Schizophrenia News and Research

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Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

How Feedback Mechanisms Control Neural Chaos for Stable Visual Processing

What we see appears stable, even though neuronal activity is full of irregular fluctuations. A team led by Dr Mehdi Borjkhani from ICTER has shown, using a minimal model of the primary visual cortex, that two natural feedback mechanisms can constrain chaos and reduce variability in neural activity by up to 93 percent.

23 Sep 2026

Study Links Maternal Infections to Fetal Brain Development

Research shows maternal infections affect fetal brain development, with immune responses linked to autism spectrum disorder and other neurodevelopmental issues.

18 Sep 2026

Noninvasive Imaging Framework Enhances Predictions of Higher-Order Human Brain Function

Researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have developed a new, noninvasive way to examine how blood flow and cellular organization align across the layers of the living human brain.

17 Sep 2026

Scientists Grow Human Brain Organoids in Cortex-Depleted Mice

Stanford Medicine scientists have chalked up a major advance in growing human brain cells outside of the human brain - and outside of laboratory glassware.

17 Sep 2026

Hidden DNA Sequences Outside Human Genes Contain Signatures of Complex Schizophrenia

Researchers at the University of Oslo have mapped which parts of our DNA carry the inherited differences behind complex traits and disorders.

15 Sep 2026

New Understanding of Brain Circuitry Genes Opens Door for Targeted OCD Therapies

A Rutgers-led international team co-authored a study, which was published in Nature Neuroscience, revealing 36 genes significantly increasing the risk for obsessive-compulsive disorder (OCD) and chronic tic disorders. This research offers the most comprehensive biological insight into the development of these conditions and potential future treatments.

4 Sep 2026

Centriolar Satellites Coordinate Crucial Internal Cellular Protein Trafficking Networks

Inside every cell, thousands of proteins must reach the right place at the right time. Helping coordinate this complex logistics network are centriolar satellites-tiny, membrane-less organelles that play important roles in protein trafficking, cell division, and the formation of cilia.

22 Aug 2026

Locally Activated Skull T Cells Halt Glioblastoma Growth in Mice

Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as rapid first responders against brain cancer before distant lymph nodes get the signal that abnormal cells are present.

20 Aug 2026

Scientists Discover How Brain Cells Overcome the Effects of a Disease-Causing Genetic Deletion

Scientists at the Fralin Biomedical Research Institute at VTC have discovered how an experimental therapy can help brain cells overcome the effects of a disease-causing genetic deletion.

29 Jul 2026

New Framework Uses Genetic Variant Data to Recall Biobank Participants

Clinical biobanks that combine genomic data with electronic health records (EHRs) have become powerful resources for discovering genetic variants associated with disease.

28 Jul 2026

Sleep helps neural networks recover adaptive performance after absorbing daily life shocks

Every animal that has ever been studied closely, from the fruit fly to the philosopher, surrenders each day to a state that looks, from the outside, like a small rehearsal for death.

1 Jul 2026

Scientists Move Beyond Individual Genes to Decode Schizophrenia’s Complex Genetic Network

Scientists have long known that schizophrenia runs in families, but pinpointing exactly which genes contribute to risk has been like searching for needles in a haystack. Now, researchers at the Lieber Institute for Brain Development and a consortium of collaborators from the University of Bari, Italy, and over 60 psychiatric hospitals all over the world, have developed a groundbreaking approach that looks beyond individual genes.

23 Jun 2026

Scientists Identify Brain Structure Responsible for Filtering Self-Generated Sensory Noise

In the split second after you hear a noise, your brain is already making a potentially life-or-death deduction.

13 Jun 2026

Live-Imaging Techniques Reveal How Stem Cells Collectively Suppress Tumors

It all starts with a single cell.

2 Jun 2026

Researchers Identify Neural Pathway Governing Memory Organization

When a person has a new experience, their brain faces a subtle but critical decision: should this experience be categorized with other stored memories, or should it be filed away as its own new memory? Getting it right allows the brain to help people navigate the world.

28 May 2026

Analysis Reveals Blurred Neural Patterns During Failed Cognitive Switches

Most people have experienced the feeling: switching from one task to another, only to find the brain momentarily stuck in the old mode of thinking. Sometimes, even after realizing a strategy no longer works, the mind keeps returning to it anyway.

21 May 2026

Researchers Compare Embryonic and Adult Mouse Brain Targets to Map Memory Networks

A peer-reviewed invited review published today in Genomic Psychiatry argues that the adult brain, when it learns and remembers and rewires, is not inventing something new.

20 May 2026

Epigenetic Changes May Influence Inheritance Beyond DNA Sequence Alone

When we think about genetic inheritance, we usually leap to DNA, the four-letter code containing the instructions for building a living organism.

11 May 2026

Interactions Across the Genome Drive Neurodevelopmental Risks

People who have the same deletion of a section of chromosome 16 are susceptible to neurodevelopmental disorders; however, some may simply show moderate psychological symptoms like anxiety or depression, while others may have significant intellectual disability or developmental delay.

6 May 2026

Brain Discovery Links Interhemispheric Communication to Spatial Memory

A team led by the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has identified a brain circuit essential for spatial memory.

15 Apr 2026