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Cutting-edge genomic tools used to investigate health effects of Chernobyl radiation exposure

In two landmark studies, researchers have used cutting-edge genomic tools to investigate the potential health effects of exposure to ionizing radiation, a known carcinogen, from the 1986 accident at the Chernobyl nuclear power plant in northern Ukraine.

From National Cancer Institute (NCI) 23 Apr 2021

National DNA Day 2021: An Interview with Professor George Church

In celebration of National DNA Day, AZoLifeSciences interviews renowned DNA expert Professor George Church about his life-long career in DNA research.

From Harvard Medical School 23 Apr 2021

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Researchers have now identified how SARS viruses improve the production of viral proteins in infected cells such that new copies of the virus can be produced.

23 Apr 2021

Study finds raised levels of specific immune cells in asymptomatic people with COVID-19

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Researchers uncover a key genetic culprit in the development of acute lymphoblastic leukemia

Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).

21 Apr 2021

Supercomputer simulations reveal the behavior of dominant G form SARS-CoV-2 strain

Large-scale supercomputer simulations at the atomic level show that the dominant G form variant of the COVID-19-causing virus is more infectious partly because of its greater ability to readily bind to its target host receptor in the body, compared to other variants.

19 Apr 2021

New CRISPR technology allows scientists to switch off any gene in human cells

Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.

19 Apr 2021

“Expansion Hunter” approach can detect DNA errors

Researchers from Radboud University Medical Center have successfully detected hidden genetic defects by using an existing technique on existing datasets. The team demonstrated that the “Expansion Hunter” approach can detect DNA errors that cause repeat expansion diseases, like ataxia—a movement disorder.

16 Apr 2021

Researchers use information embedded in microbial genes as a biosensor of ocean health, productivity

Scientists from the University of California, Irvine, analyzed gains and losses in the genes of phytoplankton samples gathered from all major ocean regions to develop the most refined and highest-resolution map that shows where these photosynthetic organisms either survive or are forced to adapt to restricted amounts of main nutrients, nitrogen, iron, and phosphorus.

16 Apr 2021

Study reveals RNA regulatory mechanisms within transcription-translation couplings

To gain a better understanding of how bacterial RNA gives rise to proteins scientists are now focusing on the special way this process takes place in bacteria.

15 Apr 2021

Ebola virus protein changes shape by using human RNA

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape--and biologists are taught that defined shape dictates the protein's destined function. Tens of thousands of singular shapes drive the tens of thousands of needed functions.

15 Apr 2021

Scientists characterize the genetic diversity of populations in the South Pacific

Describing the genetic diversity of human populations is essential to improve our understanding of human diseases and their geographical distribution.

From Institut Pasteur 15 Apr 2021

Study reveals DNA supercoiling is involved in regulating gene expression

The (when stretched) two-meter-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information.

15 Apr 2021

New method helps map the epigenetics of mouse brain

Histones are essentially small proteins that attach to DNA and store information that can be used to switch individual genes on or off.

14 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

New simpler, faster system for analyzing mutations in SARS-CoV-2

Although it is known that mutations in the SARS-CoV-2 genome occurred and spread, the effect of those mutations is not yet clear.

From Osaka University 14 Apr 2021

CSHL investigator aims to predict the effects of mutations on different tomato varieties

Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of genetic variations--mutations--that affect how genes act and function. Added together, millions of small genetic variations make it hard to predict how a particular mutation will impact any individual.

13 Apr 2021

Genome News and Research

Cutting-edge genomic tools used to investigate health effects of Chernobyl radiation exposure

National DNA Day 2021: An Interview with Professor George Church

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Study finds raised levels of specific immune cells in asymptomatic people with COVID-19

Researchers uncover a key genetic culprit in the development of acute lymphoblastic leukemia

Supercomputer simulations reveal the behavior of dominant G form SARS-CoV-2 strain

New CRISPR technology allows scientists to switch off any gene in human cells

“Expansion Hunter” approach can detect DNA errors

Researchers use information embedded in microbial genes as a biosensor of ocean health, productivity

Study reveals RNA regulatory mechanisms within transcription-translation couplings

Ebola virus protein changes shape by using human RNA

Scientists characterize the genetic diversity of populations in the South Pacific

Study reveals DNA supercoiling is involved in regulating gene expression

New method helps map the epigenetics of mouse brain

Novel test detects HIV reservoir in patients more accurately

New simpler, faster system for analyzing mutations in SARS-CoV-2

CSHL investigator aims to predict the effects of mutations on different tomato varieties

Study reveals genetic risk factors for childhood obsessive-compulsive disorder

Obesity reduces mitochondrial gene expression in fat tissues

Mitochondrial DNA mutations reduce death risk in patients with bowel cancer

Genetics & Genomics - Second Edition eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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