RNA Sequencing News and Research

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New Method Discovers Genetic Switches More Quickly

Researchers led by Dubravka Vučićević at the Max Delbrück Center have developed a new method for discovering how DNA controls genes. Published in “Cell Genomics,” their technique can reveal the genetic “switches” that regulate important genes more quickly than existing methods.

10 Sep 2025

spVelo: A New Method for Integrating Spatial and Temporal Data in RNA Velocity Analysis

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it will be and its function.

8 Sep 2025

RNAConnect® Announces Commercial Launch of UltraMarathonRT® cDNA Synthesis and Amplification Kit for Enhanced Short-Read RNA Sequencing

RNAConnect, a leader in next-generation molecular biology tools, today announced the commercial launch of the UltraMarathonRT cDNA Synthesis and Amplification Kit, designed to elevate short-read RNA sequencing workflows.

3 Sep 2025

Genetic On-Off Switch for Cilia Formation Uncovered

Some might say it looks like a finger. Others might see a worm. Scientists in the field often liken it to an antenna. The technical name is primary cilium.

2 Sep 2025

Cornell Study Reveals Early Genetic Differences Between Male and Female Embryos

Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization.

1 Sep 2025

Researchers Uncover Toggle Switch Guiding Stem Cell Fate in Olfactory Neurons

Cellular differentiation of stem cells into specialized cells requires many steps, including division, to create more cells; fate determination, which is a commitment to a specific lineage or developmental path; and migration, to integrate the cell into its final location.

29 Aug 2025

Bacteria Pass Down Environmental Memories Across Generations

Bacteria aren't just mindless microbes. New research from the Hebrew University of Jerusalem reveals that single bacterial cells can carry a "memory" of their past environments-passing it down through generations-before eventually forgetting.

27 Aug 2025

Scientists Use Single-Cell Proteomics to Track Blood Cell Differentiation

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through the course of health or disease.

25 Aug 2025

Genetic Insights from Wild Crop Relatives may Help Secure Future Food Supplies

With climate change and more frequent extreme weather events, researchers predict that global yields of important crops like maize, rice, and soybeans could decline by 12 to 20% by the end of the century.

22 Aug 2025

Salk Researchers Create First Genetic Atlas to Span the Entire Arabidopsis Life Cycle

Nearly everything you know about plants was first discovered in a plant you've likely never heard of. Arabidopsis thaliana, also known as thale cress, is a small, flowering weed that has shaped much of plant biology as we know it.

20 Aug 2025

Breaking Down the Evolutionary Puzzle of the Chaetognath

In a new Nature study, the genomic, epigenomic, and cell-level characteristics of the mysterious arrow worm have been tied together.

19 Aug 2025

Missing Microexons Disrupt Synapse-Related Proteins in Pediatric Glioma

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

19 Aug 2025

Researchers Uncover How Macrophages Respond to Infection Stress

Fighting infections requires speed and accuracy. A team of researchers from CeMM and MedUni Vienna, led by Christoph Bock and Matthias Farlik, explored how macrophages—the body’s initial responders—handle this stress.

11 Aug 2025

New RNA Sequencing Technology Uncovers Molecular Drivers of Cellular Differentiation

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation that could lead to better regenerative therapies.

8 Aug 2025

AI Tool Accelerates Hunt for Elusive Genome‐Encoded Microproteins

Proteins sustain life as we know it, serving many important structural and functional roles throughout the body.

1 Aug 2025

Blocking TG2 Could Help Immune Cells Attack Ovarian Tumors

The study reveals TG2's role in ovarian cancer metastasis, suggesting that its inhibition could re-educate the immune system for better anti-tumor efficacy.

30 Jul 2025

Scientists Uncover How New Genes Are Switched On in Fruit Flies

Most genes are ancient and shared across species. But a small subset of genes are relative newcomers, spontaneously emerging from stretches of DNA that once encoded nothing at all.

14 Jul 2025

New Cellular Signature Reveals Why Some Prostate Cancers Resist Standard Treatment

A new study from University of Michigan Rogel Cancer Center researchers identifies a cellular signature that explains why about one-third of prostate cancers respond especially poorly to treatment.

9 Jul 2025

Reactivating a Genetic Switch Restores Ear Regeneration in Mice

By flipping an evolutionarily disabled genetic switch involved in Vitamin A metabolism, researchers have enabled ear tissue regeneration in mice. Unlike some animals such as fish and salamanders, mammals have limited capacity to regenerate damaged tissues or organs fully.

27 Jun 2025

Worm Species Reveal Deep Genetic Similarities Across Evolutionary Time

Two species of worms, separated by 20 million years of evolution, have been found to activate their genes in nearly identical ways as they develop from a single cell to a fully formed organism.

27 Jun 2025