Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Frog Egg Extracts Illuminate the Untangling Mechanism of DNA Knots

Research reveals how G-quadruplex DNA structures are untangled, highlighting a role for RNA in genome stability and potential cancer therapy strategies.

13 Jun 2025

Unlocking Drug Discovery with SOAR's Innovative Resource

Northwestern's SOAR database enhances drug discovery by mapping gene activity, aiding researchers in identifying treatment targets and understanding diseases.

13 Jun 2025

New Technique Revolutionizing Single-Cell Analysis with Lower Costs and Greater Scale

A new single-cell RNA analysis method, STAMP, significantly reduces costs and biases, allowing for comprehensive profiling of diverse cell populations.

13 Jun 2025

Semaphorin 3E Emerges as a Key Factor in Female Reproduction

The discovery of the Sema3E pathway in ovulation by Cornell researchers could enhance understanding of infertility and improve reproductive health strategies.

13 Jun 2025

Bats Hold Clues to Natural Cancer Resistance

A study to look at why long-lived bats do not get cancer has broken new ground about the biological defenses that resist the disease.

11 Jun 2025

Y Chromosome Loss Weakens Cancer Immunity

When cancer cells in male patients and immune cells in their tumors both lose the Y chromosome, those patients tend to experience poorer outcomes than patients without Y chromosome loss, according to new findings from Cedars-Sinai investigators.

9 Jun 2025

IL-12 Adjuvant Shows Promise in Boosting T-Cell Immunity

Scientists are always searching for new weapons to add to their arsenal in the pursuit of creating vaccinations that would better support the body’s immune system in fending off disease.

9 Jun 2025

New Aging Clock Links Intrinsic Capacity to Immune Health and Longevity

A team of international researchers has developed a new biological age "clock" that estimates how well someone is aging, not just how "old" they or their various organs might be.

5 Jun 2025

PPP2R1A Gene Mutations Improve ATR Inhibitor Drug Effectiveness in Ovarian Clear Cell Cancers

A study in Oncogene shows that PPP2R1A mutations increase sensitivity to ATR inhibitors in ARID1A-mutant ovarian clear cell carcinoma, suggesting a potential biomarker for improved treatment strategies.

5 Jun 2025

Key Factor in Pancreatic Cancer Cell Survival in Distinct Environments

Scientists at the University of California, San Francisco, have found how pancreatic cancer cells grow in the lungs or liver, which are as different from cells as the ocean and the desert are to animals.

4 Jun 2025

How Heterogeneous Antibody Immunity Shapes Strain Evolution

A new study found that person-to-person heterogeneity in antibody immunity influences which influenza (flu) strains dominate in a population.

4 Jun 2025

Gene Editing Using CRISPR and AAV6 Impacts Long-Term Regeneration of Blood Stem Cells

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system.

4 Jun 2025

Study Reveals Key Proteins Behind CAR-T Cell Therapy Effectiveness

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

Canine DNA Reveals New Genes Linked to Gastric Cancer In Humans

Dogs share our homes, our habits and sometimes, our diseases. Gastric cancer is rare in dogs, but when it does strike, it closely resembles gastric cancer in humans: subtle clinical signs, comparable tumor subtypes, late-stage diagnosis and poor outcomes.

3 Jun 2025

Evolution of Cancer Genomes During Metastasis

Research on cancer metastasis uncovers genetic complexities, showing that copy-number alterations play a key role in tumor evolution and treatment resistance.

3 Jun 2025

Light-Controlled Phagobots Offer Precision Immune Modulation

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells.

2 Jun 2025

Exploring the Metabolic Pathways of Cancer Cells

Research from the University of Cincinnati reveals how the MYC oncogene alters PRPS enzymes, impacting redox homeostasis and lymphoma progression.

30 May 2025

UVA Research Reveals Key to HIV Latency

University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly it replicates, and how easily or stubbornly it can reawaken from hiding.

30 May 2025

Study Identifies SMARCB1 and MEOX2 Genes as Growth Regulators of Lung Cancers

A Cancer Gene Therapy study reveals that MEOX2 promotes lung cancer progression while SMARCB1 acts as a tumor suppressor, influencing EGFR expression and response to tyrosine kinase inhibitors.

30 May 2025

Meta-Analysis Identifies Genome-Level Associations of FOXP4 Gene With Long COVID

New genome-wide meta-analysis shows FOXP4 gene variants elevate the risk of long COVID (PASC), linking genetic predisposition to persistent symptoms and lung dysfunction. Findings support tailored treatment approaches.

30 May 2025