Genome News and Research

RSS

Study Uncovers Somatic Mutations That Play a Role in Common Form of Adult Epilepsy

Epilepsy affects approximately 1-in-26 people and the most common form, known as temporal lobe epilepsy (TLE), often cannot be adequately treated with anti-seizure medications.

2 May 2023

Genome Sequencing of 'Lablab Bean' Paves Way for Wider Cultivation of the African Crop

An international team of researchers has fully sequenced the genome of a climate-resilient bean that could bolster food security in drought-prone regions.

2 May 2023

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Recent research from Temple University’s Lewis Katz School of Medicine and the University of Nebraska Medical Center demonstrates that gene-editing therapy aimed at two targets - HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that aids the virus getting into cells—can effectively eliminate HIV infection.

2 May 2023

Markers Indicating Early Signs of Schizophrenia Identified

For the first time, a global study group headed by investigators at Virginia Commonwealth University has found markers that might point out early if a person is susceptible to schizophrenia in the early stage itself.

28 Apr 2023

Deletion of Human Genome Information Helped in Differentiation Between Humans and Other Mammals

As per new research headed by scientists at Yale and the Broad Institute of MIT and Harvard, what the human genome is missing when compared to the genomes of other primates may be as significant to the development of humankind as what has been added at the time of human evolutionary history.

28 Apr 2023

The Origins of Human Accelerated Regions

Large parts of the human genome were changed over a million years ago due to a random event during egg or sperm formation that resulted in the deletion, duplication, or reversal of sections of DNA. Investigators have demonstrated that those structural variants likely set off a cascade of other fast alterations in human DNA that may underpin unique human traits, particularly the brain.

28 Apr 2023

3D Genome Mapping may Lead to Targeted Therapeutic Options for Ependymoma

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

28 Apr 2023

Understanding the Origins of Human Disease Using the Power of Evolutionary Genomics

Hundreds of scientific studies have been conducted over the years to find the genes underlying common human traits, from eye color to intelligence and physical and mental illnesses.

28 Apr 2023

Research Shows How Mammalian Genomes Have Developed Over the Course of Evolution

Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease?

28 Apr 2023

Highly Tissue-Specific lincRNA Markers Could Indicate the Presence of Disease

Our genetic code includes over 15,000 specific sections that can be made into molecules called lincRNAs.

27 Apr 2023

Capturing Viruses in a Lipid Trap

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

26 Apr 2023

Membrane-Remodeling Proteins in Cyanobacteria are Similar to Protein Found in Higher Organisms

The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks.

26 Apr 2023

New Genome Editing Technology Achieves Precise Targeted Insertion of DNA Segments

A new genome editing technology was developed by GAO Caixia’s group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS). This technology achieves successful and accurate targeted insertion of large DNA segments in plants.

26 Apr 2023

A Study on Genetic Markers and Their Efficiency in the Cultivation of High-Quality Rice

For individual organisms, genetic markers, like simple sequence repeat (SSR), fragment length polymorphisms (RFLP), and single-nucleotide polymorphisms (SNPs), offer unique identifiers. This helps in the determination of important genetic variations in plants, enabling modern plant breeding to choose high-quality crop varieties.

26 Apr 2023

Interpretable Machine Learning Framework Helps Optimize Chromosome Design and Synthesis

Artificially synthesizing genomes has numerous applications, including medical research and industrial strains. Scientists are continuously progressing in the depth and breadth of genome design and synthesis, from Craig Venter’s team’s synthesis of the artificial life JCVI-syn1.0 in 2010 to the rewriting and synthesis of the prokaryotic E. coli genome, and the Sc2.0 project’s artificial synthesis of the yeast genome.

26 Apr 2023

Metabolic Network Compatibility Not Likely the Limiting Factor in Prokaryotic Endosymbiosis

"One of the great mysteries of biology," says Eric Libby, former SFI Postdoctoral Fellow, now an associate professor at the Integrated Science Lab (IceLab), Umeå University in Sweden, "is eukaryogenesis, or how eukaryotes arose." Scientists consider this to be a period of major evolutionary transition, critical to our understanding of the history and evolution of life on Earth.

25 Apr 2023

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease.

24 Apr 2023

Spatial Organization of Chromosomes and the Role of DNA Tension

Two protein complexes are primarily responsible for chromosomal spatial organization in human cell nuclei. DNA tension has an unanticipated function in this. Together with Austrian colleagues, nanoscientist Cees Dekker and his PhD candidate Roman Barth of TU Delft’s Kavli Institute of Nanoscience published their detailed visualization in Nature on April 19th, 2023.

21 Apr 2023

Gene-Silencing Complexes Work Together to Render X Chromosomes Inactive

Two protein complexes are involved in the mysterious process of shutting off one X chromosome in female mammals, according to a new study from RIKEN. This result could aid in the understanding of how specific tumors in women develop.

21 Apr 2023

A Previously Unknown Mechanism for DNA Folding Revealed

A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics.

20 Apr 2023

Genome News and Research

Study Uncovers Somatic Mutations That Play a Role in Common Form of Adult Epilepsy

Genome Sequencing of 'Lablab Bean' Paves Way for Wider Cultivation of the African Crop

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Markers Indicating Early Signs of Schizophrenia Identified

Deletion of Human Genome Information Helped in Differentiation Between Humans and Other Mammals

The Origins of Human Accelerated Regions

3D Genome Mapping may Lead to Targeted Therapeutic Options for Ependymoma

Understanding the Origins of Human Disease Using the Power of Evolutionary Genomics

Research Shows How Mammalian Genomes Have Developed Over the Course of Evolution

Highly Tissue-Specific lincRNA Markers Could Indicate the Presence of Disease

Capturing Viruses in a Lipid Trap

Membrane-Remodeling Proteins in Cyanobacteria are Similar to Protein Found in Higher Organisms

New Genome Editing Technology Achieves Precise Targeted Insertion of DNA Segments

A Study on Genetic Markers and Their Efficiency in the Cultivation of High-Quality Rice

Interpretable Machine Learning Framework Helps Optimize Chromosome Design and Synthesis

Metabolic Network Compatibility Not Likely the Limiting Factor in Prokaryotic Endosymbiosis

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Spatial Organization of Chromosomes and the Role of DNA Tension

Gene-Silencing Complexes Work Together to Render X Chromosomes Inactive

A Previously Unknown Mechanism for DNA Folding Revealed

Genetics & Genomics - Second Edition eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics