Peptides News and Research

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AI-Powered Approach Boosts Protein Production Efficiency in E. coli

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, including pharmaceuticals, industrial enzymes, and diagnostic antibodies.

29 Oct 2025

New AI Model Unlocks the Therapeutic Potential of Lasso Peptides

In the hunt for new therapeutics for cancer and infectious diseases, lasso peptides prove to be a catch.

17 Oct 2025

PapB Could Make Ozempic-Style Drugs Stronger and Last Longer

Chemistry researchers at the University of Utah have discovered an enzyme referred to as PapB, which is capable of "tying off" therapeutic peptides, drugs resembling proteins, into compact rings, a process termed macrocyclization.

17 Oct 2025

Structural Insights into Heat Shock Chaperone Complex and Protein Handoffs

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's Research Hospital.

15 Oct 2025

Molecular Fossils Offer Fresh Insights into the Dawn of Biology

The questions of how humankind came to be, and whether we are alone in the universe, have captured imaginations for millennia. But to answer these questions, scientists must first understand life itself and how it could have arisen.

24 Sep 2025

Alpha Cells may Produce More Bioactive GLP-1 Than Previously Believed

A new study from Duke University School of Medicine is challenging long-standing views on blood sugar regulation - and pointing to a surprising new ally in the fight against type 2 diabetes.

22 Sep 2025

New Research Shows How Genes Shape Gut Bacteria

Maintaining the abundance and happiness of the good bacteria in our stomachs is a profitable endeavor supported by supplements and fad diets that promise to be the secret to gut health.

12 Sep 2025

Built Oral Biofilm Models Reveal How Peri-Implantitis Develops

The study establishes in vitro biofilm models, revealing key insights into dysbiosis in peri-implantitis and paving the way for diagnostic advancements.

12 Sep 2025

Genes Actively Work to Shape a Healthy Gut Microbiome

New research from the University of Sydney's Charles Perkins Centre has found that genes play an active role in shaping the bacteria found in our gut, questioning the idea that gut health is influenced only by diet.

11 Sep 2025

Targeting the Oral Metagenome to Boost Healthy Bacteria

Professor Zhang, a chemical and biomolecular engineering professor at UC Berkeley, is working to distinguish between the healthy and unhealthy bacteria in the human mouth. Her goal is to promote a probiotic oral microbiome by increasing the population of beneficial bacteria.

5 Sep 2025

AI Tool for Designing Antibiotics from Scratch

In a recent Cell Biomaterials study, University of Pennsylvania researchers offer AMP-Diffusion, a generative AI tool for creating tens of thousands of novel antimicrobial peptides (AMPs) — short strings of amino acids that serve as the building blocks of proteins — with bacteria-killing capability.

3 Sep 2025

Breakthrough Research Reveals Pathway to Early Protein Synthesis

Chemists at UCL have shown how two of biology's most fundamental ingredients, RNA (ribonucleic acid) and amino acids, could have spontaneously joined together at the origin of life four billion years ago.

28 Aug 2025

Belgian Scientists Reveal How Dendritic Cells Respond to Lipid Nanoparticles

Belgian scientists have uncovered new details about how the immune system responds to vaccines. Dendritic cells, which are key immune messengers that help kick-start the body's defenses, show specific responses to lipid nanoparticles.

27 Aug 2025

Simple Peptides Mimic Natural Protein Protection to Revolutionize Biomolecule Stability

A new study from researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) reveals that extremely simple peptides can mimic a biological process that protects sensitive proteins from environmental stress.

6 Aug 2025

AI-Designed Proteins Offer New Hope for Personalized Cancer Immunotherapy

Precision cancer treatment on a larger scale is moving closer after researchers have developed an AI platform that can tailor protein components and arm the patient's immune cells to fight cancer.

29 Jul 2025

AI-Driven Precision for Next-Gen Cancer Immunotherapy

Consider how immune cells may be tailored to combat any type of cancer. T cell receptor (TCR) therapy has the potential to become the standard cancer treatment.

29 Jul 2025

Researchers Uncover Complex Substrate Profile for Enzyme Action

Research on γ-secretase reveals its unique substrate recognition mechanism, offering potential for developing precise therapeutic agents for various diseases.

14 Jul 2025

New Software Boosts Genome Editing Accuracy for Genetic Therapies

This innovative software, CRISPRware, optimizes guide RNA design for genome editing, supporting research on genetic disorders and uncharacterized peptides.

9 Jul 2025

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

Novel Peptide Shows Promise in Fighting Deadly, Drug-Resistant Bacteria

A study identifies a new antimicrobial peptide that effectively targets gram-negative bacteria, highlighting its potential in combating antibiotic resistance.

5 Jun 2025