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Aged Neutrophils With CCL3 Drive Tumor Growth Across Cancers

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the microenvironment of tumors, where they and other immune cells play opposing and frequently mutable roles in promoting-or resisting-cancer progression.

6 Feb 2026

Hidden Sperm RNA Remodeling With Age May Impact Next Generation

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown.

21 Jan 2026

Immune Cell Atlas of Multiple Myeloma Could Guide Future Treatment Strategies

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

12 Jan 2026

USU Researchers Discover CRISPR Cas12a3's Potential for Viral Protein Inhibition

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to disable and modify genes, heading off infections at the (cellular) pass.

8 Jan 2026

Turning Human Fat into Insulin-Producing Organoids That Reverse Diabetes

By preserving fat tissue architecture, researchers created organoids that restore insulin function, paving the way for advancements in diabetes treatment.

8 Jan 2026

Aging Alters a Common Set of RNA Splicing and Processing Genes Across Tissues

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues."

6 Jan 2026

New ddHodge Method Reconstructs Cell Fate Dynamics with High Accuracy

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate. As reported in Nature Communications, this approach paves the way for a deeper understanding of the biological processes involved in development, regeneration, and disease.

30 Dec 2025

Researchers Uncover Gene Control Elements Tied to Alzheimer’s Disease

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral quirks, and keep our cells and organs running.

19 Dec 2025

RNAConnect Launches the UltraMarathonRT Direct RNA‑Seq Kit to Advance Nanopore-Based Native RNA Sequencing

RNAConnect, a life science company providing next generation tools to the RNA community, today announced the commercial availability of the UltraMarathonRT® Direct RNA‑Seq (uMRT DRS) Kit, a native‑RNA library preparation solution for Oxford Nanopore Technologies® direct RNA sequencing (SQK-RNA004).

From RNAConnect 17 Dec 2025

Mitochondrial Supercomplex Protein COX7RP Extends Lifespan and Healthspan

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.

11 Dec 2025

How Tumor Stem Cells Hijack Neutrophils to Evade Immunotherapy

Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors.

9 Dec 2025

Broken DNA Loops Trigger Lymphoma Development

Cancer involves more than just genetic mutations; it also involves structural failures. Consider a city where roads disappear, isolating communities from vital resources.

8 Dec 2025

Study Exposes Ancestry Biases in Current Gene Annotations

Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ancestry, according to a study published today in Nature Communications.

4 Dec 2025

New Insight Into Light-Guided Growth of Bristleworm Eyes

A new study, led by the University of Vienna and the Alfred Wegener Institute in Bremerhaven, shows how the eyes of adult marine bristleworms continue to grow throughout life – driven by a ring of neural stem cells reminiscent of vertebrate eyes.

2 Dec 2025

Discovery Reveals Unexpected Role for OTULIN in Controlling Tau Expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

26 Nov 2025

CellWhisperer Enables Natural Language Exploration of Single-Cell Biology

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

12 Nov 2025

New Persimmon Genome Assembly Sheds Light on Early Flowering Ability

The genus Diospyros includes over 500 species, among which cultivated persimmon (D. kaki) holds great nutritional and economic importance.

10 Nov 2025

Dual Role of SlNOR and SlNOR-like1 Revealed in Tomato Pollen Development

Successful fertilization in flowering plants depends on healthy pollen development and structural integrity of the pollen wall.

10 Nov 2025

RNA Molecules Alter Genome Structure to Silence Critical Neuronal Genes During Stress

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

5 Nov 2025