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Advanced 3D Tumor Organoids Reveal How Glioblastoma Responds to Immunotherapy

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

28 Jan 2026

Using a Powerful Technology to Track Body's Most Elusive Proteins

What can a single molecule in just one of the body's cells reveal about a person's health? Quite a lot if you can find it. Cedars-Sinai investigators are doing just that.

28 Jan 2026

Spheroid Shape Predicts Cell Invasion Patterns in Collagen Matrix

As organisms develop from embryos, groups of cells migrate and reshape themselves to form all manner of complex tissues.

27 Jan 2026

Bioengineered Lymphatic Tissue Shows Promise in Treating Secondary Lymphedema

The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes.

27 Jan 2026

AI-Designed CytoTape Records Cellular Events Over Time With High Resolution

Unraveling the mysteries of how biological organisms function begins with understanding the molecular interactions within and across large cell populations.

27 Jan 2026

Prehistoric Genome Pushes Back Origins of Treponemal Diseases in the Americas

Scientists have recovered a genome of Treponema pallidum – the bacterium whose subspecies today are responsible for four treponemal diseases, including syphilis – from 5,500-year-old human remains in Sabana de Bogotá, Colombia.

24 Jan 2026

Coordinated Gene Regulation Drives Saponin Production

Triterpenoid saponins are widely valued for their diverse pharmacological activities and also play important defensive roles in plants.

22 Jan 2026

How Far-Red Light Stops Biofilms in Drug-Resistant Bacteria

Light is a fundamental signal affecting every form of life. Cycles of light and dark help set the biological clocks in organisms from unicellular bacteria to humans.

21 Jan 2026

A Hidden Nanomachine Behind Constant Cellular Secretion

Scientists uncover the tiny machine that delivers essential molecular packages to the cell surface, a fundamental activity for maintaining healthy cells.

19 Jan 2026

How Cancer Cells Physically Adapt to Survive Within Bodies

Cancer cells that detach from a primary tumor can remain hidden in the body for years in a dormant state, avoiding immune surveillance and waiting until conditions favor the formation of a new tumor elsewhere—a process called metastasis.

16 Jan 2026

A Week of 40-Hz Sound Triggers Long-Lasting Amyloid Changes in Monkeys

Forty-hertz auditory stimulation in aged monkeys doubles CSF amyloid-β levels, offering insights into non-invasive strategies for Alzheimer's disease treatment.

15 Jan 2026

Fly Pigmentation Study Uncovers Genes Influencing Dopamine, Sleep, and Movement

Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to conditions like Parkinson's disease, depression and sleep disorders.

14 Jan 2026

Giant Virus with A Massive Genome and Unusual Infection Strategy

Ushikuvirus, a newly identified giant virus, showcases unique cytopathic effects and structural features, enhancing knowledge of viral evolution and diversity.

14 Jan 2026

Mitochondria Transfer Eases Chronic Nerve Pain

For millions living with nerve pain, even a light touch can feel unbearable. Scientists have long suspected that damaged nerve cells falter because their energy factories known as mitochondria don't function properly.

8 Jan 2026

New 3D Model Reveals Crucial Interactions During Early Embryo Development

By engineering a system replicating the womb lining with high biological accuracy, researchers at the Babraham Institute and Stanford University have been able to study the implantation of human embryos, opening up this enigmatic process to investigation.

24 Dec 2025

New vCATCH Method Maps Drug Binding Across Every Cell in the Body

When you take a drug, where in your body does it actually go? For most medications, scientists can make only educated guesses about the answer to this question.

23 Dec 2025

New Rat Study Reveals How Genetic Traits Ripple Through Social Microbiomes

The gut microbiome - made up of trillions of microbes in the digestive tract - is vital for digestion and overall health. Diet and medication shape these microbial ecosystems, but the contribution of genetics has been more difficult to ascertain.

22 Dec 2025

Unveiling the Secrets of Microbial Life on Fresh Lava

Life has a remarkable ability to recover, even in the aftermath of devastating occurrences such as forest fires or volcanic eruptions.

19 Dec 2025

New Method Enables Direct Freezing of iPS Cells in Culture Dishes

With a Kobe University-developed procedure, induced pluripotent stem cells can now be frozen directly in their dishes without losing their viability or undifferentiated state after thawing.

19 Dec 2025

A Molecular Tug-of-War Shapes Gene Regulation and Disease

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

18 Dec 2025