Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Generative AI Enhances Spatial Gene Expression Analysis in Tissue Samples

Spatial transcriptomics is an advanced technique that analyzes gene expression within tissue sections, such as those from the heart, skin, or liver. These analyses offer valuable insights into how spatial organization influences cellular functions across various biological contexts and diseases.

13 Mar 2025

Molecular Intelligence Simplifies Cryo-EM Data Analysis with AI

Scientists from Purdue University’s College of Science and the Rosen Center for Advanced Computing have established Molecular Intelligence, a software company dedicated to assisting researchers in determining the 3D structures of biomolecules captured through cryogenic-electron microscopy (cryo-EM).

13 Mar 2025

Researchers Create 'Colocatome' to Study Tumor Cell Interactions

Even cells experience peer pressure. Scientists have long studied the ins and outs of cancer cells to learn more about the disease, but they're increasingly finding that noncancerous cells near the cancer cells exert a powerful influence over a tumor's trajectory.

13 Mar 2025

Study Explores the Physiological Role of Nwd1 Gene in MASH Pathogenesis

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

12 Mar 2025

Machine Learning Addresses Ancestral Diversity in Disease Prediction

To ensure that medical genetic research better represents and benefits people from all backgrounds, researchers at the University of Florida are filling a crucial gap in the field.

11 Mar 2025

Unveiling the Shapeshifting Mechanisms of Metamorphic Proteins

The “shapeshifters” of bacterial, animal, and human cells are metamorphic proteins. Their capacity to rapidly transition between two distinct shapes allows them to perform a variety of tasks and adjust to shifting conditions.

11 Mar 2025

‘Rescue’ Mutations Protect Liver From Damage in Patients With Genetic Disorder

Acquired DNA mutations found in the SERPINA1 gene can protect liver cells from damage in patients with alpha-1 antitrypsin deficiency, new research shows.

11 Mar 2025

Circular RNA's Transformative Role in Tumor Biology and Treatment

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

10 Mar 2025

Investigating Ubiquitination's Role in Cancer Stem Cell Regulation

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance.

10 Mar 2025

$30 Million Grant Supports AI-Powered Antibody Therapy Development

An ambitious project led by Vanderbilt University Medical Center investigators aims to use artificial intelligence technologies to generate antibody therapies against any antigen target of interest.

10 Mar 2025

Structural Insights into uMtCK Offer New Pathways for Targeting Cancer Energy Mechanisms

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells hijack various cellular functions to find and exploit energy and other resources, including a group of enzymes that help normal cells maintain a balance of energy.

8 Mar 2025

Tumour-on-Chip Model Supports Preclinical Drug Development on Pancreatic Cancer

The biotech company Dynamic42, a specialist in organ-on-chip technology, has made a significant advance in pancreatic cancer drug research in collaboration with the research team of Prof. Dr. Nicole Teusch at the Institute of Pharmaceutical Biology and Biotechnology at Heinrich Heine University Düsseldorf.

7 Mar 2025

Tumor Cell Adhesion Could Help Predict Breast Cancer Spread

By assessing how "sticky" tumor cells are, researchers at the University of California San Diego have found a potential way to predict whether a patient's early-stage breast cancer is likely to spread.

6 Mar 2025

Dual Antibodies Found to Combat All SARS-CoV-2 Variants

A Stanford-led team has found two antibodies that can work together to defeat all SARS-CoV-2 variants. More research is needed, but the approach could help in the development of treatments to keep pace with evolving viruses.

6 Mar 2025

Light-Driven Protein Isolation Replaces Affinity Chromatography

Proteins are essential in the life sciences, playing a crucial role in fundamental research, biotechnological applications, and the development and production of pharmaceuticals.

6 Mar 2025

New Insights Into Ageing Revealed

The way in which blood stem cells evolve over a lifespan differs greatly between humans and mice, new research reveals. The findings provide a new understanding of the critical factors that influence tissue ageing.

5 Mar 2025

New Genetic Clues Could Explain Prostate Cancer’s Aggressive Progression

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.

4 Mar 2025

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code.

4 Mar 2025

New Tool to Map the Origins and Journeys of Cells in Development and Disease

A new computational tool allows researchers to understand how the diverse cell types of the human body are made during development, and how diseases progress over time at the cellular level.

4 Mar 2025

New AI-Based Device Makes Flow Cytometry Affordable and Accessible

A team of researchers at the George R. Brown School of Engineering and Computing at Rice University has developed an innovative artificial intelligence (AI)-enabled, low-cost device that will make flow cytometry ⎯ a technique used to analyze cells or particles in a fluid using a laser beam ⎯ affordable and accessible.

3 Mar 2025