Biochemistry News and Research

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Rapid Enzyme Screening Unlocks Efficient Routes to Complex Pharmaceuticals

A team of biochemists at the University of California, Santa Cruz, has developed a faster way to identify molecules in the lab that could lead to more effective pharmaceuticals.

6 Feb 2026

New Insights into TRiC and Prefoldin Mechanics

Proteins are the molecular machines of cells. They are manufactured in protein factories known as ribosomes using their blueprint, or genetic information.

6 Feb 2026

Study Reveals Dual Action Protein Protecting Bacteria From Phages

University of Toronto researchers have expanded our understanding of bacterial immunity with the discovery of a new protein that can both sense and counteract viral infections.

5 Feb 2026

Chemistry Breakthrough Improves Gene Delivery, Reduces Side Effects

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

5 Feb 2026

ER-Phagy: A Novel Target for Age-Related Diseases

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health.

4 Feb 2026

Sugar Molecules Point to a New Weapon Against Drug-Resistant Bacteria

Australian researchers have developed a powerful new way to target deadly, drug-resistant bacteria by designing antibodies that recognize a sugar found only on bacterial cells – an advance that could underpin a new generation of immunotherapies for multidrug resistant hospital-acquired infections.

4 Feb 2026

Unusual DNA Structure i-DNA Linked to Cancer Regulation

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes.

3 Feb 2026

New Research Reveals RFC's Dynamic Partnership in DNA Synthesis

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its code and build new strands.

2 Feb 2026

How DNA Leakage into the Cytoplasm Drives Ruijs-Aalfs Syndrome

Although DNA is tightly packed and safeguarded within the cell nucleus, it remains continually at risk of damage from normal metabolic activity and external stressors such as radiation and chemical agents.

2 Feb 2026

Cryo-EM Uncovers Alarmone-Driven RNA Transcription Initiation

Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from deoxyribonucleic acid (DNA) into ribonucleic acid (RNA) can be initiated.

31 Jan 2026

Cellular Garbage Collector Shields Neurons From Alzheimer’s Damage

Researchers at UC San Francisco have identified a hazardous waste collector in the brain that disposes of the toxic clumps of tau protein that can lead to dementia.

29 Jan 2026

Natural Molecular Brake Prevents Uncontrolled DNA Replication in Cells

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we would die.

29 Jan 2026

Using a Powerful Technology to Track Body's Most Elusive Proteins

What can a single molecule in just one of the body's cells reveal about a person's health? Quite a lot if you can find it. Cedars-Sinai investigators are doing just that.

28 Jan 2026

Scientists Discover Self-Repair Mechanism of Spindle Microtubules

Every second, millions of cells in your body divide in two. In the space of an hour, they duplicate their DNA and grow a web of protein fibers around it called a spindle.

28 Jan 2026

MYC Gene's Dual Role in Cancer Growth and Immune Suppression

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

24 Jan 2026

New Method Designs Highly Active and Stable Enzymes

Enzymes with specific functions are becoming increasingly important in industry, medicine and environmental protection.

24 Jan 2026

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

24 Jan 2026