Peptides News and Research

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Chemical Tweaks Boost Peptide Stability and Antimicrobial Power

Antibiotic treatments are losing effectiveness against a range of common bacterial pathogens, including E. coli, K. pneumoniae, Salmonella and Acinetobacter, according to a warning issued by the World Health Organization last October.

16 Feb 2026

Artificial Intelligence Enables Stable Intrabody Design in Cells

A new artificial intelligence-driven pipeline developed in a collaborative research combines protein structure prediction, sequence design, and live-cell screening together to enable rapid conversion of antibody sequences into functional intracellular antibodies (intrabodies) that are stable within living cells.

16 Feb 2026

Chemistry Breakthrough Improves Gene Delivery, Reduces Side Effects

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

5 Feb 2026

Sugar Molecules Point to a New Weapon Against Drug-Resistant Bacteria

Australian researchers have developed a powerful new way to target deadly, drug-resistant bacteria by designing antibodies that recognize a sugar found only on bacterial cells – an advance that could underpin a new generation of immunotherapies for multidrug resistant hospital-acquired infections.

4 Feb 2026

Trojan Horse Drug Works in Combination With Copper to Kill Bacteria

A research team at the University of Arizona College of Medicine – Tucson is developing a drug that works in combination with copper to kill bacteria, including those that cause MRSA, a type of staph infection that is resistant to usual treatments.

24 Jan 2026

Engineered EVs Offer a Modular and Clinically Adaptable Immune-Tolerance Platform

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses.

24 Dec 2025

AI-Powered Analysis Reveals How Gene Duplication Drives Plant Development

As global temperatures rise, Cold Spring Harbor Laboratory (CSHL) scientists work to grow stronger, more resilient crops. Yet, this process is challenging.

9 Dec 2025

New Tool Studies Kinase Activity During DNA Damage

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

14 Nov 2025

AI-Powered Approach Boosts Protein Production Efficiency in E. coli

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, including pharmaceuticals, industrial enzymes, and diagnostic antibodies.

29 Oct 2025

New AI Model Unlocks the Therapeutic Potential of Lasso Peptides

In the hunt for new therapeutics for cancer and infectious diseases, lasso peptides prove to be a catch.

17 Oct 2025

PapB Could Make Ozempic-Style Drugs Stronger and Last Longer

Chemistry researchers at the University of Utah have discovered an enzyme referred to as PapB, which is capable of "tying off" therapeutic peptides, drugs resembling proteins, into compact rings, a process termed macrocyclization.

17 Oct 2025

Structural Insights into Heat Shock Chaperone Complex and Protein Handoffs

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's Research Hospital.

15 Oct 2025

Molecular Fossils Offer Fresh Insights into the Dawn of Biology

The questions of how humankind came to be, and whether we are alone in the universe, have captured imaginations for millennia. But to answer these questions, scientists must first understand life itself and how it could have arisen.

24 Sep 2025

Alpha Cells may Produce More Bioactive GLP-1 Than Previously Believed

A new study from Duke University School of Medicine is challenging long-standing views on blood sugar regulation - and pointing to a surprising new ally in the fight against type 2 diabetes.

22 Sep 2025

New Research Shows How Genes Shape Gut Bacteria

Maintaining the abundance and happiness of the good bacteria in our stomachs is a profitable endeavor supported by supplements and fad diets that promise to be the secret to gut health.

12 Sep 2025

Built Oral Biofilm Models Reveal How Peri-Implantitis Develops

The study establishes in vitro biofilm models, revealing key insights into dysbiosis in peri-implantitis and paving the way for diagnostic advancements.

12 Sep 2025

Genes Actively Work to Shape a Healthy Gut Microbiome

New research from the University of Sydney's Charles Perkins Centre has found that genes play an active role in shaping the bacteria found in our gut, questioning the idea that gut health is influenced only by diet.

11 Sep 2025

Targeting the Oral Metagenome to Boost Healthy Bacteria

Professor Zhang, a chemical and biomolecular engineering professor at UC Berkeley, is working to distinguish between the healthy and unhealthy bacteria in the human mouth. Her goal is to promote a probiotic oral microbiome by increasing the population of beneficial bacteria.

5 Sep 2025

AI Tool for Designing Antibiotics from Scratch

In a recent Cell Biomaterials study, University of Pennsylvania researchers offer AMP-Diffusion, a generative AI tool for creating tens of thousands of novel antimicrobial peptides (AMPs) — short strings of amino acids that serve as the building blocks of proteins — with bacteria-killing capability.

3 Sep 2025

Breakthrough Research Reveals Pathway to Early Protein Synthesis

Chemists at UCL have shown how two of biology's most fundamental ingredients, RNA (ribonucleic acid) and amino acids, could have spontaneously joined together at the origin of life four billion years ago.

28 Aug 2025