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Study Reveals Pol Theta Role in Cancer DNA Repair

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized.

8 Apr 2026

Novel ENDOtollins Block Harmful Inflammation While Preserving Infection Response

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

7 Apr 2026

Tumors Disable Dendritic Cells by Decreasing Mitochondrial Fitness

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring their energy production can improve immunotherapy.

3 Apr 2026

Molecular Switch AHR Limits Neuron Regeneration and Axon Repair

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

3 Apr 2026

Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

Autism-Associated Genes are Largely the Same Across Different Global Ancestries

A new study, co-led by researchers at the Icahn School of Medicine at Mount Sinai and published March 30 in Nature Medicine, demonstrates that genes associated with autism risk are largely the same across people of different ancestries.

31 Mar 2026

New Platform Models Cancer Metastasis and Cell Cluster Survival

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part because researchers lack reliable ways to recreate the conditions cancer cells encounter as they travel through the bloodstream.

28 Mar 2026

New Skin Atlas Reveals Cellular Diversity Across Body Sites

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body.

26 Mar 2026

Basecamp Research Selects PacBio HiFi Sequencing to Power Trillion Gene Atlas Initiative

PacBio, a leading provider of high-quality, long-read sequencing technologies, today announced that Basecamp Research, a frontier AI lab for therapeutic design, has selected PacBio HiFi sequencing on the Revio® system to generate large-scale environmental and host-associated metagenomic data for the Trillion Gene Atlas—a landmark scientific initiative designed to generate and model biological data at the trillion-gene scale.

From PacBio 23 Mar 2026

Study Uncovers How "Selfish Chromosomes" Cheat the Rules of Genetic Inheritance

A new University of Utah-led study has discovered the mechanism behind a decades-old evolutionary mystery-how "selfish chromosomes" cheat the rules of genetic inheritance.

16 Mar 2026

Study Warns AI Often Predicts Gene Mutations by Looking at Unrelated Traits

New research warns that popular deep learning systems trained for cancer pathology may be relying on hidden shortcuts rather than genuine biological signals.

3 Mar 2026

Structural Blueprint of Cellular Biomolecular Condensates Opens New Therapeutic Possibilities

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes.

26 Feb 2026

Study Reveals New Structural Role for HIV Integrase

The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it.

19 Feb 2026

Genomic Tools Accelerate American Chestnut Restoration Efforts

For more than a century, scientists and conservationists have tried to bring back the American chestnut, a tree once so common it shaped forests across the eastern United States.

16 Feb 2026

Microglia Found to Drive New Neuron Growth in Adult Hippocampus

Breakthrough research from the University of Cincinnati College of Medicine is revealing how immune cells in the adult brain can regulate the generation of new neurons.

10 Feb 2026

DNA Origami Vaccine Scaffolds Sharpen Immune Targeting Against HIV

One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics a virus.

6 Feb 2026

Young Rock Poolers Discover Rare Mediterranean Sea Hare Species on Plymouth Shore

A very unusual marine discovery has been made at Plymouth’s Mount Batten Beach during The Rock Pool Project’s monthly BioBlitz Battle.

4 Feb 2026

Large African Ancestry Genetic Study Reveals Shared Biology Of Schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

24 Jan 2026

Hidden Sperm RNA Remodeling With Age May Impact Next Generation

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown.

21 Jan 2026

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

Avatar Medical transforms CT and MRI scans into interactive 3D models, enhancing understanding for clinicians and patients in surgical planning and education.

5 Jan 2026