Immune System News and Research

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Johns Hopkins Team Identifies Distinct Subtypes of Senescent Skin Cells

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.

29 Apr 2025

How Bacteria Outsmart Plant Immunity Using a Sugar-Coated Trick

In the intricate world of plant-microbe interactions, plants are continuously defending themselves against invading bacteria. New research highlights the sophisticated strategies these bacterial invaders employ.

23 Apr 2025

Tolerogenic Dendritic Cells in Gut Prevent Allergic Reactions to Food

The immune system must be able to rapidly target invaders such as viruses while avoiding innocuous stimuli, or allergies may develop.

15 Apr 2025

Novel Compound Targets Salmonella's Infection Mechanism

Pathogenic Salmonella strains inject effector proteins into gastrointestinal tract cells, allowing them to infiltrate and grow. Bacteria are often consumed with contaminated food.

15 Apr 2025

Complete Reference Genomes Unlocked for Six Ape Species

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee.

12 Apr 2025

Novel Microscopy Reveals Two-Stage T-Cell Activation During Viral Infection

The research teams led by Wolfgang Kastenmüller and Georg Gasteiger utilized advanced microscopy techniques to investigate the activation and proliferation of specific immune cells, known as T-cells, during viral infections.

11 Apr 2025

QRICH1 Protein Found to Control T Cell Activation in Cancer and Autoimmune Diseases

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

New Research Reveals Mitochondrial Guardians Linked to Parkinson’s and ALS

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria, small organelles, or subunits, within a cell that make and store energy and are found in almost all plants and animals.

8 Apr 2025

Enhanced Oral Vaccination with Competitive Gut Bacteria

Researchers are combining vaccination with targeted colonization of the intestine by innocuous microorganisms to combat bacterial infections. This strategy might signal a sea change in the antibiotic crisis.

4 Apr 2025

CD11c Microglia Play Key Role in Neurodevelopmental Delays from Maternal Inflammation

A research group led by Nagoya University Graduate School of Medicine in Japan has uncovered a potential mechanism linking maternal inflammation to delayed neurodevelopment in infants.

2 Apr 2025

Novel AI Models Enhance Disease Diagnosis and Pathogen Identification

With the widespread availability of AI tools, numerous fields within the technical and natural sciences are experiencing rapid advancements.

1 Apr 2025

Novel Protein Analysis Technique Offers Fresh Insights into Immune System Disorders

A study conducted by researchers at Oregon Health & Science University has revealed a novel mechanism by which proteins can be modified within cells. This finding may have significant implications for the understanding of immune system functionality.

1 Apr 2025

Novel Method Tracks Phagosomal Protein Breakdown, Advancing Disease Research

Researchers at the FAMU-FSU College of Engineering have developed a novel method for investigating protein degradation in immune cells.

28 Mar 2025

CZI Launches Grand Challenge for Revolutionary Imaging Technologies

The Chan Zuckerberg Initiative (CZI) announced a new grand challenge to develop groundbreaking imaging technologies to transform how scientists observe, measure and understand living cells and organisms.

27 Mar 2025

AI Identifies COVID-19 Molecular Mimics Linked to Autoimmune Disease Risk

COVID-19 infection has been associated with an increased risk of autoimmune disorders, such as rheumatoid arthritis and type 1 diabetes.

27 Mar 2025

How B Cells Know When to Mutate—and When to Chill

Study reveals B cells suppress mutations during rapid division, enhancing immune response and offering critical insights for vaccine and treatment development.

27 Mar 2025

Zika and Dengue Virus Use Different Strategies to Infect Dendritic Cells

Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host's dendritic cells.

26 Mar 2025

Fusion Proteins Offer New Path for Antibody Generation in Disease Research

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other antibodies are used by physicians to diagnose conditions or by scientists to advance research projects.

26 Mar 2025

Immune System Peacekeepers Key to Preventing Autoimmunity During Infection

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body.

24 Mar 2025

A Next-Gen CRISPR Tool Just Dropped

Over the past 15 years, developments in the gene-editing technique known as CRISPR-Cas9 have produced significant new understandings of the functions that particular genes play in a variety of disorders.

21 Mar 2025