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Macrophages Use Bacterial Debris To Fine-Tune Immune Responses

Findings reveal macrophages' role in immune modulation through bacterial metabolites, paving the way for improved therapies for infections and inflammation.

6 Mar 2025

Discovery of Ball-and-Chain Mechanism Sheds Light on Ion Channel Regulation

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a "ball-and-chain" channel-plugging mechanism, according to investigators at Weill Cornell Medicine.

5 Mar 2025

Arab Pangenome Reference Provides New Path for Advancing Precision Medicine

Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision medicine, a publication in Nature Medicine reveals.

5 Mar 2025

Colossal Creates the Colossal Woolly Mouse, Showcasing Breakthroughs in Multiplex Genome Editing and Trait Engineering on the Path to a Mammoth

In an extraordinary achievement of advanced multiplexed genome engineering, Colossal Biosciences announces the birth of the Colossal Woolly Mouse—mice engineered to express multiple key mammoth-like traits that provide adaptations to life in cold climates.

5 Mar 2025

New Insights Into Ageing Revealed

The way in which blood stem cells evolve over a lifespan differs greatly between humans and mice, new research reveals. The findings provide a new understanding of the critical factors that influence tissue ageing.

5 Mar 2025

New CRISPR Method Enhances Surveillance of Antibiotic Resistance in Wastewater

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals.

4 Mar 2025

New Genetic Clues Could Explain Prostate Cancer’s Aggressive Progression

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.

4 Mar 2025

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code.

4 Mar 2025

Study Clarifies Genetic Thresholds for Diagnosing SCA6

The Department of Neurology at Niigata University and National Center of Neurology and Psychiatry has identified pathogenic thresholds for the CAG repeat units (RU) of the CACNA1A gene that causes SCA6.

3 Mar 2025

Quantifying 3D Cell Shape During Early Development

For the last three decades, biologists and computer scientists have dedicated significant effort to quantifying the 3D shape of cells and analyzing their interactions.

3 Mar 2025

Unraveling PDMA's Influence on Rhizosphere Microbial Communities

The rhizosphere is influenced by a range of exudates released by plant roots. These root exudates serve as an “intermediary” between the plant and the soil, modifying the root's immediate environment.

3 Mar 2025

Study Reveals Complex Neural Modules Behind Motor Control

For nearly a century, scientists have known that different parts of the human brain's cortex control different body movements.

28 Feb 2025

Novel Genetic Mechanism Controlled by Leaf Microbiota

A recent investigation has uncovered a genetic network within plants that regulates the growth of individual leaves and enables adaptation to environmental conditions. This discovery holds the potential for creating crops with enhanced drought tolerance.

28 Feb 2025

Rare Gene Variants Increase Type 2 Diabetes Prevalence in Asian Indian Families

A new study published in Communications Medicine, a Nature publication, details the discovery of rare gene variants that increase the prevalence of Type 2 diabetes in multiple generations of Asian Indian people.

27 Feb 2025

Study Unveils Phage-Bacteria Dynamics in the Early Life Gut Microbiome

A world of microbes resides within the gut of every human being. This vast microbial community, the microbiome, which includes bacteria and viruses, has repeatedly demonstrated its ability to actively contribute to both health and disease.

26 Feb 2025

Understanding Cell States Could Lead to More Personalized Leukemia Therapies

Myeloid leukaemias are among the most aggressive blood cancers and have low survival rates. Today, leukaemia patients undergo genetic analysis to identify mutations and select the most appropriate treatment.

26 Feb 2025

RNA Splicing Errors May Hold the Key to Beating Gliomas Using Immunotherapy

Identifying splicing-related neoantigens in gliomas opens new avenues for immunotherapy, enhancing treatment strategies for this challenging brain tumor.

26 Feb 2025

Wayne State Researchers Receive $1.8 Million Grant for Mitophagy Study

A recent award from the National Institute of General Medical Sciences of the National Institutes of Health will aid Wayne State University researchers in their exploration of the underlying biology of several diseases.

22 Feb 2025

Targeting NMDA Receptor Subunit Shows Promise for Fragile X Syndrome

Building on more than two decades of research, a study by MIT neuroscientists at The Picower Institute for Learning and Memory reports a new way to treat pathology and symptoms of fragile X syndrome, the most common genetically-caused autism spectrum disorder.

21 Feb 2025

Researchers Unveil Process Behind Cellular Recycling and Waste Removal

A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling process and create ‘garbage bags’ to remove proteins.

21 Feb 2025