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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Unraveling the Molecular Landscape of Parietal Cell Development

Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the normal activity of parietal cells (PCs) in the stomach, the only cells in the body that produce acid.

13 May 2024

Engineering Blood Vessels to Image Bioluminescence Deep Within the Brain

Researchers frequently tag cells with fluorescent proteins, which enable them to monitor tumor growth or quantify alterations in gene expression that transpire during cell differentiation.

13 May 2024

Colossal Biosciences and University of Melbourne Partner to Save Northern Quolls from Invasive Cane Toads

Today scientists from Colossal Biosciences, the world’s first de-extinction company, and the University of Melbourne announce a major step forward in the effort to save Australia’s endangered northern quoll (Dasyurus hallucatus) from the invasive cane toad.

11 May 2024

Unraveling the Rhizobia-Diatom Relationship in the Ocean

Nitrogen is an essential component of all living organisms. It is also the key element controlling the growth of crops on land, as well as the microscopic oceanic plants that produce half the oxygen on our planet.

10 May 2024

Understanding Genome Scrambling in Oikopleura Dioica

When two animals look the same, eat the same, behave the same way, and live in similar environments, one might expect that they belong to the same species.

10 May 2024

Decoding Aging: The Role of Stochastic Variation in Biological Clocks

Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth.

10 May 2024

New Tool Precisely Edits Epigenetic Modifications

Powerful epigenetic editing technology was developed as a result of research by the Hackett group at EMBL Rome. This technology allows for the precise programming of chromatin modifications.

10 May 2024

Researchers Uncover New Genetic Mutation Linked to Rare Form of Congenital Thyroid Abnormality

A team of researchers from the University of Chicago, in collaboration with the Free University of Brussels and the University of Washington, have uncovered a genetic mutation in a non-coding region of DNA that alters the regulation of the thyroid, leading to a rare form of congenital thyroid abnormality.

9 May 2024

New Study Uncovers Direct Link Between Learning and Memory Impairment and Specific Gene

A gene previously associated with intellectual disability has been discovered to play a role in regulating learning and memory in mice.

9 May 2024

Rice University Develops AI-Powered Tools for Unraveling Microbial Genomes

Since the first microbial genome was sequenced in 1995, scientists have reconstructed the genomic makeup of hundreds of thousands of microorganisms and have even devised methods to take a census of bacterial communities on the skin, in the gut, or in soil, water and elsewhere based on bulk samples, leading to the emergence of a relatively new field of study known as metagenomics.

8 May 2024

mRNA Dynamics Guide Cell Identity Formation

New research from Hebrew University sheds light on the regulation of mRNA during the development of the embryo. The research separates newly-transcribed from pre-existing mRNA in zebrafish embryos using a combination of single-cell RNA-Seq and metabolic labeling.

8 May 2024

Unlocking Glucose-Driven Mechanisms of Immunosuppression in Glioblastoma

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

6 May 2024

Targeting RNA Modifications: A Novel Approach for Neuroblastoma Treatment

Neuroblastoma is a common pediatric cancer that originates in developing nerve cells outside the brain.

6 May 2024

New Insights into E. coli's UTI Survival Strategy

Due to anatomical peculiarities, women are particularly vulnerable to UTIs; nearly 50% of them will experience one at some point in their lives.

6 May 2024

Study Demonstrates How the Warburg Effect is Crucially Linked to Cancer Progression

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming.

3 May 2024

Epigenomic Analysis Reveals Potential Treatment Avenues for ALS

For most patients, it's unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death.

3 May 2024

Understanding How Genetic Drivers Influence the Evolution of Photosynthesis Mechanism in Tillandsia

Researchers at the University of Vienna, along with collaborators from France, Germany, Switzerland and the USA, have achieved a major breakthrough in understanding how genetic drivers influence the evolution of a specific photosynthesis mechanism in Tillandsia (air plants).

2 May 2024