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How Single-Cell Proteomics Could Unlock the Rules That Govern Cells

This review shows how single-cell proteomics by mass spectrometry has advanced from an uncertain idea to a rapidly improving toolkit that can now quantify thousands of protein groups from individual cells. It argues that direct protein measurements, combined with better sample preparation, instrumentation, and multiplexing, could help researchers build more mechanistic models of cell biology while pushing throughput far higher.

13 Apr 2026

AI Predicts Viral Mutations to Design Future-Proof Vaccines

The wave-shaped chart Ratul Chowdhury pulls up on a computer monitor in his office captures the evolutionary cat-and-mouse game his research lab is up against.

13 Apr 2026

Genomic Study Maps the Biosynthesis of Dihydromyricetin in Vine Tea

Vine tea has been consumed in China for centuries and is valued as both a beverage and a medicinal plant.

10 Apr 2026

Evolutionary Atlas Reveals Origin and Diversification of NF-Y Genes

Transcription factors are central to plant biology because they switch genes on and off in response to internal developmental programs and external stress.

9 Apr 2026

Plastisphere Microbes Display Unique Genetic Traits for Survival

Plastic pollution is a global problem. It damages ecosystems, endangers animals, and in the form of nanoplastic particles, can also have consequences for human health.

8 Apr 2026

Breakthrough Platform Could Accelerate Therapeutic Development for Mitochondrial Disorders

Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship-but mitochondria brought some baggage.

7 Apr 2026

Genomic Study Reveals How Bacterial ‘Armor’ Reduces Cholera Disease Severity

Cholera-causing bacteria are locked in an evolutionary arms race with a viral nemesis, according to a new genomic study.

2 Apr 2026

Study Highlights the Vast Untapped Potential Within the Global Protein Universe

The number of known proteins is infinitely small in comparison to the universe of possible proteins which could in theory be realized. Yet these known proteins are the only major training ground for future protein design. Understanding how representative these proteins are of the overall potential diversity can therefore help inform strategies for a wide range of applications, including therapeutic, biocatalysis, or biomaterials development.

31 Mar 2026

Global Experiment Tracks Real-Time Plant Evolution in Changing Climates

For decades, ever since biologists recognized the potential environmental harms from climate change, they have worried that plants will not be able to evolve fast enough to adapt to a rapidly warming planet.

28 Mar 2026

Genetic Study Maps E. coli Capsules Behind Severe Infections

The first large-scale genetic study of E. coli's protective armor has identified the five capsule types that are responsible for 70 per cent of all multidrug-resistant bloodstream infections in Europe.

26 Mar 2026

Study Highlights Hidden Protist Diversity Through Single-Cell Genomics

Researchers from the Earlham Institute, in collaboration with The Department of Biology at the University of Oxford, discovered three previously unrecognised lineages of the protist Bodo, each with its own bacterial endosymbiont (a symbiotic organism living within the body of its host).

23 Mar 2026

Cooperative Microbes Enable Efficient Breakdown of Harmful Plasticizers

Plastic trash has reached the world's most remote locations, from the bottom of the Mariana Trench to the summit of Everest.

19 Mar 2026

New Base Editing Tool Reduces Unwanted DNA Bystander Mutations

The trajectory of base editing has been remarkable, progressing from the laboratory to patient care, treating debilitating or terminal illnesses, in less than a decade.

19 Mar 2026

Study Uncovers How "Selfish Chromosomes" Cheat the Rules of Genetic Inheritance

A new University of Utah-led study has discovered the mechanism behind a decades-old evolutionary mystery-how "selfish chromosomes" cheat the rules of genetic inheritance.

16 Mar 2026

Transposable Elements Found Responsible for Most Lethal Fly Mutations

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University.

11 Mar 2026

Optovolution Uses Light to Guide the Evolution of Dynamic Proteins

Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best.

9 Mar 2026

Study Maps the Complete Genetic Blueprint for Loganin Biosynthesis

Plant-derived terpenoids play essential roles in medicine, agriculture, and human health, but their biosynthesis is often complex and tightly regulated.

5 Mar 2026

Evo 2 AI Model Learns Patterns Across DNA of Life

The DNA foundation model Evo 2, first released in February 2025 as a preprint, is now published in the journal Nature.

5 Mar 2026

3D Reconstructions Reveal Complex Sensory Organ in Ancient Comb Jellies

New 3D reconstructions of a key sensory organ in ctenophores reveal an unexpected structural and functional complexity.

5 Mar 2026

Host-Driven Microbiome Engineering Enhances Soil Health and Plant Resilience

Continuous cropping is widely practiced in horticulture but frequently results in soil degradation, microbial imbalance, and increased disease pressure.

2 Mar 2026