Schizophrenia News and Research

RSS

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Lab-Grown Brain Tissue Masters a Classic Computing Benchmark

Imagine balancing a ruler upright in the palm of the hand: There is a need to continually pay attention to the angle of the ruler and make several little changes to ensure it does not topple over.

20 Feb 2026

Large African Ancestry Genetic Study Reveals Shared Biology Of Schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

24 Jan 2026

Decoding the Molecular Logic of Histamine Signaling in the Brain

Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other immune responses.

19 Jan 2026

Fly Pigmentation Study Uncovers Genes Influencing Dopamine, Sleep, and Movement

Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to conditions like Parkinson's disease, depression and sleep disorders.

14 Jan 2026

Gut Microbiome Plays a Direct Role in Shaping Brain Function and Evolution

A groundbreaking new study reveals that changes to the gut microbiome can change the way the brain works.

6 Jan 2026

New Method Turns Glial Cells Directly Into Parvalbumin Neurons

Parvalbumin cells play a central role in keeping brain activity in equilibrium. They control nervcell signaling, reduce overactivity and make sure that the brain is working to a rhythm.

5 Jan 2026

Homer1 Gene Plays a Critical Role in Shaping Attention

Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise.

26 Dec 2025

Changes in the Activity of KCC2 Protein Influence Reward Learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

11 Dec 2025

Researchers Uncover How Methamphetamine Suppresses Dopamine Clearance

Dopamine brings on a surge of pleasure, but too much dopamine in a synapse can ultimately lead to mood disorders and addiction.

26 Nov 2025

Researchers Reveal How the Brain Forms Hidden-State Inferences

Animals survive in changing and unpredictable environments by not merely responding to new circumstances, but also, like humans, by forming inferences about their surroundings-for instance, squirrels understand that certain bird noises don't signal the presence of a predator, so won't seek shelter when they later hear these same sounds.

18 Nov 2025

Understanding Genetic Diversity Through Short Tandem Repeats

Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that could help explain why people experience disease differently, and why some treatments work better for certain populations.

17 Nov 2025

Oxidative Stress May Hold Clues to the Origins of Repetitive Behaviors

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published November 5, 2025, in the open-access journal PLOS One by Kendall Coden and Dr. Joseph Garner of Stanford University, U.S.

6 Nov 2025

New Insights into rRNA Motifs and Nervous System Genes

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell's protein-making machinery. rRNA accounts for much of the RNA in a cell, and it's crucial for life.

15 Oct 2025

Researchers Develop New Technique to Detect Causality in Neural Spike Trains

Understanding the brain's functional architecture is a fundamental challenge in neuroscience. The connections between neurons ultimately dictate how information is processed, transmitted, stored, and retrieved, thus forming the basis of our cognitive functions.

10 Sep 2025

PV Interneurons Regulate Social Behavior and Empathy in Mice

A special set of neurons directs mice's attention to or away from their peers, depending on the situation. The Kobe University discovery has implications for finding causes for neuropsychiatric conditions such as autism spectrum disorder or schizophrenia.

27 Aug 2025

New Research Explains How Alcohol Inhibits Gut Health

Alcohol-associated liver disease (ALD) is a leading cause of liver transplantation and mortality globally, and its effect is only increasing.

27 Aug 2025

Hormone-Sensitive Brain Circuit Drives Mating Behaviors in Mice

In animals with social structures, the drive to reproduce is a complex process; governed by the brain, it's influenced by both internal cues such as hormones and external factors such as interactions with potential mates.

17 Jul 2025

Hippocampal Neurons Show Surprising Flexibility in Brain Signal Processing

The brain is constantly mapping the external world like a GPS, even when we don't know about it. This activity comes in the form of tiny electrical signals sents between neurons -- specialized cells that communicate with one another to help us think, move, remember and feel.

17 Jun 2025

UC Davis Study Links Specific microRNAs to Mental and Neurological Disorders

A study in Nature Aging from researchers at the UC Davis School of Medicine has identified specific microRNAs - non-coding RNAs that regulate gene expression within cells - that likely contribute to bipolar disorder, depression, schizophrenia, post-traumatic stress disorder (PTSD) and Parkinson's disease.

5 Jun 2025

Exon-Specific Analysis Uncovers Novel Insights into Psychiatric Disease

This research highlights the role of exons in mental illnesses, offering new perspectives on genetic factors that influence psychiatric disorder development.

3 Jun 2025