RNA Sequencing News and Research

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CIPHER-seq Reveals RNA and Protein Activity in Immune Cells

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

9 Apr 2026

RNU2-2 Variants Drive Most Common Recessive Neurodevelopmental Disorder

New findings on RNU2-2 syndrome highlight its role in neurodevelopmental disorders, emphasizing genetic counseling and early diagnosis for affected families.

9 Apr 2026

Plasmidsaurus Accelerates RNA-Seq: New EU Hub and Genovis Partnership Adds Stability to Speed, Without the Ice

Plasmidsaurus, the leading Sequencing as a Service company, has announced two transformative evolutions of its RNA-Seq ecosystem: the launch of a high-capacity RNA sequencing hub in Cologne, Germany, and a global partnership with Genovis to release SEQguard™ Dino Preserve, an RNA preservation solution that enables ambient shipping of purified RNA samples for sequencing.

From Plasmidsaurus Inc. 3 Apr 2026

Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

New Computational Tools Improve Gene Function Determination Within Fungal Organisms

While RNA sequencing (RNA-seq) has become a standard tool for profiling which genes are active in an organism, determining the actual biological functions of those genes in fungi remains a significant technical challenge. Most existing software tools are designed to cover a broad range of species, often lacking the specificity required for the unique genetic landscape of fungi.

31 Mar 2026

Identifying the Cellular Origin of MS-Related Neuroinflammation

Signals from the gut have been linked to autoimmune inflammation, but fundamental cellular processes remain poorly understood.

30 Mar 2026

Genetic Analysis Reveals Why Haploid Fish Embryos Fail to Survive

Naturally occurring haploids are predominantly documented in plants; the first report dates to 1923, when haploid individuals were identified in the Jimson Weed.

27 Mar 2026

SLIT3 Protein Drives Brown Fat Activation Through Dual Signaling

Researchers have determined how a key protein activates brown fat by expanding blood vessels and nerves in the heat-generating tissue.

26 Mar 2026

Capsule Technology Enables Multi-Step Analysis of Individual Living Cells

Researchers have developed a capsule-based method that makes it possible to analyze the same cell through multiple experimental steps.

13 Mar 2026

New Method Reveals How Tumors Rewire Genetic Splicing Programs

Cancer is caused by faulty genes, but what also shapes a cancer cell's behaviour is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive.

13 Mar 2026

Gut Microbes Reshape Ovarian Aging in Mice

Findings indicate gut microbes impact ovarian function in mice, offering insights into reproductive aging and potential microbiome-based health interventions.

12 Mar 2026

Scientists Develop Novel Tool to Profile Elusive HIV Reservoir Cells

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and transmission.

4 Mar 2026

T Immune Cell Transcriptomic Clock Measures Aging in Specific Immune Cells

A new research paper was published in Volume 18 of Aging-US on February 8, 2026, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV."

20 Feb 2026

Scientists Map Protein Production Across Individual Brain Cells

The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time.

19 Feb 2026

Microglia Found to Drive New Neuron Growth in Adult Hippocampus

Breakthrough research from the University of Cincinnati College of Medicine is revealing how immune cells in the adult brain can regulate the generation of new neurons.

10 Feb 2026

Aged Neutrophils With CCL3 Drive Tumor Growth Across Cancers

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the microenvironment of tumors, where they and other immune cells play opposing and frequently mutable roles in promoting-or resisting-cancer progression.

6 Feb 2026

Hidden Sperm RNA Remodeling With Age May Impact Next Generation

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown.

21 Jan 2026

Immune Cell Atlas of Multiple Myeloma Could Guide Future Treatment Strategies

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

12 Jan 2026

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

8 Jan 2026

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026