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Chaperone-Shielding Mechanism Regulates Protein Glycosylation

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

20 Nov 2025

Newly Identified Mitochondrial DNA Damage Sheds Light on Cellular Stress

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress.

20 Nov 2025

Ultrasound-Controlled Mechanochemical Systems Offer Precision Drug Activation

Conventional drug delivery often relies on passive diffusion or chemical triggers, which may lead to systemic exposure, toxicity, and decreased therapeutic performance.

20 Nov 2025

LEVA Enables Real-Time Tracking of Extracellular Vesicle Communication

In stunning new time-lapse videos, biological nanoparticles scoot and flit across a starry field of glowing dots.

19 Nov 2025

Researchers Reveal How the Brain Forms Hidden-State Inferences

Animals survive in changing and unpredictable environments by not merely responding to new circumstances, but also, like humans, by forming inferences about their surroundings-for instance, squirrels understand that certain bird noises don't signal the presence of a predator, so won't seek shelter when they later hear these same sounds.

18 Nov 2025

Exploring Carotenoid Diversity in Carrots Through Gene Editing

Carrots are rich in carotenoids, essential for human health, providing important compounds like vitamin A.

17 Nov 2025

Reviving Ancient DNA Techniques to Study Historical Disease Evolution

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries.

17 Nov 2025

Breakthrough Microscope Enhances Detection Range for Cellular Observations

Researchers Kohki Horie, Keiichiro Toda, Takuma Nakamura, and Takuro Ideguchi of the University of Tokyo have built a microscope that can detect a signal over an intensity range fourteen times wider than conventional microscopes.

17 Nov 2025

RNA Imaging Predicts Early Cell Damage with High Sensitivity

NIMS, in collaboration with Nagoya University, Gifu University, and the University of Adelaide, has developed a method for simultaneously imaging DNA and RNA inside cells using harmless infrared to near-infrared light.

14 Nov 2025

Studying Disease Evolution Through Ancient DNA Analysis

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries. However, because DNA degrades over time, it is difficult for researchers to analyze DNA samples older than 20 years using conventional analytical approaches.

14 Nov 2025

Texas A&M Researchers Use AI to Identify a Genetic Time Capsule for Distinguishing Species

In a groundbreaking study, scientists from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) have utilized cutting-edge artificial intelligence methods to identify a region of the X chromosome that has maintained the distinctiveness of mammal species for millions of years.

13 Nov 2025

Bacterial Scents Behind Oak Tree Decline May Be Luring Deadly Beetles, Scientists Warn

The deadly decline of Britain’s native oak trees may be driven by an unexpected accomplice: their own smell.

11 Nov 2025

Scientists Reveal Nonenzymatic Role of NUDT5 in Purine Pathway Regulation

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.

7 Nov 2025

Muscle Tissue from a 3D Printer – Produced in Zero Gravity

On their way into space, astronauts' bodies deteriorate dramatically in zero gravity. To address this problem and protect our pioneers in space, researchers are looking for realistic test models.

7 Nov 2025

Using AI and "Protein Language" Models to Speed Monoclonal Antibody Design

Artificial intelligence (AI) and "protein language" models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study led by researchers at Vanderbilt University Medical Center.

6 Nov 2025

Expansion Microscopy Reveals Hidden Architecture of Oceanic Plankton

Plankton are the invisible engines of life on Earth, producing much of the planet's oxygen and forming the foundation of the oceanic food chain.

3 Nov 2025

Frazzled Protein Found to Shape Fast Neural Connections in Fruit Flies

Florida Atlantic University neuroscientists have uncovered a surprising role for a protein named "Frazzled" (known as DCC in mammals) in the nervous system of fruit flies, showing how it helps neurons connect and communicate with lightning speed.

3 Nov 2025

Unexpected Enzyme Strategy Behind Antibiotic Resistance

Researchers at McGill University have identified two enzymes that employ an unprecedented mechanism to provide resistance, thereby introducing a new dimension in the fight against antimicrobial resistance (AMR), which ranks among the top 10 global public health challenges.

31 Oct 2025

Precision Genome Editing of D3 Gene Enhances Rice Architecture and Stress Resilience

By precisely editing the D3 gene, which regulates both plant height and tillering, researchers developed compact, high-tillering rice plants that maintain grain yield while showing enhanced resistance to bacterial blight.

30 Oct 2025

Research Sheds New Light On How Neurons Transmit Strains and Stresses

How do embryos develop? Why does the cortex of the mammalian brain fold? How do we feel touch at our fingertips? These and other fundamental biological questions remain unsolved. Yet, scientists know they all rely on a common principle: the conversion of a physical stimulus into a biochemical signal.

30 Oct 2025