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Study shows thymoquinone compound selectively kills prostate cancer cells

According to a new study reported in the Oncogene journal, the thymoquinone (TQ) compound selectively destroys prostate cancer cells at advanced phases.

9 Oct 2020

Study offers new treatment strategies for HIV

According to a new study, immune cells that can detect residual HIV-infected cells in patients living with HIV and undergoing ART continue to remain active.

8 Oct 2020

Cancer mutations occur in distinct patterns based on 3D structure of the genome

A new study from researchers at The University of Texas MD Anderson Cancer Center has discovered that mutations found in cancers do not accumulate randomly, but are found in distinct patterns that vary based on the three-dimensional organization of the genome in the cell as well as the underlying factors causing the mutations.

6 Oct 2020

Vacuolar Tauopathy: New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.

5 Oct 2020

Epigenetic alterations drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

29 Sep 2020

Cocaine addiction: Impact of genetic mutations elucidated

Cocaine addiction is a chronic disorder with a high rate of relapse for which no effective treatment is currently available.

28 Sep 2020

Researchers identify risk factors for COVID-19 mortality

Scientists have proposed that carriers of two genetic mutations PiS and PiZ face a greater risk for severe illness and even death from COVID-19 disease.

25 Sep 2020

Study may help develop new immunotherapies for different types of tumors

A team of researchers have plotted the genes that enable cancer cells to avoid being destroyed by the immune system.

From University of Toronto 25 Sep 2020

Study identifies genetic mutation linked with fibromuscular dysplasia

Understanding of fibromuscular dysplasia (FMD), a rare blood vessel disease, is making the jump from the laboratory to the clinic with new findings about a genetic variant.

25 Sep 2020

Computational model effectively identifies genetic mutations in breast tumors

Researchers at Lund University in Sweden have developed a computational model which is effective in detecting and identifying genetic mutations in breast tumors. The study, the largest of its kind in the world, includes results from over 3 200 patients with breast cancer.

25 Sep 2020

Researchers discover novel genes for human deafness in Israeli families

Until now, seven genes were known to be involved in hearing loss in Israel's Jewish population. A new study led by Zippora Brownstein, PhD, and Prof. Karen Avraham from the Sackler Faculty of Medicine at Tel Aviv University has found that 32 genes are responsible for inherited hearing loss in Israeli Jewish families.

24 Sep 2020

UB biophysicist receives $2 million NIH grant to explore protein-RNA droplets

Inside human cells, proteins and RNA can cluster together to form spherical droplets that play vital roles in cellular processes as well as in certain human diseases.

23 Sep 2020

New insight into how people with retinal degenerative disease can maintain night vision

New insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time has been published today in the open-access eLife journal.

23 Sep 2020

Genetic differences between domesticated and wild chickens linked to epigenetic changes

Some of the genetic differences that have arisen between domesticated chickens and their wild ancestors, the red junglefowl, are linked to epigenetic changes, according to a new study published in Nature Ecology & Evolution.

22 Sep 2020

Human genetics: New insights into our own biology

Who are we? Where did we come from? How did we get here? Throughout the ages, humans have sought answers to these questions, pursuing wisdom through religion, philosophy, and eventually science.

21 Sep 2020

Study pinpoints specific protein involved in the mass production of antibodies

A team of researchers has discovered how a specific protein called JAGN1 plays a crucial role in the production of antibodies.

17 Sep 2020

Epigenetic defects in the human genome cause genetic disorders

A study has demonstrated that epigenetic defects in the human genome are common and occur in an unlimited number of genes that lead to genetic disorders.

17 Sep 2020

Researchers unravel the molecular basis underlying colorectal cancer

A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.

15 Sep 2020

Study pinpoints specific genes that cause ovarian cancer

High-grade serious ovarian carcinoma is the fifth major cause of cancer-associated deaths in women in the United States.

14 Sep 2020

In-depth study of kidney tumors reveals novel markers of response to immunotherapy

Treatments for kidney cancer have improved considerably over the past few decades. In 1988, when Memorial Sloan Kettering oncologist Robert Motzer started researching the disease, the average survival was less than one year.

9 Sep 2020