Immune System News and Research

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Study Overturns Understanding About How T Cells Recognize Lipid Antigens

A new discovery about how cells communicate with each other in the body's immune system has revealed deeper insights for an international team of scientists into fundamental immune system function.

16 Jan 2026

How Cancer Cells Physically Adapt to Survive Within Bodies

Cancer cells that detach from a primary tumor can remain hidden in the body for years in a dormant state, avoiding immune surveillance and waiting until conditions favor the formation of a new tumor elsewhere—a process called metastasis.

16 Jan 2026

Rare EBV-Driven B Cell Event May Spark Multiple Sclerosis Onset

Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

14 Jan 2026

Intelectin-2: A Dual-Action Lectin Fortifies Gut Barrier and Fights Bacteria

The mucosal surfaces that line the body are embedded with defensive molecules that help keep microbes from causing inflammation and infections.

14 Jan 2026

Immune Cell Atlas of Multiple Myeloma Could Guide Future Treatment Strategies

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

12 Jan 2026

Specialized Immune Cells Grown in Labs Offer Hope for Autoimmune Patients

Researchers at the University of British Columbia (UBC) have made a significant discovery regarding the cultivation of specialized immune cells, facilitating the development of readily available off-the-shelf cell therapies aimed at treating cancer, autoimmune diseases, and additional conditions.

9 Jan 2026

Unusual Antibody Tactics Hinder Pathogen Attachment to Cells

Pathogens can create sticky situations. When microbes invade the body to cause an infection, often one of their first lines of attack is to cling tenaciously to the surfaces of targeted human cells.

8 Jan 2026

New Molecules Harness Cellular Recycling to Eliminate Cancer's Immune Shield IDO1

Cells have a remarkable housekeeping system: proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in the cellular recycling machinery.

8 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

Study Reveals Circadian Control of Immune Variability

In laboratory models, researchers at The University of Texas MD Anderson Cancer Center discovered that a mother's circadian rhythms, or internal body clock, can influence the immune system states of her offspring, which can accurately predict the risk of bacterial infection.

5 Jan 2026

Tumor Bacteria Found to Drive Immunotherapy Resistance

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

5 Jan 2026

Engineered EVs Offer a Modular and Clinically Adaptable Immune-Tolerance Platform

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses.

24 Dec 2025

New Rat Study Reveals How Genetic Traits Ripple Through Social Microbiomes

The gut microbiome - made up of trillions of microbes in the digestive tract - is vital for digestion and overall health. Diet and medication shape these microbial ecosystems, but the contribution of genetics has been more difficult to ascertain.

22 Dec 2025

Genes Can Spread Their Effects Through Shared Microbes

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

19 Dec 2025

Innovative mRNA Technology Rejuvenates Aging Immune System in Mice

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that this is possible with an innovative approach.

18 Dec 2025

Visualizing How Cancer Seed Cells Evade Brain Immunity

Metastasis occurs when cancer cells break away from the original tumor and travel through the bloodstream to form new tumors in other parts of the body. It is the leading cause of cancer-related death. Brain metastasis is particularly severe and affects 10-30% of patients with advanced lung, breast, and melanoma cancers.

12 Dec 2025

Researchers Elucidate Microtubule-Mediated Cell Signal Transduction

The most diverse functions of a cell in the human body – from cell division and differentiation to motility and programmed cell death – are controlled by signaling proteins within the cell. This includes the immune system and the reading of genetic information.

11 Dec 2025