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Study Reveals How DNA Reorganization Helps Cells Survive UV Damage

Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer.

13 Mar 2025

Study Explores the Physiological Role of Nwd1 Gene in MASH Pathogenesis

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

12 Mar 2025

Microbiome-Based Approach Shows Promise for Treating Ulcerative Colitis

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health.

12 Mar 2025

Protective ‘Slime’ In The Brain May Help Prevent Aging And Neurodegeneration

The study shows that boosting mucin-type O-glycosylation in aged mice reinforces the blood-brain barrier and improves memory, paving the way for new treatments.

10 Mar 2025

New Method Creates Stable Fatty Acid Solutions for Biological Research

FAs are important in cellular processes such as membrane structure, energy storage, and signaling. However, challenges remain in preparing stable FA solutions due to their amphipathic nature and low solubility in water.

6 Mar 2025

Macrophages Use Bacterial Debris To Fine-Tune Immune Responses

Findings reveal macrophages' role in immune modulation through bacterial metabolites, paving the way for improved therapies for infections and inflammation.

6 Mar 2025

Synthetic Microbiome Treatment Prevents C. difficile Infection in Mice

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

4 Mar 2025

Unlocking the Role of lncRNAs in MASLD and Liver Fibrosis

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed non-alcoholic fatty liver disease (NAFLD), represents a widespread health concern, impacting approximately 30% of the global adult population.

3 Mar 2025

Understanding Cell States Could Lead to More Personalized Leukemia Therapies

Myeloid leukaemias are among the most aggressive blood cancers and have low survival rates. Today, leukaemia patients undergo genetic analysis to identify mutations and select the most appropriate treatment.

26 Feb 2025

T Cells May Hold the Secret to Fighting Dengue Virus

Children who experience multiple cases of dengue virus develop an army of dengue-fighting T cells, according to a new study led by scientists at La Jolla Institute for Immunology (LJI).

25 Feb 2025

New Lipid Nanoparticles Deliver mRNA for Lung Tissue Regeneration

New research from the Perelman School of Medicine at the University of Pennsylvania suggests that a combination of messenger RNA (mRNA) and a novel lipid nanoparticle (LNP) could potentially be used to repair lung damage.

24 Feb 2025

Engineered Phages Deliver Therapeutic Proteins to Intestines

Engineered phages transform gut bacteria into drug delivery systems, releasing therapeutic proteins that reduce inflammation and promote satiety in obesity.

19 Feb 2025

New Atlas Maps How Aging Breast Tissue Contributes to Cancer Risk

Aging is a privilege, but it also brings risks-including an increased likelihood of developing age-related diseases including cancer.

14 Feb 2025

Infant Cystic Fibrosis Linked to Stunted Microbiome Development

Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut microbiome (communities of bacteria) of infants with cystic fibrosis (CF) compared to that of healthy infants, and how these alterations may adversely affect their health.

14 Feb 2025

Research Sheds Light on How Obesity Affects Gene Expression in Fat Cells

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC.

11 Feb 2025

Uncovering a New Mechanism in Immune Cell Regulation During Parasitic Infections

Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune response against parasites.

10 Feb 2025

Omega-3 Slows Aging at the DNA Level, Vitamin D and Exercise Boost the Effect

A clinical trial found that omega-3 supplementation modestly slowed biological aging, with additional benefits when combined with vitamin D and exercise.

4 Feb 2025

First Cell Atlas of Focal Cortical Dysplasia Offers New Insights for Treatment

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug-resistant epilepsy.

31 Jan 2025

Temperature-Sensitive Protein Enables Non-Invasive Control of Cellular Behavior

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

30 Jan 2025

Researchers Apply Advanced AI Genetics Models to Study Parkinson's Disease

Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD treatment.

29 Jan 2025