Genome Editing News and Research

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Single-Letter Insertion in Non-Coding DNA can Alter Sex Development in Mice

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice.

11 Apr 2026

New Computational Tools Improve Gene Function Determination Within Fungal Organisms

While RNA sequencing (RNA-seq) has become a standard tool for profiling which genes are active in an organism, determining the actual biological functions of those genes in fungi remains a significant technical challenge. Most existing software tools are designed to cover a broad range of species, often lacking the specificity required for the unique genetic landscape of fungi.

31 Mar 2026

The New Microchip Electrophoresis System MultiNA II MCE-301 - High Sensitivity Detection, Improved Analysis Function and Operability

Shimadzu has recently released the MultiNA II MCE-301 microchip electrophoresis system.

From Shimadzu Europa GmbH 27 Mar 2026

Novel INSTALL Technology Achieves Non-Toxic Gene Integration in Multiple Cell Types

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

12 Mar 2026

Precision Gene Editing Redefines Fruit Color in Polyploid Strawberry

Strawberry fruit color is primarily determined by anthocyanins, pigments synthesized through a tightly regulated metabolic pathway.

24 Feb 2026

Protrusion-Derived EVs Boost Protein Delivery Efficiency

Extracellular vesicles (EVs) are tiny membrane-bound particles released by cells to transport proteins and other molecules to neighboring cells. Because of this natural delivery ability, EVs have attracted growing interest as potential vehicles for therapeutic protein and genome-editing enzyme delivery.

16 Feb 2026

New Gene-Editing Strategy to Eliminate Aggressive Cancer Cells

The initiation and severity of cancer are associated with the atypical behavior of specific genes, referred to as oncogenes. The most recognized of these changes is mutation; however, it is not the sole alteration.

9 Feb 2026

New Map Reveals How Cancer Gene Mutations Influence Tumor Growth

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth.

3 Feb 2026

Replacing Large Mouse Gene Regions with Human DNA

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.

19 Jan 2026

Ancient WUS Genes and Expression Thresholds Shape Shoot Regeneration

Unlike animals, plants generate most organs after embryogenesis through stem cell–driven meristems, enabling lifelong growth and regeneration.

9 Jan 2026

Synthetic Biology and Metabolic Engineering Drive Microbial L-Tryptophan Biomanufacturing

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has driven L-Trp titers to industrially relevant levels while enabling the biosynthesis of downstream products ranging from neurotransmitters and plant hormones to dyes and complex alkaloids.

8 Jan 2026

New CHANGE-seq-BE Method Sharpens Safety Assessment of CRISPR Base Editors

Scientists and physicians can better assess precision genome editing technology using a new method made public today by St. Jude Children's Research Hospital.

5 Jan 2026

Protein MCL1 Emerges as a Central Regulator of Cancer Metabolism

The researchers have succeeded in tracing two classic hallmarks of cancer – the evasion of apoptosis (a form of programmed cell death) and the dysregulation of energy metabolism – back to a common molecular mechanism.

23 Dec 2025

Foreign RsMYB28 Allele Boosts Glucosinolate Accumulation in Rapeseed

These bioactive compounds, found primarily in Brassicaceae plants, play crucial roles in plant defense, contribute to distinctive food flavors, and have potential health benefits, including cancer prevention.

23 Dec 2025

CRISPR Reveals Dark Genome Regions That Sense Cellular Mechanics

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the 'dark genome' that are responsible for controlling how cells sense and respond to the mechanical properties of their local environment.

12 Dec 2025

Neurons and Other Nondividing Cells Respond Differently to CRISPR-Cas9 Gene Editing

The gene editing tool known as CRISPR-Cas9 is changing what's possible for treating a wide range of diseases caused by genetic mutations.

18 Nov 2025

TRV-Mediated Gene Editing System Transforms Tomato Functional Genomics

CRISPR-Cas9 has revolutionized plant genome editing, yet its application in tomato remains limited due to the plant's recalcitrance to transformation and regeneration.

7 Nov 2025

Precision Genome Editing of D3 Gene Enhances Rice Architecture and Stress Resilience

By precisely editing the D3 gene, which regulates both plant height and tillering, researchers developed compact, high-tillering rice plants that maintain grain yield while showing enhanced resistance to bacterial blight.

30 Oct 2025

Study Reveals How TR4 Fungus Silences Banana Defense Genes

Bananas rank among the world's most valuable staple crops, yet their production faces severe losses from Fusarium wilt caused by Fusarium oxysporum f. sp. cubense (Foc) tropical race 4 (TR4).

24 Oct 2025

RNA-Based Molecular Switch Enhances Disease Resistance in Pears

In recent years, scientists have uncovered the remarkable regulatory power of long non-coding RNAs (lncRNAs) - RNA molecules once dismissed as "genetic dark matter."

24 Oct 2025