Diabetes News and Research

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Diabetes is a disorder of metabolism—the way the body uses digested food for growth and energy. Most of the food people eat is broken down into glucose, the form of sugar in the blood. Glucose is the main source of fuel for the body.

Low Extracellular Sodium Concentrations Can Suppress mRNA Expression in Brain Cells

Brain and mental problems can result from chronic hyponatremia, a disorder marked by low blood salt levels.

19 Sep 2024

One-Third of Antibody Drugs Show Unintended Target Binding

Integral Molecular, a leader in antibody discovery and characterization, has published new research in the journal mAbs, revealing that as many as one-third of antibody-based drugs exhibit nonspecific binding to unintended targets.

18 Sep 2024

A Powerful New Tool for Biomedical Research

Scientists at Weill Cornell Medicine in Qatar (WCM-Q) have built a comprehensive molecular map of the human body and its complicated physiological processes by analyzing thousands of molecules found in 391 volunteers' blood, urine, and saliva samples.

12 Sep 2024

Crystal Structure of i-Motif DNA Opens Doors for Targeted Drug Design

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.

9 Sep 2024

SGLT-2 Inhibitors May Lower Dementia Risk in Type 2 Diabetes Patients, Study Finds

A study reveals SGLT-2 inhibitors significantly reduce dementia risk in type 2 diabetes patients, with effects strengthening over longer treatment durations.

9 Sep 2024

From Bone Regeneration to Heart Repair: Stem Cell Transplantation Paves the Way for New Medical Frontiers

Stem cell transplantation offers promising solutions for tissue regeneration and age-related degeneration, despite challenges in safety and production costs.

9 Sep 2024

Beta Cells Alone Can Maintain Glycemic Balance Without Other Pancreatic Cells

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels.

4 Sep 2024

Study Identifies Genes for Healthier Rice with Low Glycemic Index and High Protein

A team of researchers at the International Rice Research Institute (IRRI) has identified genes and markers responsible for low glycemic index (GI) and high protein content in rice, using genetics and artificial intelligence classification methods.

2 Sep 2024

Evolution of Blood Sugar Regulation in Neotropical Bats

Humans must regulate blood sugar concentrations to stay healthy and to fuel our cells. Too little or too much can cause serious health complications, and high blood sugar is a hallmark of the metabolic condition, diabetes. New research from the Stowers Institute for Medical Research may enable potential solutions to metabolic disease by turning to evolution and to bats.

29 Aug 2024

Bifidobacterium in Maternal Gut Found to Alter Fetal Brain Growth

Bifidobacterium breve supplementation in pregnant mice alters fetal brain metabolism, highlighting its role in enhancing gestational health and development.

29 Aug 2024

New Discovery in Mitochondrial DNA Regulation May Halt Heritable Disease Onset

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

23 Aug 2024

Study Identifies Key Macrophage Subpopulations in MASH Progression and Regression

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.

23 Aug 2024

Mitochondrial DNA Enzymes Prevent Disease Mutations

Researchers at the University of Queensland have identified a mechanism in DNA that controls the inheritance of disease-causing mutations.

22 Aug 2024

Breakthrough Research Reveals Early Development of Eye Macrophages in Mice

Macrophages, also known as scavenger cells, are part of our immune system. They destroy invading pathogens and are found in the organs and the bloodstream.

20 Aug 2024

Harnessing Proteomics to Explore the Role of Probiotic Bacteria in Human Health

The currently available proteomics strategies can be used to identify and quantify probiotic bacterial proteins.

19 Aug 2024

Mechanical Manipulation of Stem Cells Promises New Treatments

New stem cell therapies may result from a novel method that McGill researchers have created for mechanically modifying stem cells, which has not yet reached its full therapeutic potential.

14 Aug 2024

Emerging Treatments and Drug Repositioning for NAFLD and NASH

The current research on drug candidates and molecular targets being clinically tested for the treatment of non-alcoholic steatohepatitis (NASH) and NAFLD.

9 Aug 2024

Research Unlocks Secrets of Stem Cell Retention in Bone Marrow

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells. The findings, made in mice, were published today in the journal Science.

9 Aug 2024

Geographic Origin Plays Key Role in Tuberculosis Infection, Harvard Study Finds

For some forms of tuberculosis, the chances that an exposed person will get infected depend on whether the individual and the bacteria share a hometown, according to a new study comparing how different strains move through mixed populations in cosmopolitan cities.

2 Aug 2024

Researchers Uncover Unique Protective Mechanism in Pancreatic Cells

Researchers from the University of Cologne have revealed a mechanism protecting pancreatic β-cells, which are crucial for insulin production from inflammatory cell death. The study investigated the role of receptor-interacting protein kinase 1 (RIPK1) in regulating β-cell survival.

1 Aug 2024