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Unlocking the Secrets of Neural Ion Channels

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions enter a cell-and the molecular gatekeepers that help control them.

30 Oct 2025

Reversible Epigenetic Switches Influence Memory Formation

Our experiences leave traces in the brain, stored in small groups of cells called "engrams". Engrams are thought to hold the information of a memory and are reactivated when we remember, which makes them very interesting to research on memory and age- or trauma-related memory loss.

30 Oct 2025

Researchers Uncover How Pseudomonas Bacteria Sense and Build Biofilms

The bacterium known as Pseudomonas aeruginosa is an unwelcome visitor in the human body. Serious infections can result when a bunch of these bugs settle together on a surface to form a biofilm - a community of microbes like the slime on spoiled food, but in this case residing inside a person.

29 Oct 2025

RNA Modifications Found to Guide Stem Cell Development into Retinal Cells

Cells contain a blueprint in the form of DNA that dictates what they can make.

29 Oct 2025

Female Mosquitoes Use Precise Movements to Decide Successful Mating

A female mosquito only gets one shot to get reproduction right: She mates just a single time in her entire life.

29 Oct 2025

Study Reveals How Blood Vessels Drive Neuron Movement in the Brain

Researchers have discovered how newly created neurons depend on blood flow in the adult brain to travel from their site of origin to their final location.

29 Oct 2025

AI-Guided Protein Engineering Creates Smart Receptors for Cancer Immunotherapy

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment.

29 Oct 2025

AI-Powered Approach Boosts Protein Production Efficiency in E. coli

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, including pharmaceuticals, industrial enzymes, and diagnostic antibodies.

29 Oct 2025

Light-Based Sensor Continuously Detects Vaccine Quality

A group of researchers from Purdue University and Merck & Co. Inc., referred to as Merck Sharp & Dohme Corp. in regions outside the U.S. and Canada, has recently unveiled a novel analytical tool that may assist pharmaceutical companies in enhancing vaccine production through expedited monitoring and analysis.

29 Oct 2025

Retinal Implant Restores Sight for Patients With Macular Degeneration

A wireless photovoltaic implant shows promise in restoring central vision for patients with macular degeneration, enhancing visual acuity and independence.

29 Oct 2025

Researchers Discover Novel Clubroot Resistance Gene Crr5 in Chinese Cabbage

Clubroot disease, caused by Plasmodiophora brassicae, is a devastating soil-borne pathogen that severely threatens global production of cruciferous crops.

28 Oct 2025

Discovery of Hidden Antibiotic Offers Hope in the Fight Against Superbugs

Chemists from the University of Warwick and Monash University have discovered a promising new antibiotic that shows activity against drug-resistant bacterial pathogens, including MRSA and VRE.

28 Oct 2025

Aptamer Technology Offers Breakthrough in Identifying Zombie Cells

When it comes to treating disease, one promising avenue is addressing the presence of senescent cells.

28 Oct 2025

Electromagnetic Levitation Enables Noninvasive Sorting of Cancer and Healthy Cells

Stanford Medicine researchers invent an electromagnetic device that can gently sort different types of cells by levitating them to different heights.

28 Oct 2025

Mutation in NAMPT Gene Found to Cause Rare Neurological Disease

An international research team, led by Shinghua Ding at the University of Missouri, has identified a previously unknown genetic disease that affects movement and muscle control.

28 Oct 2025

Discovery of Glucocorticoid Receptor Multimerization Opens Path to Safer Therapies

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

28 Oct 2025

TRF1 Knockout Mice Exhibit Healthier Metabolic States Without Telomere Shortening

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

28 Oct 2025

Rhizosphere Metabolites Play Key Role in Regulating the Distribution of Antibiotic Resistance Genes

Their study reveals that rhizosphere metabolites-substances secreted by plant roots-play a crucial role in regulating the distribution of manure-derived ARGs in both the soil and plant tissues.

27 Oct 2025

Enhancing Ovarian Cancer Treatment with Multi-Modal Immunotherapy Approach

Results of a study led by researchers at Roswell Park Comprehensive Cancer Center show that combining two types of immunotherapy - engineered T cells that secrete bispecific T cell engagers (BiTEs) and an immune checkpoint inhibitor - can alter the tumor microenvironment to launch a stronger attack against ovarian cancer and reduce the risk of relapse.

27 Oct 2025