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New Double Donut Structure Reveals How SPOP Protein Regulates Cancer

Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap, St. Jude Children's Research Hospital scientists obtained structures of SPOP in both the presence and absence of these mutations.

14 Jul 2026

Prolonged C1 Neuron Activation Causes Heightened Long-Term Panic Behaviors

Anxiety disorders affect more than 300 million people globally. Several brain regions have been linked to anxiety, but how these regions connect has been poorly understood.

11 Jul 2026

Antibody-Based Strategy Makes Stem Cell Transplants Safer

Stem cell transplantation (also called bone marrow transplantation) and gene therapy are among the most powerful curative approaches for blood diseases such as sickle cell disease, b-thalassemia, immune deficiencies, and some blood cancers.

9 Jul 2026

Using Bacteriophages to Treat Inflammatory Bowel Disease

A research team at McMaster University has developed a targeted approach to treating inflammatory bowel disease (IBD) using bacteriophages, viruses that infect specific bacteria, to disarm harmful microbes without disrupting the broader gut ecosystem.

9 Jul 2026

Gut Bacteria Actively Manage Vitamin A Delivery for T Cell Maturation

Scientists at UT Southwestern Medical Center have discovered that gut bacteria help regulate the development of the body's immune system by directing the movement of vitamin A through a previously unrecognized cellular network.

8 Jul 2026

Scientists Identify Biological Link Between Low Birth Weight and Chronic Disease

Researchers have long sought to discover why babies who weigh less than expected at birth, a condition known as small for gestational age, or SGA, are at higher risk for heart, lung and metabolic diseases as adults.

3 Jul 2026

High Stomach Regeneration Rates Can Trigger Tumor Development

Few areas of the body face more daily stress and potential damage than the stomach, which must manage everything we swallow. Along with this constant strain, the stomach also produces acid that can damage its own lining and increase the risk of ulcers.

1 Jul 2026

Single Breast Milk Molecule Reprograms Infant Immune Cells

Trans-vaccenic acid (TVA), the most abundant trans fatty acid found in human breast milk, helps boost immune system development and has long-lasting effects on immune system health in mice, according to a new study by researchers from the University of Chicago.

1 Jul 2026

Open-Source Genomic Tool Accelerates Diagnoses for Rare Diseases

A newly developed open-source tool designed for rigorous reanalysis of genomic data is highly effective at detecting new rare disease diagnoses.

26 Jun 2026

Researchers Discover Molecules Targeting Vital Cell Signaling Proteins

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That's why GPCRs are targeted by roughly one-third of all FDA‑approved drugs.

25 Jun 2026

Modified Mediterranean Diet Improves Lifespan and Metabolic Health

A plant- and fish-based, low-protein diet paired with small amounts of an amino acid commonly found in eggs, meat and dairy increased healthy lifespan and decreased frailty and fat mass in mice, according to a new USC study published today in the journal Cell Metabolism.

24 Jun 2026

Real-Time Molecular Tool Observes Complex Immune System Changes

A lot of things need to go right on a molecular level for immune cells to launch an adaptive response to an infection.

24 Jun 2026

New Research Identifies Gut Fungi as Markers for Food Allergies

Two new studies jointly published in Nature: The Clinical Microbiome reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric allergic diseases - and may be promising targets for new therapies.

24 Jun 2026