implants and flexible electrode arrays.

26 Mar 2026

New Skin Atlas Reveals Cellular Diversity Across Body Sites

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body.

26 Mar 2026

New PanNDA Atlas Maps Protein Networks in Neurodegenerative Diseases

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's Research Hospital scientists developed the pan-neurodegeneration atlas (PanNDA).

24 Mar 2026

'Spiderman' Cells Trap Viral Genomes With Sticky Protein Webs

Scientists have identified a cell defense mechanism that mimics Spiderman shooting his web to ensnare enemies.

18 Mar 2026

Study Reveals Microbiome Role in Protecting the Colon From Tissue Injury

The gut microbiome-the trillions of bacteria and other microbes that inhabit the gastrointestinal tract-drives a process vital for protecting the colon against tissue injury, according to the findings of a study co-led by Cedars-Sinai Health Sciences University investigators.

11 Mar 2026

Whole-Cell Simulation Recreates Molecular Dynamics of Minimal Living Cell

By simulating the life cycle of a minimal bacterial cell - from DNA replication to protein translation to metabolism and cell division - scientists have opened a new frontier of computer vision into the essential processes of life.

10 Mar 2026

Research Shows Successful Recovery of Antigen-Specific T Cells in Mouse Models

Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body's immune responses painlessly from the skin. The device detects inflammatory signals within minutes and collects specialized immune cells within hours without the need for blood draws or surgical biopsies.

3 Mar 2026

Scientists Discover Unique Chromosome Reorganization in Developing Germ Cells

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic precursors of these cells uniquely reshape the 3D organization of their genetic material.

23 Feb 2026

Small RNAs in the Sperm Guide the Earliest Stages of Embryonic Development

Mounting evidence from research on nematodes to mice indicate that a father's environment, such as what he eats or if he is exposed to stress or toxicants, can lead to metabolic and behavioral disorders in his offspring.

20 Feb 2026

New Antibodies Prevent EBV Infection in Humanized Mouse Models

Fred Hutch Cancer Center scientists reached a crucial milestone in blocking Epstein Barr virus (EBV), a pathogen estimated to infect 95% of the global population that is linked to multiple types of cancer, neurodegenerative diseases and other chronic health conditions.

18 Feb 2026

How a Single List Is Changing Visibility for Women in Science

Cristina Legido-Quigley shares insights on lipidomics and Alzheimer's disease, focusing on metabolic factors and the importance of women's visibility in STEM.

11 Feb 2026