Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

Powdery mildew is among the most widespread crop diseases, affecting cereals, grapes, cucurbits, tomatoes, fruit crops, and ornamentals in fields and greenhouses.

5 Aug 2026

Female Hearts Rely on Molecular Safeguard to Avoid Failure

Men and women are not born with the same risk of heart disease, and for decades scientists have struggled to explain why. A new study from the University of North Carolina at Chapel Hill, published in Genes & Development, offers a striking answer: the female heart depends on a molecular safeguard that the male heart can largely do without - and when that safeguard is removed, female hearts fail while male hearts keep beating.

20 Jul 2026

Crucial X Chromosome Protein Protects Female Hearts From Fatal Failure

Men and women are not born with the same risk of heart disease, and for decades scientists have struggled to explain why.

17 Jul 2026

Merck KGaA, Darmstadt, Germany, Agrees to Acquire Bio-Techne, Strengthening Leadership Position in Fast-Growing Life Sciences Markets

Merck KGaA, Darmstadt, Germany, a leading science and technology company, and Bio-Techne Corporation, a Minneapolis-based global provider of life science tools, analytical technologies, and consumables, today entered into a definitive agreement pursuant to which Merck KGaA, Darmstadt, Germany, will, subject to customary closing conditions, acquire Bio-Techne for US$73 per share in cash, representing a total enterprise value of approximately US$11.3 billion (EUR 9.9 billion), a 36% premium to Bio-Techne's one-month volume weighted average trading price.

From Bio-Techne 26 Jun 2026

Decoding Hidden Metabolic Tissue Crosstalk via Advanced Proteomic Tracking

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these messages to organs throughout the body.

23 Jun 2026

Declining Autophagy in Aging Females Compromises Vital Early Embryonic Development

AMA significantly impairs female fertility and reduces the success of assisted reproductive technology (ART) by compromising early embryonic development.

13 Jun 2026

Study Reveals Mitochondria Plug Straight Into the Nuclear Command

For generations, textbooks have taught that a cell's energy simply drifts to wherever it is needed.

11 Jun 2026

Researchers Outline Dynamic Protein Control Systems for Better Clinical Decisions

Cancer has often been explained through mutations in deoxyribonucleic acid (DNA) or changes in ribonucleic acid (RNA), but these layers do not fully explain why tumors with similar genetic profiles can behave differently.

10 Jun 2026

Study Shows How AI and Single Cell Science are Changing Modern Medicine

Recent technological advances have pushed the boundaries of cellular biology far beyond what was conceivable even decades ago

4 Jun 2026

Evosep and Molecular You Announce Strategic Collaboration to Scale Standardized Multi-Omic Testing Globally

Evosep and Molecular You today announced a strategic collaboration to advance standardized, high-throughput multi-omic testing for personalized biomarker profiling.

From Evosep 3 Jun 2026

Introducing Evosep Proteomics to Standardize and Scale Proteomics for Research and Drug Development

Evosep announces the launch of Evosep Proteomics, an ecosystem designed to standardize and scale LC-MS-based proteomics for research and pharmaceutical drug development.

From Evosep 2 Jun 2026

Advances in Proteomics Accelerate Precision Oncology and Biomarker Discovery

A recent review shows that proteomics-driven multi-omics integration reveals tumor heterogeneity and functional regulatory networks beyond genomic information, facilitating the discovery of clinically relevant biomarkers and therapeutic targets.

28 Apr 2026

Protein Shape Changes Come Into Focus With LiP-MS and 3D Proteomics

This review explains how LiP-MS detects protein structural changes across whole proteomes, adding functional insight that standard abundance-based proteomics often misses. It also surveys method variants and shows how LiP-MS supports drug-target discovery, disease biomarker research, and the broader framework of “3D proteomics.”

20 Apr 2026

Next-Generation Mass Spectrometry Reveals How DIA Deepens Proteome Coverage

A multivendor comparison in a neonatal mouse model of bronchopulmonary dysplasia found that DIA, especially on next-generation platforms such as Orbitrap Astral and timsTOF Ultra, greatly expanded peptide and protein detection while preserving broad biological concordance. The deeper coverage improved subcellular and pathway annotation, increased differential protein detection, and reduced estimated sample-size needs, although platform-specific technical differences still complicated direct comparisons.

19 Apr 2026

How Mitochondrial Damage Accelerates Stem Cell Aging

Hematopoietic stem cells (HSCs), the cells that produce all blood cell types, start to lose their efficacy as one ages, which eventually reduces the ability to maintain healthy blood and a robust immune system.

17 Apr 2026

How Single-Cell Proteomics Could Unlock the Rules That Govern Cells

This review shows how single-cell proteomics by mass spectrometry has advanced from an uncertain idea to a rapidly improving toolkit that can now quantify thousands of protein groups from individual cells. It argues that direct protein measurements, combined with better sample preparation, instrumentation, and multiplexing, could help researchers build more mechanistic models of cell biology while pushing throughput far higher.

13 Apr 2026

Janelia Scientists Develop New Method To Study Blood-Brain Barrier Proteins

Think it was hard to get into Studio 54? Try getting through the blood-brain barrier.

10 Apr 2026

A Python-Inspired Molecule Suppresses Appetite After Eating

The study identifies pTOS as a key metabolite in appetite suppression, highlighting a gut–liver–brain pathway with implications for obesity therapy.

2 Apr 2026

Newly Discovered CRISPR System Activates Genes Without Cutting DNA

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR gene-editing systems that merely find and cut DNA.

26 Mar 2026

New PanNDA Atlas Maps Protein Networks in Neurodegenerative Diseases

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's Research Hospital scientists developed the pan-neurodegeneration atlas (PanNDA).

24 Mar 2026