Biochemistry News and Research

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Cryo-EM Captures Interactions Between BRD4 Bromodomains and Nucleosomal DNA

Researchers have uncovered a new 3D structure of a cancer-linked protein bound to its cellular partner, detailing how it attaches to chromosomes and offering key insights for future disease treatments.

16 Sep 2026

Genetically Modified Bacterial Enzyme Breaks Down Dense Polyurethane Plastics

Your favorite pair of tennies, kicks, or trainers may soon become a little more sustainable. In a study publishing September 11 in the Cell Press journal Chem Catalysis, researchers have developed a new kind of enzyme based on a bacterium found in compost that can degrade the polyurethane material in shoe foams.

12 Sep 2026

New AI Model Unites Protein Sequences and Structures for Evolutionary Insights

An international team of researchers, including Earth-Life Science Institute (ELSI) at the Institute of Science Tokyo, has developed a protein language model that brings together two fundamental sources of information about proteins: their amino acid sequences and their three-dimensional structures.

11 Sep 2026

Research Identifies Microorganisms That Convert Precursors Into Testosterone

Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease often try to reduce testosterone production or block its effects.

7 Sep 2026

New Platform Links Dysfunctional Biomolecular Condensates to Microcephaly and Neurodevelopment

When you add drops of oil to water, the oil and water remain separate. Within cells, biological molecules cluster together in a similar way, separating themselves from the rest of the cell. And while they don't have a membrane, they are their own distinct compartments.

3 Sep 2026

Genetically Engineered Marine Bacteria Accelerate Global Carbon Dioxide Removal Efforts

Rock weathering, the breakdown and dissolving of rocks and minerals caused by their exposure to water, air, and biological life, is a major regulator of Earth's atmospheric CO2 levels and climate.

31 Aug 2026

Biological Germ Cell Development Splits Human Double Chromosome Sets Safely

The body cells of humans and animals contain a double set of chromosomes. One half of the genetic material comes from the mother, the other stems from the father.

25 Aug 2026

New MOSAIC Microscope Captures Biological Processes Across Multiple Scales

Biology doesn’t happen at one scale. Molecular interactions unfold in milliseconds and nanometers, while disease-associated change such as in Alzheimer’s spreads across millimeters of brain tissue.

21 Aug 2026

Powerful Imaging Technique Captures Gene Transcription Inside Living Organisms

All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the molecules responsible for helping build proteins that keep organisms alive.

21 Aug 2026

New Study Reveals How Genetic Mutations Hijack the Parkinson's LRRK2 Switch

Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state.

11 Aug 2026

Uncovering Novel Biomechanical Bacterial Defenses to Optimize Future Antibiotics

A group of Cornell College students and their professor have discovered surprising results in their research on antimicrobial peptides, which are being studied as a method of combating antibiotic resistance.

6 Aug 2026

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

6 Aug 2026

University of Oklahoma Study Uncovers Internal Recycling System in Photoreceptors

For decades, scientists believed that photoreceptors in the retina relied primarily on neighboring support cells, known as the retinal pigment epithelium (RPE), to remove waste. While the RPE is still responsible for clearing away the worn-out tips of photoreceptors each day, new findings from the University of Oklahoma reveal that photoreceptors also perform much of their own internal housekeeping.

30 Jul 2026

Study Reveals How Genome Regulation Changes During Brain Aging

Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's.

24 Jul 2026

Bacterial TGT Enzyme Engages Two tRNAs to Control Protein Production

The enzyme tRNA-guanine transglycosylase (TGT) chemically modifies transfer RNA (tRNA) and plays a key role in how disease-causing bacteria control the production of proteins needed to cause infection. E. coli TGT is nearly identical to the one found in Shigella, which causes the intestinal infection shigellosis.

23 Jul 2026