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Molecular Blueprint Reveals Structure and Delivery of Botulinum Toxin

Researchers at Stockholm University have succeeded in creating a molecular blueprint of how one of the world's most dangerous toxins, botulinum toxin, is structured, stabilized, delivered and released.

28 Aug 2025

Aptamer Group Introduces Novel Biomarker Discovery Service

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, today announced the launch of its biomarker discovery service, offering researchers in pharmaceutical, biotechnology, and diagnostic development an innovative approach to identify and validate new disease markers.

28 Aug 2025

PV Interneurons Regulate Social Behavior and Empathy in Mice

A special set of neurons directs mice's attention to or away from their peers, depending on the situation. The Kobe University discovery has implications for finding causes for neuropsychiatric conditions such as autism spectrum disorder or schizophrenia.

27 Aug 2025

Belgian Scientists Reveal How Dendritic Cells Respond to Lipid Nanoparticles

Belgian scientists have uncovered new details about how the immune system responds to vaccines. Dendritic cells, which are key immune messengers that help kick-start the body's defenses, show specific responses to lipid nanoparticles.

27 Aug 2025

Bacteria Pass Down Environmental Memories Across Generations

Bacteria aren't just mindless microbes. New research from the Hebrew University of Jerusalem reveals that single bacterial cells can carry a "memory" of their past environments-passing it down through generations-before eventually forgetting.

27 Aug 2025

New "DNA Organizer" Found to Be Essential for Sperm Stem Cell Development

A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermaotogonial stem cells (SSCs), the stem cells that give rise to sperm.

27 Aug 2025

New Computational Tool Enhances Cancer Tissue Analysis for Personalized Treatment

Scientists at the Icahn School of Medicine at Mount Sinai have developed a powerful new computational tool that could transform how cancer tissues are analyzed and help pave the way for more personalized treatments.

27 Aug 2025

Genes and Diet Work Together to Regulate the Liver’s Circadian Clock

Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism.

27 Aug 2025

RNA Binding Proteins and EVs Offer Clues to Cancer's Evasion of Immune Response

Certain types of biochemical processes can impair the immune system's ability to recognize and kill cancer cells. Purdue University's W. Andy Tao and his associates have developed a new way to study these processes.

27 Aug 2025

How Bacillus Spores Initiate Self-Healing Concrete

Findings on Bacillus pasteurii spore germination and impermeability mechanisms offer insights into developing effective microbial self-healing concrete systems.

27 Aug 2025

New Research Explains How Alcohol Inhibits Gut Health

Alcohol-associated liver disease (ALD) is a leading cause of liver transplantation and mortality globally, and its effect is only increasing.

27 Aug 2025

New Imaging Method Reveals Lipid Distribution in Tiny Worms with High Precision

Understanding how fat molecules are distributed and function in living organisms is key to uncovering mechanisms of aging, disease, and metabolism.

25 Aug 2025

Researchers Decode How Plants Distribute Essential Amino Acids

Plants produce all amino acids essential for human life. This commonly occurs in specialised cell organelles, so-called plastids.

25 Aug 2025

Scientists Use Single-Cell Proteomics to Track Blood Cell Differentiation

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through the course of health or disease.

25 Aug 2025

Cryo-Optical Microscopy Captures Instantaneous Snapshots of Cellular Waves

Optical microscopy is a key technique for understanding dynamic biological processes in cells, but observing these high-speed cellular dynamics accurately, at high spatial resolution, has long been a formidable task.

25 Aug 2025

Organ Development Shaped Equally by Mechanics and Biochemistry

A new study looks at the physical forces that help shape developing organs. Scientists in the past believed that the fast-acting biochemistry of genes and proteins is responsible for directing this choreography.

22 Aug 2025

Genome-Wide Screening Approach Uncovers Genetic Brakes on Blood Cancer Growth

Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers.

22 Aug 2025

Machine Learning Framework Reveals Rules of Cellular Self Organization

One of the most fundamental processes in all of biology is the spontaneous organization of cells into clusters that divide and eventually turn into shapes – be they organs, wings or limbs.

22 Aug 2025

Genetic Signatures of Neural Progenitor Cells Uncovered in the Adult Brain

For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis – the birth of new neurons – is now a widely accepted phenomenon in the adult brain, offering promising avenues for treating many neurological conditions.

22 Aug 2025

Ancient Interbreeding Provided Modern Humans with Useful Genetic Variation

A new study provides fresh evidence that ancient interbreeding with archaic human species may have provided modern humans with genetic variation that helped them adapt to new environments as they dispersed across the globe.

22 Aug 2025