Tumor News and Research

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Light-Controlled Phagobots Offer Precision Immune Modulation

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells.

2 Jun 2025

Three-Dimensionally Reconstructed Kidney Glomerulus Simulates Structural and Functional Characteristics In Vitro

A 3D engineered kidney glomerulus model replicates structural and mechanical features of the glomerular filtration barrier, enabling the study of podocyte-related diseases and drug screening with improved physiological relevance.

2 Jun 2025

Study Identifies SMARCB1 and MEOX2 Genes as Growth Regulators of Lung Cancers

A Cancer Gene Therapy study reveals that MEOX2 promotes lung cancer progression while SMARCB1 acts as a tumor suppressor, influencing EGFR expression and response to tyrosine kinase inhibitors.

30 May 2025

Machine Learning Reveals Molecular Profile Differences in Colorectal Cancer Patients

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

24 May 2025

New Genomic Score Predicts Risk of Progression in Multiple Myeloma

A new risk assessment score developed by researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard reveals how multiple myeloma, a form of blood cancer, begins and progresses from precancerous to malignant states by tracing DNA mutations.

24 May 2025

Ultra-Rapid Genetic Test Revolutionizes Brain Tumor Diagnosis

Scientists and medics have developed an ultra-rapid method of genetically diagnosing brain tumors that will cut the time it takes to classify them from 6-8 weeks, to as little as two hours – which could improve care for thousands of patients each year in the UK.

21 May 2025

Compression Drives Aggressive Behavior in Liver Cancer Cells

Yale researchers are providing new insights into how physical forces, such as cells being compressed in physically restrictive environments, play key roles in cancer progression.

21 May 2025

Autophagy: A Double-Edged Sword in Cancer and Protein Conformational Disorders

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its potential as a therapeutic target and the challenges of tipping the balance between protection and harm.

20 May 2025

Protein Balance Offers Key to Overcoming Immunotherapy Resistance

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint inhibitors are one class of immunotherapy that block specific proteins from slowing the immune response.

15 May 2025

Loss of SOX9 Gene Linked to Aggressive Colorectal Cancer

Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes associated with colorectal cancer are known, how they contribute to cancer development is not yet well defined.

15 May 2025

How RNA-Binding Proteins and Circular RNAs Shape Tumor Biology

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

13 May 2025

Potential Therapeutic Target for Aggressive Colorectal Cancers

Colorectal cancer ranks as the second leading cause of cancer-related mortality worldwide.

13 May 2025

Novel Molecule Inducing Ferroptosis for Metastatic Cancer Therapy

Scientists from Institut Curie, the CNRS, and Inserm have just created a novel class of molecules capable of destroying cancer cells that are resistant to current treatments and cause recurrence.

8 May 2025

Reciprocal Regulatory Link Between ecDNA Maintenance and DNA Damage Response Revealed

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes.

29 Apr 2025

Johns Hopkins Team Identifies Distinct Subtypes of Senescent Skin Cells

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.

29 Apr 2025

New Drug Combo Shows Promise Against Aggressive Leukemia in Landmark Study

A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell differentiation and reducing tumor growth.

28 Apr 2025

Unraveling the Role of Long Noncoding RNAs in the Tumor Microenvironment

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to influence tumorigenesis, progression, and metastasis.

25 Apr 2025