Signaling Pathway News and Research

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DNA Aptamer Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

12 Oct 2023

Macrophages Play Central Role in Intestinal Cell Renewal

A research team comprising members from MedUni Vienna and the FWF-sponsored Special Research Area SFB F83 Immunometabolism has made a groundbreaking discovery, highlighting the central role of macrophages in the regeneration of intestinal cells.

11 Oct 2023

Researchers Target Pancreatic Cancer’s Metabolic Switch

In a recent study, a novel combination of treatments was discovered to effectively reduce the growth of pancreatic cancer in mice by inhibiting cancer cells from seeking fuel sources.

11 Oct 2023

Regulator Gene for Intestinal Stem Cells Discovered

When a cell dies, a new one has to be formed in its place. This is a regular occurrence in the intestines, where cells are especially exposed to harmful effects.

9 Oct 2023

Unraveling the Link Between Chromosomal Instability and Cancer Spread

Chromosomal instability is a phenomenon marked by rapid alterations in the count and configuration of chromosomes during cell division. This occurrence is prevalent in solid tumors and is closely associated with the aggressive dissemination of cancer, known as metastasis.

27 Sep 2023

The Intriguing Phenomenon of Cellular Reprogramming

A fascinating phenomenon of cellular reprogramming in developed adult organs has been revealed by researchers, providing insight into a brand-new process of adaptive development.

12 Sep 2023

NSL Complex Regulates Intraciliary Transport Genes in Multiple Cell Types

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown in both fruit flies and mammals to regulate the expression of thousands of genes. Abrogation of the NSL genes causes the organism to die, which gives rise to the complex’s unusual name.

28 Aug 2023

Unique Molecular Structure Has Effects on Age-Related Diseases

The mitochondria, sometimes known as the “powerhouses of the cell,” are widely recognized for their function as energy producers, but these organelles are also essential for preserving general health.

8 Aug 2023

Revealing a Novel Signaling Pathway Fostering Aging-Related Chronic Metabolic Disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

4 Aug 2023

Potential Strategies for Slowing Cognitive Deterioration in Age-Associated Neurodegenerative Conditions

As we age, our bodies undergo various changes that can impact our overall health and make us more susceptible to diseases.

3 Aug 2023

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

Researchers Perform a Study on How Cells Communicate With Each Other

Like us, cells communicate. Well, in their own special way. Using waves as their common language, cells tell one another where and when to move.

20 Jul 2023

New Tool Maps Cellular Stress Memory

When does that seasonal tan turn into a melanoma risk? When might those extra pounds cause diabetes? Could severe head injuries cause Alzheimer’s to develop? In the grand scheme of things, genetics, lifestyle, and age are risk factors, with the solutions frequently appearing only after the unfortunate diagnoses.

20 Jul 2023