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New technology generates immune response by delivering antigens to APCs in the spleen

Red blood cells do more than shuttle oxygen from our lungs to our organs: they also help the body fight off infections by capturing pathogens on their surfaces, neutralizing them, and presenting them to immune cells in the spleen and liver.

14 Jul 2020

Fully automated chip can quickly and reliably determine patients’ blood type

Blood transfusion, if performed promptly, is a potentially life-saving intervention for someone losing a lot of blood. However, blood comes in several types, some of which are incompatible with others.

14 Jul 2020

New mutation in common flu subtype helps evade immune response

Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

13 Jul 2020

Super-resolution microscopy methods reveal the smallest cell structures

Theoretically, high-resolution microscopy should make it possible to capture cell structures that have a resolution of a few nanometers.

8 Jul 2020

Scientists discover role of surface diffusion in protein transport

Many of the most promising medicines under development are proteins, often antibodies, to help patients fight disease. These proteins must be purified as part of the manufacturing process -- a task that can be tricky and result in costly waste.

8 Jul 2020

New device can help test potential drug candidates for COVID-19

Scientists have created a human cell “membrane on a chip” that enables tracking of the interaction of drugs and infectious agents with the human cells.

6 Jul 2020

Researchers identify protective antibodies for rare, polio-like disease in children

Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

6 Jul 2020

Study highlights the role of hematopoietic immune cells in gene regulation

More often, the human body is viewed as a “machine” containing specialized components: immune cells protect against pathogens, organs contribute physiological functions, and soft tissue and bones give structure.

6 Jul 2020

Researchers discover protein involved in protecting B cells

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

2 Jul 2020

Even the sickest COVID-19 patients produce T cells to fight back the virus

A new study from researchers at La Jolla Institute for Immunology and Erasmus University Medical Center shows that even the sickest COVID-19 patients produce T cells that help fight the virus.

1 Jul 2020

Engineered T-cells attack solid-tumor cancer cells from humans and mice

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia.

1 Jul 2020

Study provides roadmap for developing effective vaccine against Staphylococcal infections

Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments.

1 Jul 2020

Sanford Burnham Prebys announces research agreement with Lilly to characterize COVID-19 antibodies

Sanford Burnham Prebys Medical Discovery Institute today announced a research agreement with Eli Lilly and Company (Lilly) to characterize Lilly's next-generation anti-SARS-CoV-2 antibodies.

30 Jun 2020

Chemically engineered peptides show promise to block viruses

Scientists from Rensselaer Polytechnic Institute have designed and developed chemically engineered peptides that may prove useful to fight some of the most prevalent human health challenges.

29 Jun 2020

C. difficile hijacks the wound healing system to cause serious and persistent disease

Monash University researchers have discovered that the devastating bacterial superbug Clostridioides difficile hijacks the human wound healing system in order to cause serious and persistent disease, opening up the development of new therapies to treat the disease.

26 Jun 2020

Subtypes in alzheimer's disease may be linked to tau protein modifications

A new study reveals a possible biological reason that Alzheimer's Disease (AD) progresses at different rates in different patients.

25 Jun 2020

Experts identify steps to expand, improve SARS-CoV-2 serology tests

More than 300 scientists and clinicians from the federal government, industry and academia published a report of their conclusions and recommendations on COVID-19 serology studies online in Immunity.

24 Jun 2020

Antibody and RNA testing can help track SARS-CoV-2 virus

SARS-CoV-2 is usually tracked by two types of tests, reverse transcriptase PCR (rt-PCR) and antibody tests.

23 Jun 2020

White Paper: Separation and characterization of viruses and antibodies

Postnova Analytics have published an informative new white paper that details how multi-detector Asymmetrical Field Flow Fractionation (AF4) and Electrical AF4 (EAF4) techniques are transforming the separation and characterization of viruses and antibodies.

From Postnova Analytics 23 Jun 2020

New study shows how a protein works as 'master regulator' in the immune system

Scientists at the La Jolla Institute for Immunology have discovered a potential new way to better fight a range of infectious diseases, cancers and even autoimmune diseases.

22 Jun 2020