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New Chromosome Packaging Discovery Explains Unlimited Growth in Cancer Cells

Published today in Nature, researchers at the University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center report a previously unrecognized change in how the cell's genetic material is packaged into structures called chromosomes.

4 Jun 2026

How a Tiny Bacterial Enzyme Could Clean Up Chemical Manufacturing

Industrial oxidation chemistry is a cornerstone of modern manufacturing, accounting for nearly one-third of all chemical industrial processes.

3 Jun 2026

Atomic Snapshots of Human SMUG1 Unveil the Secrets of DNA Repair

Researchers have captured the first atomic structures of human SMUG1, an enzyme that helps cells repair damaged DNA.

3 Jun 2026

Cell Phase Separation Creates Droplets That Optimize and Activate Kinase Signaling

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a phenomenon known as phase separation.

2 Jun 2026

Scientists Discover a Metabolic Switch That Regulates Ferroptosis

The loss of an enzyme can reprogram cellular metabolism in a way that protects cells from a specific form of cell death. Paradoxically, the presumed blockade of this enzyme has the opposite effect.

1 Jun 2026

Cornell Researchers Develop Safer CRISPR Technique Using DNA Nicks

Researchers at Cornell University have developed a safer and more precise way to study how genes function in living tissues by refining a recently developed CRISPR-based genetic technique in fruit flies, enabling researchers to better study how genes contribute to development and disease.

28 May 2026

Scientists Reveal How Surface Acids Prevent Bacteria From Blobbing

Researchers have discovered how acids on the surface of bacteria give these microscopic organisms their characteristic "rod" shape-by keeping an enzyme at bay that would otherwise turn the cylindrical cells into shape-shifting blobs.

27 May 2026

Researchers Link Brain Extracellular Matrix Deterioration to Postmenopausal Memory Loss

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

26 May 2026

Study Connects Lysosomal Lipid Movement Directly to Cellular Growth Signaling

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite. Some tumor cells use as much cholesterol as they can access to accelerate their growth beyond the capabilities of normal cells.

25 May 2026

Insects, Microbes, and Food Waste May Be the Answer to the Global Food Crisis

This review examines how minimally processed foods, plant-based alternatives, functional foods, novel protein sources, and food waste valorization could help build healthier and more sustainable food systems. It highlights their potential to improve nutrition, reduce environmental pressures, and strengthen food security, while noting barriers around cost, regulation, safety, labelling, scalability, and consumer acceptance.

19 May 2026

Supercomputer Simulations Map Sodium Pumping in Pathogenic Bacteria

The Na+-NQR enzyme is vital for energy production in pathogenic bacteria like the one that causes cholera, making it a highly promising target for new antibiotics.

15 May 2026

Restricted Interaction Peptides Change Shape to Lock Therapy Inside Solid Tumors

Medications are designed to treat diseased tissues while sparing healthy ones, often by attaching the drug to something that helps guide it directly to its target.

14 May 2026

Study Reveals New Biological Pathway for TNF-Resistant Crohn’s Disease

Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly used therapies.

14 May 2026

Extra Chromosomes Trigger Cellular Changes Linked to Tumor Aggressiveness

One of the biggest challenges in cancer research is understanding why some tumor cells become especially aggressive, invasive and resistant to treatment.

11 May 2026

New CRISPR System Destroys Diseased Cells With High Precision

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched.

8 May 2026

Cryo-EM Images Reveal Coronavirus Proofreading Enzyme in Atomic Detail

The closest-ever detailed look at a key enzyme inside the virus that causes COVID-19 could lead to more effective treatment of the disease.

8 May 2026

Advanced Molecular Blueprints Guide Development Of Next-Generation Malaria Drugs

Researchers from the Universities of Bath and Leeds (UK) have made a significant advance in the fight against malaria by uncovering a promising new potential target for drug discovery.

7 May 2026

Breakthrough CRISPR Discovery Enables Selective Destruction of Cancerous Cells

Among the challenges in treating disease, including cancer, is wiping out malignancies, infection, contaminants or other pathologies, without destroying healthy tissue.

7 May 2026

Metabolic Pathway Loss Makes Cancer Cells Vulnerable to PARP Drugs

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern Medical Center researchers shows.

5 May 2026

New Model Explains How Genetic Information Maintains Cellular Order

A Moffitt Cancer Center researcher has introduced a new model that addresses one of biology's most fundamental questions: How does genetic information keep living systems organized and therefore alive?

5 May 2026