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Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

From University of Pittsburgh 20 Apr 2022

Deeper understanding of genomics support researchers discover new perceptions

In genomic studies, researchers look at a population’s DNA to figure out how genetics affects health and disease.

20 Apr 2022

Study highlights quality control pipeline method to analyze single-cell variation

When it comes to assessing the effects of endocrine-disrupting chemicals (EDCs) or toxins on cancers and other diseases, which target a variety of mechanisms, including the estrogen receptor (ER), one size does not always fit all.

20 Apr 2022

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

According to the Alzheimer’s Association, around 11% of the population, comprising 65-year old and above—in the United States has been diagnosed with Alzheimer’s disease (AD), the most prevalent form of dementia that causes memory loss and cognitive impairment.

19 Apr 2022

New research shows significant variations in B-cells in women with PPD

Jerry Guintivano, PhD, of the University of North Carolina School of Medicine, led an exclusive transcriptome-wide association research that showed substantial changes in B-cells in women with postpartum depression, with pathway observations indicating modified B-cell activation and insulin resistance.

19 Apr 2022

16 distinct cell populations identified in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

AMN1: New gene target for antifungal therapy against cluster-forming pathogenic fungus

A recent study indicates that regulating and deleting a particular gene (AMN1) in yeast might lay the groundwork for a novel method of addressing drug resistance in microbial infections and cancer.

18 Apr 2022

Discovery could help break the cycle of rapid transmission of TB

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

18 Apr 2022

Researchers introduce injectable stem cell assembly, likely to serve as the treatment for cartilage regeneration

Professor Qiuyu Zhang (Northwestern Polytechnical University), Professor Ki-Bum Lee (Rutgers University), and Professor Liang Kong (School of Stomatology, The Fourth Military Medical University) directed this research.

18 Apr 2022

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

A team of researchers at Sweden’s Karolinska Institutet studied how specific immune cells known as innate lymphoid cells (ILCs), which play a role in inflammatory bowel disease (IBD), evolve into mature cells.

18 Apr 2022

Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

From Harvard Medical School 15 Apr 2022

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

According to Weill Cornell Medicine researchers, inhibiting a critical signaling route in brain-resident immune cells may reduce brain inflammation and hence halt the progression of the disease in Alzheimer’s and other neurodegenerative disorders.

15 Apr 2022

A new Yale study identifies a deeper understanding of cancer-relevant genes

According to a Yale Cancer Center study, there is cancer-relevant value in a substantially greater portion of human genes than existing cancer research models suggest, based on a study of over 12,000 human genes.

15 Apr 2022

Scientists discover a special cell in salivary glands that is likely crucial for oral health

Scientists at Scripps Research and the National Institute of Dental and Craniofacial Research have discovered a special type of cell that resides in salivary glands and is likely crucial for oral health.

13 Apr 2022

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

VectorBuilder Inc. has announced the construction of a new R&D and manufacturing center in Guangzhou, China.

From VectorBuilder 12 Apr 2022

Gut viruses contribute to human health, but provoke inflammation when perturbed

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

11 Apr 2022

Study shows how T cell-derived interleukin-22 promotes antibacterial defense of colonic crypts

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea.

11 Apr 2022

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

11 Apr 2022

Scientists gain fascinating insights into the dynamic ultrastructure of the heart

What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating – almost at a molecular level.

11 Apr 2022

Researchers create RNA molecules to address human pancreatic beta cells

Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.

11 Apr 2022

Medicine News and Research

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

Deeper understanding of genomics support researchers discover new perceptions

Study highlights quality control pipeline method to analyze single-cell variation

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

New research shows significant variations in B-cells in women with PPD

16 distinct cell populations identified in a key brain region for substance use disorders

AMN1: New gene target for antifungal therapy against cluster-forming pathogenic fungus

Discovery could help break the cycle of rapid transmission of TB

Researchers introduce injectable stem cell assembly, likely to serve as the treatment for cartilage regeneration

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

Spatial maps offer insights into the battle between melanoma cells and immune cells

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

A new Yale study identifies a deeper understanding of cancer-relevant genes

Scientists discover a special cell in salivary glands that is likely crucial for oral health

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

Gut viruses contribute to human health, but provoke inflammation when perturbed

Study shows how T cell-derived interleukin-22 promotes antibacterial defense of colonic crypts

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

Scientists gain fascinating insights into the dynamic ultrastructure of the heart

Researchers create RNA molecules to address human pancreatic beta cells

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