Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Depletion of stem cells could be a significant factor behind miscarriage

Depletion of a certain type of stem cell in the womb lining during pregnancy could be a significant factor behind miscarriage, according to a study released today in STEM CELLS. The study, by researchers at Warwick Medical School, University of Warwick, Coventry, England, reports on how recurrent pregnancy loss is a result of the loss of decidual precursor cells prior to conception.

26 Mar 2021

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.

24 Mar 2021

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

Study reveals molecular profiles of Parkinson's disease

The second most common neurodegenerative disorder is Parkinson’s disease, but despite this, not much is known about the causes of this condition.

17 Mar 2021

PrecisionTox aims to protect human health from the toxic effects of chemicals

A major research project to shape regulation and policy on chemical safety without the use of animal testing has been launched with the aid of €19.3M funding from the European Commission.

10 Mar 2021

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

9 Mar 2021

Genomics study examines the impact of COVID-19 on care homes

Care homes are at high risk of experiencing outbreaks of COVID-19, the disease caused by SARS-CoV-2. Older people and those affected by heart disease, respiratory disease and type 2 diabetes - all of which increase with age - are at greatest risk of severe disease and even death, making the care home population especially vulnerable.

4 Mar 2021

New software tool enables swift analysis of datasets generated from single-cell sequencing

A new software tool allows researchers to quickly query datasets generated from single-cell sequencing. Users can identify which cell types any combination of genes are active in.

4 Mar 2021

New algorithm identifies 'escaping' cells in single-cell CRISPR screens

A team of researchers from New York has developed a new computational tool to help understand the function and regulation of human genes.

3 Mar 2021

New computational tool reveals the function and regulation of human genes

A new computational tool has been developed by a research team from New York to figure out the regulation and function of human genes.

2 Mar 2021

UChicago-based team shares new details about Genomic Data Commons

The National Cancer Institute's Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with more than 3.3 petabytes of data from more than 65 projects and over 84,000 anonymized patient cases, serving more than 50,000 unique users each month.

1 Mar 2021

Researchers identify gene variant associated with childhood asthma

Researchers at Henry Ford Health System, as part of a national asthma collaborative, have identified a gene variant associated with childhood asthma that underscores the importance of including diverse patient populations in research studies.

1 Mar 2021

Researchers sequence 64 human genomes at high resolution

After the successful conclusion of the “Human Genome Project”, an international research team has sequenced a total of 64 human genomes at high resolution.

26 Feb 2021

Setting new standards for the exchange of human omics data

Genomics, transcriptomics, proteomics, metabolomics, and others... The "omics" technologies keep revolutionizing medicine and biomedical sciences.

25 Feb 2021

Interbacterial toxins may contribute to bacterial genetic diversity

A toxin produced by bacteria as a defense mechanism causes mutations in target bacteria that could help them survive, according to a study published today in eLife.

24 Feb 2021

Study highlights the effect of climate change on microbial interactions

A study investigates the effects of climate warming on the complexity of the microbial network, offering important insights into ecosystem management.

23 Feb 2021

A functional test to measure the effect of inherited gene variants in breast and ovarian cancer

Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS).

22 Feb 2021

Color morphs speak of the coral's resilience to high temperatures

Anyone who visits the Great Barrier Reef in Australia, Southeast Asia's coral triangle, or the reefs of Central America, will surely speak of how stunning and vibrant these environments are.

22 Feb 2021

Advanced explainable AI to solve regulatory instructions encoded in DNA

Researchers at the Stowers Institute for Medical Research, in collaboration with colleagues at Stanford University and Technical University of Munich have developed advanced explainable artificial intelligence (AI) in a technical tour de force to decipher regulatory instructions encoded in DNA.

19 Feb 2021

Testing for inherited genes can help understand future cancer risk in pediatric patients

Because cancers in children are rare, many details about their biology remain unknown. In the field of cancer genetics, there's a limited understanding of how inherited genetic changes may contribute to the formation and growth of tumors.

17 Feb 2021