Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Microneedle Patches May Unlock Safer, Localized Cancer Immunotherapy

This review highlights the potential of natural polysaccharide microneedles in cancer immunotherapy, focusing on localized treatment and immune activation.

7 Jan 2026

Dual Genetic Mutations Drive RNA Mis-Splicing and Leukemia Progression

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic mutations – IDH2 and SRSF2 – work cooperatively to mis-splice RNA messages and change how blood cells develop.

6 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

LINE-1 Retrotransposons Reshape Cancer Genome Architecture

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

6 Jan 2026

Study Reveals Circadian Control of Immune Variability

In laboratory models, researchers at The University of Texas MD Anderson Cancer Center discovered that a mother's circadian rhythms, or internal body clock, can influence the immune system states of her offspring, which can accurately predict the risk of bacterial infection.

5 Jan 2026

Tumor Bacteria Found to Drive Immunotherapy Resistance

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

5 Jan 2026

Scientists Develop Noise Controller to Tame Random Cell Behavior

Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the answer appears to lie not in genetic differences, but in biological noise - random fluctuations in molecular activity that occur even among genetically identical cells.

5 Jan 2026

New CHANGE-seq-BE Method Sharpens Safety Assessment of CRISPR Base Editors

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital.

5 Jan 2026

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

Avatar Medical transforms CT and MRI scans into interactive 3D models, enhancing understanding for clinicians and patients in surgical planning and education.

5 Jan 2026

Single-Donor Lung-on-Chip Enables Personalized TB Research

Researchers at the Francis Crick Institute and AlveoliX have developed the first human 'lung-on-chip' model using stem cells taken from only one person.

2 Jan 2026

m-RNA and Immunostimulant Activate CAR-Macrophages in Cancer Cells to Fight Cancer

Immune cells (macrophages) capable of combating cancer exist within tumors in the human body, but they are unable to fulfill their functions adequately due to tumor suppression.

2 Jan 2026

Loss of Vitamin C Synthesis Protects Animals From Schistosomiasis

Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have found an advantage to vitamin C deficiency: defense against a significant parasitic disease.

31 Dec 2025

New ddHodge Method Reconstructs Cell Fate Dynamics with High Accuracy

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate. As reported in Nature Communications, this approach paves the way for a deeper understanding of the biological processes involved in development, regeneration, and disease.

30 Dec 2025

Genomic Test Can Accurately Identify Early Recurrence Risk in Prostate Cancer Patients

A new Moffitt Cancer Center study suggests a widely used genomic test can more accurately identify which men with early prostate cancer are at high risk for their disease to come back quickly after treatment, particularly African American men who face the highest burden from this disease.

26 Dec 2025

Engineered EVs Offer a Modular and Clinically Adaptable Immune-Tolerance Platform

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses.

24 Dec 2025

Researchers Find Enzyme That Controls Fat Production, Offering New Drug Target

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD). Rates of these disorders have risen as the world increasingly adopts energy-dense diets and sedentary lifestyles.

24 Dec 2025