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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Unraveling the Mysteries of the Barr Body and Aging

Aging in female mice shows increased gene activity on the second X chromosome, offering insights into cardiovascular disease and neurodegenerative disorders.

28 May 2025

Study Reveals How APOE Isoforms Impact Brain Microglia

A study reveals how APOE isoforms influence microglial activity in Alzheimer's, highlighting the need for targeted interventions based on genetic risk factors.

28 May 2025

Cobraa: A Coalescence-Based Model Infers a Structured Ancestry Shared by Modern-Day Humans

The Cobraa model offers insights into human evolution, detailing ancestral population dynamics and genetic admixture events over the last 1.5 million years.

28 May 2025

Epigenome Editing: Enhancing Endonuclease Protein Design for In Vivo Applications

Researchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome editing using AAV delivery, offering a powerful tool for gene regulation without DNA breaks.

28 May 2025

Extracellular RNA Profiling Recommendations: Results From exRNAQC, a Comprehensive Assessment of Pre-Analytical Factors for Quality Control

A large-scale study (exRNAQC) outlines how blood tube type, RNA purification method, and processing time influence exRNA profiles. Results support new guidelines for researchers and diagnostic product developers working on RNA-based biomarkers.

28 May 2025

Cold Adaptation in Rice Offers New Insights into Evolution

Chinese researchers recently discovered molecular evidence supporting Lamarckism, a long-debated theory from the early 19th century that suggests acquired traits can be inherited.

27 May 2025

Study Shows How Age-Related Metabolic Decline Impairs the Efficacy of CAR-T Cell Therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

26 May 2025

Study Reveals How Genetic Differences in TRIO Affect Neurodevelopment

Researchers have identified how variations in a gene called TRIO can influence brain functions and result in distinct neurodevelopmental diseases.

24 May 2025

RNA Editing and Transcriptional Switching Shape Fungal Antiviral Response

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely unknown, especially in the case of fungus-virus pathogen systems.

24 May 2025

Study Reveals How Introns Multiply and Move Across Genomes

DNA is the genetic code that provides the biological instructions for every living species, but not every bit of DNA helps the species survive. Some pieces of DNA are more like parasites, along for the ride and their own survival.

24 May 2025

Reversible DNA Modification Controls Replication and Gene Activity

Study uncovers ADP-ribosylation's role in Mycobacterium tuberculosis, showing how DNA modification controls replication and gene expression for survival.

23 May 2025

Waters Acquires Halo Labs, Expanding Biological Analysis Portfolio

Waters Corporation today announced that it has acquired Halo Labs™, an innovator of specialized imaging technologies to detect, identify, and count interfering materials (particles) in therapeutic products, such as cell, protein, and gene therapies.

23 May 2025

Study Reveals Epigenetic Clues Behind Autism Development

Autism spectrum disorder (ASD) is a condition affecting the brain's development and often affects the ability of a person to perceive sensory information and social cues and socialize with others.

22 May 2025

Study Reveals Genetic Predisposition to Long COVID Near Lung-Related Gene

A global group of scientists has discovered a genetic connection to persistent COVID-19 symptoms.

22 May 2025

New CRISPR Technology for Precise RNA Delivery in Neurons

Proteins produced by RNA segments can aid in the repair of damaged neurons in human bodies.

22 May 2025

Unraveling the Co-Evolution of Human Height and Basal Metabolic Rate

Taller stature and a higher basal metabolic rate are two characteristics that distinguish modern humans from non-human primates. A genetic variant that helped these traits co-evolve was discovered by researchers and published in Cell Genomics.

22 May 2025

Compression Drives Aggressive Behavior in Liver Cancer Cells

Yale researchers are providing new insights into how physical forces, such as cells being compressed in physically restrictive environments, play key roles in cancer progression.

21 May 2025

Geisinger Scientists Uncover Genetic Basis for Sex-Based Height Variation

Geisinger's study reveals Y chromosome genes significantly influence height differences between sexes, highlighting genetic factors beyond hormones.

21 May 2025

Autophagy: A Double-Edged Sword in Cancer and Protein Conformational Disorders

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its potential as a therapeutic target and the challenges of tipping the balance between protection and harm.

20 May 2025

Environmental Nanoplastics Linked to Increased Foodborne Virus Severity

There are nanoplastics everywhere. These particles are found in water, food, and bodies; they are so small that they can build up on bacteria and be absorbed by plant roots.

20 May 2025