Genome News and Research

RSS

New Genome Editing Technology Achieves Precise Targeted Insertion of DNA Segments

A new genome editing technology was developed by GAO Caixia’s group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS). This technology achieves successful and accurate targeted insertion of large DNA segments in plants.

26 Apr 2023

A Study on Genetic Markers and Their Efficiency in the Cultivation of High-Quality Rice

For individual organisms, genetic markers, like simple sequence repeat (SSR), fragment length polymorphisms (RFLP), and single-nucleotide polymorphisms (SNPs), offer unique identifiers. This helps in the determination of important genetic variations in plants, enabling modern plant breeding to choose high-quality crop varieties.

26 Apr 2023

Interpretable Machine Learning Framework Helps Optimize Chromosome Design and Synthesis

Artificially synthesizing genomes has numerous applications, including medical research and industrial strains. Scientists are continuously progressing in the depth and breadth of genome design and synthesis, from Craig Venter’s team’s synthesis of the artificial life JCVI-syn1.0 in 2010 to the rewriting and synthesis of the prokaryotic E. coli genome, and the Sc2.0 project’s artificial synthesis of the yeast genome.

26 Apr 2023

Metabolic Network Compatibility Not Likely the Limiting Factor in Prokaryotic Endosymbiosis

"One of the great mysteries of biology," says Eric Libby, former SFI Postdoctoral Fellow, now an associate professor at the Integrated Science Lab (IceLab), Umeå University in Sweden, "is eukaryogenesis, or how eukaryotes arose." Scientists consider this to be a period of major evolutionary transition, critical to our understanding of the history and evolution of life on Earth.

25 Apr 2023

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease.

24 Apr 2023

Spatial Organization of Chromosomes and the Role of DNA Tension

Two protein complexes are primarily responsible for chromosomal spatial organization in human cell nuclei. DNA tension has an unanticipated function in this. Together with Austrian colleagues, nanoscientist Cees Dekker and his PhD candidate Roman Barth of TU Delft’s Kavli Institute of Nanoscience published their detailed visualization in Nature on April 19th, 2023.

21 Apr 2023

Gene-Silencing Complexes Work Together to Render X Chromosomes Inactive

Two protein complexes are involved in the mysterious process of shutting off one X chromosome in female mammals, according to a new study from RIKEN. This result could aid in the understanding of how specific tumors in women develop.

21 Apr 2023

A Previously Unknown Mechanism for DNA Folding Revealed

A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics.

20 Apr 2023

The Function of ANKLE1 in the Prevention of DNA Damage and Autoimmunity

The University of Hong Kong (HKU) School of Biological Sciences research team led by Dr. Gary Ying Wai Chan has uncovered the function of a unique enzyme called ANKLE1.

19 Apr 2023

Genomics Surveillance of Wheat Blast Fungus may be an Effective Disease Management Tool

Pests and diseases may reduce global wheat yields by over 20%. A study published April 11th in the open access journal PLOS Biology by Sergio Latorre at University College London, UK and colleagues suggest that genomic surveillance may be an effective disease management tool with the ability to trace lineages of emerging crop diseases, and to identify genetic traits for breeding disease-resistant lines.

18 Apr 2023

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

At St Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard, researchers have shown how prime editing could help correct the mutation that results in sickle cell disease in a possibly curative method.

18 Apr 2023

New Method Uses Light to Activate Protein Functions

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail.

18 Apr 2023

Leveraging Advanced Genomic Approaches for Amphibian Conservation

Morris Animal Foundation and Revive & Restore recently announced the funding of five new projects building genomic tools for amphibian conservation.

18 Apr 2023

Genetic Changes Affecting Cartilage Cell Maturation may Influence Adult Height, Study Shows

When it comes to height, our fate is sealed along with our growth plates—cartilage near the ends of bones that hardens as a child develops.

17 Apr 2023

Researchers Show How a Virus can Induce Cleavage of Human Chromosome 11 to Cause Cancer

The Epstein-Barr virus (EBV) is easily spread through bodily fluids, primarily saliva, such as kissing, shared drinks or using the same eating utensils.

17 Apr 2023

New Clinical RNA Sequencing Platform Helps Facilitate Research into Rare Genetic Conditions

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

17 Apr 2023

Researchers Generate Largest Atlas of Post-Zygotic Genome Mutations in Human Tissue Researchers Have ...

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled -; a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

17 Apr 2023

Next-Generation Sequencing Provides New Insights into Mutations of Mitochondrial DNA

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

17 Apr 2023

New Mechanism Controlling Cellular Proliferation in Response to Serum Revealed

Researchers of the Genome Dynamics Project team at Tokyo Metropolitan Institute of Medical Science revealed new mechanism controlling cellular proliferation in response to serum, which triggers growth of resting cells.

13 Apr 2023

Comprehensive Sequencing of the Little Skate Genome

Rutgers geneticists, working with an international team of scientists, have conducted the most comprehensive sequencing yet of the complete DNA sequence of the little skate – which, like its better-known cousin, the stingray, has long been viewed as enigmatic because of its shape.

13 Apr 2023

Genome News and Research

New Genome Editing Technology Achieves Precise Targeted Insertion of DNA Segments

A Study on Genetic Markers and Their Efficiency in the Cultivation of High-Quality Rice

Interpretable Machine Learning Framework Helps Optimize Chromosome Design and Synthesis

Metabolic Network Compatibility Not Likely the Limiting Factor in Prokaryotic Endosymbiosis

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Spatial Organization of Chromosomes and the Role of DNA Tension

Gene-Silencing Complexes Work Together to Render X Chromosomes Inactive

A Previously Unknown Mechanism for DNA Folding Revealed

The Function of ANKLE1 in the Prevention of DNA Damage and Autoimmunity

Genomics Surveillance of Wheat Blast Fungus may be an Effective Disease Management Tool

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

New Method Uses Light to Activate Protein Functions

Leveraging Advanced Genomic Approaches for Amphibian Conservation

Genetic Changes Affecting Cartilage Cell Maturation may Influence Adult Height, Study Shows

Researchers Show How a Virus can Induce Cleavage of Human Chromosome 11 to Cause Cancer

New Clinical RNA Sequencing Platform Helps Facilitate Research into Rare Genetic Conditions

Researchers Generate Largest Atlas of Post-Zygotic Genome Mutations in Human Tissue Researchers Have ...

Next-Generation Sequencing Provides New Insights into Mutations of Mitochondrial DNA

New Mechanism Controlling Cellular Proliferation in Response to Serum Revealed

Comprehensive Sequencing of the Little Skate Genome

Genetics & Genomics - Second Edition eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics