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Circular Single-Stranded DNA Molecule Can Simultaneously Silence Multiple MicroRNAs

Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen Dong of the Institute of Chemistry, Chinese Academy of Sciences, have collaborated to develop a circular single-stranded DNA molecule capable of simultaneously silencing multiple miRNAs.

4 Dec 2025

Texas A&M Researchers Use AI to Identify a Genetic Time Capsule for Distinguishing Species

In a groundbreaking study, scientists from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) have utilized cutting-edge artificial intelligence methods to identify a region of the X chromosome that has maintained the distinctiveness of mammal species for millions of years.

13 Nov 2025

New Persimmon Genome Assembly Sheds Light on Early Flowering Ability

The genus Diospyros includes over 500 species, among which cultivated persimmon (D. kaki) holds great nutritional and economic importance.

10 Nov 2025

Honeybee Food-Sharing Genes Linked to Human Social Behavior

The study links genetic variation to honeybee sociability, revealing insights into food-sharing behavior and its evolutionary significance in social networks.

25 Sep 2025

Oligo-Barcodes Enable High-Resolution Chromosome Mapping in Tropical Fruits

Karyotype analysis plays a central role in cytogenetics, helping to reveal evolutionary processes and species relationships.

23 Sep 2025

Novel Chromosome Identification System Overcomes Longstanding Bottleneck in Alfalfa Cytogenetics

Karyotype analysis is fundamental to understanding genetic makeup, diversity, and adaptation in plants. Yet, distinguishing individual chromosomes remains challenging in species with small, uniform chromosomes and complex polyploid genomes such as alfalfa.

22 Sep 2025

Built Oral Biofilm Models Reveal How Peri-Implantitis Develops

The study establishes in vitro biofilm models, revealing key insights into dysbiosis in peri-implantitis and paving the way for diagnostic advancements.

12 Sep 2025

Plant Genetics Research Reveals Dynamic and Diverse Centromere Behavior

Cell division is an essential process by which living organisms grow, replenish lost cells, and regenerate dead and damaged tissues.

8 Aug 2025

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a shared pathogenic pathway.

7 Aug 2025

Genetic Mapping Uncovers Six New Species of Glasswing Butterflies

Some butterflies can smell others of the same species, allowing them to identify each other in areas where multiple species all look the same, new research finds.

30 Jul 2025

Advanced Genetic Analysis with the epicGEN Solid Cancer and MSI Kit

Highly sensitive and efficient analysis with an emphasis on specific regions of the genome. epicGEN NGS panels are designed for modern diagnostic laboratories.

29 Jul 2025

Genetically Similar Bacteria Show Unexpected Diversity in Shape and Behavior

Genetically similar bacteria can differ in shape and behavior, even in lab settings. A recent study shows that this variability impacts microbial fitness, virulence, and our understanding of gut microbiota.

26 Jun 2025

Spatial Transcriptomics Reshapes Musculoskeletal Research and Therapy

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

10 Jun 2025

Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development

A new study in Cell reveals that lamina-associated domains (LADs) in early mouse embryos are shaped by dynamic epigenetic pathways, highlighting how histone modifications and chromatin structure guide nuclear architecture during development.

6 May 2025

Guinea Pig Modeling To Study Human Preimplantation and Embryogenesis

Research on guinea pig embryos uncovers similarities to human embryogenesis, advancing understanding of preimplantation stages and reproductive techniques.

23 Apr 2025

DNA Computing Circuits Move Closer to Real-Time Function Inside Living Cells

A comprehensive review titled "From the Test Tube to the Cell: A Homecoming for DNA Computing Circuits?" published Mar. 4 in Intelligent Computing, a Science Partner Journal, highlights progress in operating DNA computing circuits for operation within living cells.

9 Apr 2025

New Chromosome Identification System Revolutionizes Alfalfa Research

In a recent study, scientists have developed a revolutionary chromosome identification system for alfalfa, one of the world's most economically vital forage crops.

19 Mar 2025

Novel Tool Uses DNA Barcode System for Deep-Tissue RNA and Protein Imaging

For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the genome controls development and needed to image hundreds of RNA molecules in a thick tissue sample to understand where and how genes were being expressed in cells.

13 Mar 2025

Novel Expansion Microscopy Technique for Detailed Plant Biomolecule Mapping

The approach to studying plant cells is evolving quite literally due to new research led by Kevin Cox, an Assistant Professor of Biology in Arts & Sciences at Washington University in St. Louis and an Assistant Member of the Donald Danforth Plant Science Center.

10 Mar 2025

Ancient Fish Fossils Reveal Synovial Joints Evolved Millions of Years Earlier Than Thought

Recent research reveals that synovial joints originated in early jawed fish, reshaping our understanding of vertebrate skeletal evolution and movement.

7 Mar 2025