Cell Biology

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Nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases

Researchers from the Institut national de la recherche scientifique (INRS) have shown that nanoparticles could be used to deliver drugs to the brain to treat neurodegenerative diseases.

10 Nov 2020

Study shows how UCH37 enzyme regulates a cell’s waste management system

Researchers reported the discovery of a new enzyme, called UCH37, that controls the waste management system of a cell.

9 Nov 2020

Environmental risk factors are important determinants of cardiovascular disease

In a current opinion article "Reduction of environmental pollutants for prevention of cardiovascular disease: it's time to act", published in the European Heart Journal this week.

9 Nov 2020

Glass surface embedded with self-assembled gold nanoparticles can improve live-cell imaging

In the quest to image exceedingly small structures and phenomenon with higher precision, scientists have been pushing the limits of optical microscope resolution, but these advances often come with increased complication and cost.

9 Nov 2020

White blood cells can be trained to attack tumor cells

Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program - be utilized for the treatment of tumors.

9 Nov 2020

New method to improve preclinical evaluation of CAR-T cell therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies.

9 Nov 2020

Researchers show how encapsulated viruses hijack biosynthetic pathways in cells

Researchers from the Universities of Melbourne, York, Warwick and Oxford have shed light on how encapsulated viruses like hepatitis B, dengue and SARS-CoV-2 hijack the protein manufacturing and distribution pathways in the cell - they have also identified a potential broad spectrum anti-viral drug target to stop them in their tracks.

9 Nov 2020

Ground-breaking discovery provides new understanding of how proteins operate

A ground-breaking discovery by Centenary Institute scientists has provided new understanding as to the nature of proteins and how they exist and operate in the human body.

9 Nov 2020

Unrelated mutations can lead to false positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

6 Nov 2020

Study shows how coronavirus block cells’ ability to produce protective proteins

One of the novel coronavirus' most insidious tricks is that it can block the ability of cells to produce protective proteins without hindering its own ability to replicate.

6 Nov 2020

Experts use super-resolution microscopy to observe individual synapse proteins

In the synapses of nerve cells (neurons), there are hundreds of specialized proteins that are important for the functioning of the nervous system. If something goes wrong here, neurological or psychiatric diseases can be the result - Alzheimer's and Parkinson's, depression, and schizophrenia are just a few of them.

6 Nov 2020

LipiDiDiet project shows positive effects of nutrient intervention in early Alzheimer’s disease

Trial participants who received a multinutrient formulation over an extended period of time showed a significantly less rapid deterioration in cognitive performance than the patients in a control group, who received only a placebo.

6 Nov 2020

Researchers outline the future effects of global warming on major cancers

Climate change will bring an acute toll worldwide, with rising temperatures, wildfires and poor air quality, accompanied by higher rates of cancer, especially lung, skin and gastrointestinal cancers, according to a new report from UC San Francisco.

6 Nov 2020

Researchers reveal identity of the last unknown protein of autophagy

Drs. Nobuo Noda (Director) and Kazuaki Matoba (Senior Researcher) et al. at the Institute of Microbial Chemistry (BIKAKEN, Tokyo, Japan) discovered that Atg9, one of the proteins that function to mediate autophagy, has phospholipid-translocation activity (the lipid scramblase activity) between the two layers of the lipid bilayer and elucidated that the protein's activity brings about autophagosome membrane expansion.

5 Nov 2020

Teratomas could provide a new glance at human development

Finding just the right model to study human development--from the early embryonic stage onward--has been a challenge for scientists over the last decade.

From UC San Diego 5 Nov 2020

Researchers identify a new solution for treating ligament injuries

Ligament injuries that affect scores of regular citizens and athletes are sidelined every year. Added to this, recovery is painful and takes a long time and, at times, a return to normal function is never achieved because of the formation of scars—an aspect that makes ligament injuries inclined to more damage.

4 Nov 2020