Cytokine News and Research

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Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Immune checkpoint inhibitors (ICIs) have transformed cancer care, yet only a subset of patients benefit. A major barrier is tumor microenvironment (TME) heterogeneity: "hot" tumors are enriched with cytotoxic T lymphocytes (CTLs) and respond better, while "cold" tumors lack T-cell infiltration or are shielded by immunosuppressive barriers.

20 Oct 2026

Enzyme Knockdown Repolarizes Immune Cells for Targeted Immunotherapy

Our bodies contain immune cells called macrophages.

8 Oct 2026

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Researchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease.

8 Oct 2026

Chronic Inflammation Linked to Heart Changes and Risks

Chronic inflammation, indicated by GlycA levels, has been linked to heart changes and increased cardiovascular risk, highlighting genetic and environmental interactions.

25 Sep 2026

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

7 Sep 2026

New Research Links Chronic Inflammation to Tumor Microenvironment Epigenetic Changes

Immune checkpoint inhibitors have revolutionized cancer treatment, yet many colorectal tumors remain resistant. Even among patients who initially respond, more than half eventually develop resistance, highlighting the need to better understand how tumors evade immune attack.

19 Aug 2026

Study Reveals Why People Are At Greater Risk of Fungal Infections Than Others

A study on Candida albicans uncovers immune mechanisms that prevent systemic infections, emphasizing the role of IL-1 cytokines and neutrophil response.

13 Aug 2026

Localized Biochemical Halos Shield Pancreatic Beta Cells From Rejection

A protein known as interleukin 10 (IL-10) is the lynchpin of a new method to protect transplanted cells from host immune system aggression.

6 Aug 2026

Mapping Spatial Genome Architecture Unlocks Hidden Biological Mechanisms Behind Genetic Risk

Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome. Instead, they influence genes located far away along the DNA sequence.

5 Aug 2026

Lipid Accumulation in Senescent Brain Cells Drives Aging and Alzheimer’s Disease

A new research paper was published in Volume 18 of Aging on July 1, 2026, titled "Senescent cells accumulate lipid droplets."

17 Jul 2026

Bio-Techne Launches Expanded R&D Systems AI-Engineered Designer Protein Portfolio

Bio-Techne Corporation, a global provider of life science tools, reagents, and diagnostic products, today announced the launch of new additions to its R&D Systems™ AI-Engineered Designer Protein portfolio, designed to improve reproducibility and performance across advanced cell culture and cell therapy development workflows.

From Bio-Techne 8 Jul 2026

Optoelectronic Tweezers Revolutionize Live Cell Screening Without Causing Physical Damage

Single-cell research can reveal cellular heterogeneity, functional diversity, and disease-related mechanisms, making it an important foundation for precision diagnostics, drug development, and personalized therapy.

7 Jul 2026

New 3D Cortical Tissue Models Incorporate Microglia to Bridge Preclinical Translation Gaps

28bio today announced CNS-3D Inflammatory Organoids, designed to evaluate efficacy of anti-inflammatory drugs by quantifying their ability to reduce inflammatory injury, preserve tissue health, and restore neuronal network activity.

20 May 2026

Scientists Design Decoy Peptides to Prevent Chronic Overactivation of Immune Cells

Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important cellular messengers.

19 May 2026

CIPHER-seq Reveals RNA and Protein Activity in Immune Cells

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

9 Apr 2026

Novel ENDOtollins Block Harmful Inflammation While Preserving Infection Response

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

7 Apr 2026

EV Engineering Boosts Drug Delivery and Improves Sepsis Survival

The engineered scaffold protein EN144 significantly improves extracellular vesicle therapies, showing potential in sepsis treatment and targeted drug delivery.

18 Mar 2026

Engineered CD4 CAR T Cells Reduce Amyloid Plaques in Alzheimer’s

Findings suggest engineered CD4+ T cells can modify Alzheimer's pathology and improve CNS immune responses, highlighting a novel therapeutic approach.

19 Feb 2026

Human 3D Model Shows How the Gut Drives Neurodegeneration

Research on a 3D microfluidic model highlights gut-brain interactions, offering new insights into inflammatory processes linked to neurodegenerative diseases.

18 Feb 2026

Gut Bacteria Use Protein Injection to Influence Human Immune System

Bacteria in the human gut can directly deliver proteins into human cells, actively shaping immune responses.

27 Jan 2026