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AI Uncovers Rare Mutations with Major Impact on Heart Health

Researchers at the Icahn School of Medicine at Mount Sinai have discovered unusual coding variants in 17 genes that provide insight into the molecular causes of coronary artery disease (CAD), the world's leading cause of morbidity and mortality.

12 Jun 2024

AMPLON Simplifies DNA Amplification for Diverse Medical Applications

A team of researchers from Case Western Reserve University School of Medicine has created a novel method for target DNA sequence amplification, testing, and analysis.

6 Jun 2024

High-Accuracy DNA Methylation Clocks Illuminate Age-Related Changes in Primate Ovaries

The ovary is an essential organ for female fertility, and its age-dependent decline in function is a major cause of infertility.

5 Jun 2024

Brain Organoids Emerge as Powerful Tool for Drug Discovery in Mitochondrial Disease

The use of brain organoids in screening for drugs against mitochondrial diseases, which have hitherto presented challenges in treatment.

4 Jun 2024

KIT Researchers Uncover New Cell Type Responsible for Vascular Growth

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

Nucleus Genomics Introduces DNA Analysis Product for Personalized Medicine

Nucleus Genomics, the next-generation genetic testing and analysis company, today announced the launch of its DNA analysis product to bring the benefits of personalized medicine to everyone.

26 Mar 2024

Study Reveals Unique Bacterial Fingerprints and Their Impact on Health

The trillions of bacteria that call your body home -; collectively known as the microbiome -; appear to be unique to you, like a fingerprint.

13 Mar 2024

Unlocking the Potential of Microbiome-Based Cancer Therapies

The microbiome can identify patients with rare gynecological cancers, biliary tract cancers, and melanoma who will benefit from combination immunotherapy for various cancer types.

4 Mar 2024

Safer and More Effective Cell Therapy for Spinal Cord Injuries

For patients with spinal cord injuries, a small gadget developed by researchers at MIT and the Singapore-MIT Alliance for Research and Technology may help to increase the efficacy and safety of cell therapy treatments.

8 Feb 2024

Penn State Professor Receives NIH Grant to Study How Microbial Communities Impact Human Health

The bacteria and microorganisms that live within the human body -; the microbiota -; can impact human health, disease risk and even how the body absorbs medications, but the details of these processes are unclear.

6 Feb 2024

RNA-Seq Unveils Molecular Subtypes for Tailored Pediatric B-ALL Treatment

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

31 Jan 2024

Formulatrix® and Olink® Announce Collaboration to Deliver Automated Proteomics Research Solutions to Enable Protein Detection with Exceptional Precision and Speed

Formulatrix, a leader in innovative automated liquid handling technologies, announced a multi-year collaboration and supply agreement to advance the automation of Olink’s PEA (Proximity Extension Assay) technology, including the Target 96, Target 48, Flex, and Explore workflows.

From FORMULATRIX 31 Jan 2024

Cholangiocarcinoma: New Organ-On-Chip Aims at Accelerating Research and Personalized Medicine

It is only a few centimeters in size and can be held between two fingers, but in the micro-channels carved inside it, it’s hidden a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment.

23 Jan 2024

Could Bio-Printing Be the Future of Affordable and Personalized Healthcare?

Healthcare costs are increasing at record rates around the world, at a global average of 10% from 2022 to 2023, according to the 2023 Global Medical Trends Survey.

16 Jan 2024

Innovative Machine Learning Tool Predicts Functional Consequences of Genetic Variants

In a recent research, scientists from the Icahn School of Medicine at Mount Sinai unveiled LoGoFunc, an innovative computational tool designed to forecast both pathogenic gain- and loss-of-function variants throughout the genome.

15 Dec 2023

Revolutionizing Peptide Sequencing with Machine Learning for Personalized Medicine

Scientists are employing machine learning to examine the structure of unfamiliar cells, potentially opening the door to improved personalized medicine for addressing cancer and other serious ailments.

29 Nov 2023

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

Software Tool Paves the Way for Safer CRISPR Genome Editing

Researchers have developed a groundbreaking software tool known as DANGER analysis, offering a solution for safer and more precise genome editing.

23 Oct 2023

Do Host Social Interactions Influence Gut Bacteria Evolution?

A recent study demonstrates how host social interactions can have a significant influence on the development of gut bacteria in the gut microbiome. The study, carried out by a group of researchers from Instituto Gulbenkian de Ciência, sought to investigate the impact of host-to-host bacterial transmission on Escherichia coli (E. coli) evolution in mammalian guts.

3 Aug 2023

New Nanopore Technology Can Identify Single-Molecule Protein Variations

A group of researchers guided by the University of Oxford has made significant progress in detecting changes in protein structures. The method, which was published in Nature Nanotechnology, uses novel nanopore technology to detect structural variations at the single-molecule level, even deep within long protein chains.

2 Aug 2023