Cell Biology

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Researchers use AI to identify genes that are critical to a cancer cell’s survival

Researchers at the University of Sussex are using Artificial Intelligence (AI) technology to analyze different types of cancer cells to understand different gene dependencies, and to identify genes that are critical to a cell's survival.

6 Feb 2023

CAR T-cell therapy effective in mice with ovarian cancer

CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer.

6 Feb 2023

Study sheds light on why lung tumors do not respond well to immunotherapy

Immunotherapy -; drug treatment that stimulates the immune system to attack tumors -; works well against some types of cancer, but it has shown mixed success against lung cancer.

6 Feb 2023

Groundbreaking discovery could lead to new ways of controlling gene regulation

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

6 Feb 2023

Employing molecular anchor for more effective CAR immunotherapies

Researchers at St. Jude Children’s Research Hospital discovered that immune cells with the attached protein boosted the killing of cancer, irrespective of the kind of cancer cell or the type of cancer being targeted.

3 Feb 2023

Scientists unravel the physics of a cellular process linked to aggregation diseases

Researchers from Princeton University have uncovered the physics of a cellular process linked to aggregation diseases including Huntington's disease, paving the way to a deeper understanding of neurodegenerative disorders at the molecular level.

3 Feb 2023

Researchers establish and characterize a stable iPSC line for modeling human disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

RNA-G quadruplexes in living cells: A real-time study

Amyotrophic lateral sclerosis (ALS), sometimes referred to as Stephen Hawking’s disease and Lou Gehrig’s disease is a neurological condition that causes the body’s muscles to gradually lose control.

2 Feb 2023

Cancer therapies improved by changing an antibody’s binding to a target

Before World Cancer Day (4th February), new research from the Centre for Cancer Immunology at the University of Southampton has demonstrated that altering how firmly an antibody attaches to a target can enhance cancer treatments.

2 Feb 2023

Scientists define four cancer molecular subtypes using PDX models

Metastasis, the process by which cancer cells leave the primary tumor and spread to other tissues to seed new cancerous growth, causes most cancer deaths.

2 Feb 2023

Deletion of p16Ink4a cells does not negatively impact β-cell mass and proliferation in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, entitled, "Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity."

1 Feb 2023

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Research findings published in Frontiers in Immunology show that cancer immunotherapy does not interfere with COVID-19 immunity in previously vaccinated patients.

1 Feb 2023

Cochlear organoids provide a platform to understand sensorineural hearing loss

Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.

1 Feb 2023

Study findings may pave way for personalized cancer treatment

In a step likely to advance personalized cancer treatment, scientists have for the first time shown in patients that levels of biomarkers are not enough to tell which patients are likely to respond best to immunotherapy.

31 Jan 2023

CHOP scientists build a custom tool that drastically reduces engraftment reporting error rates

Researchers at Children's Hospital of Philadelphiahave developed a custom-built application to automate determination of engraftment, a key outcome after hematopoietic stem cell transplant (HSCT).

31 Jan 2023

Effective new drugs to reduce the massive number of malaria cases

Malaria is known as a disastrous disease, with 247 million cases and 619,000 deaths reported in 2021 alone.

From The University of New South Wales (UNSW) 31 Jan 2023

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two hallmarks of quality

The Stem Cell and Bone Marrow Transplant Program at Cedars-Sinai Cancer was recently recognized with two important hallmarks of quality: official accreditation for CAR T-cell therapy, and a third year in a row ranking among the top adult bone marrow transplant programs in the U.S.

31 Jan 2023

Cell Biology

Researchers use AI to identify genes that are critical to a cancer cell’s survival

CAR T-cell therapy effective in mice with ovarian cancer

Study sheds light on why lung tumors do not respond well to immunotherapy

Groundbreaking discovery could lead to new ways of controlling gene regulation

Employing molecular anchor for more effective CAR immunotherapies

Scientists unravel the physics of a cellular process linked to aggregation diseases

Researchers establish and characterize a stable iPSC line for modeling human disease

RNA-G quadruplexes in living cells: A real-time study

Cancer therapies improved by changing an antibody’s binding to a target

Scientists define four cancer molecular subtypes using PDX models

Deletion of p16Ink4a cells does not negatively impact β-cell mass and proliferation in mice

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Cochlear organoids provide a platform to understand sensorineural hearing loss

Study findings may pave way for personalized cancer treatment

CHOP scientists build a custom tool that drastically reduces engraftment reporting error rates

Effective new drugs to reduce the massive number of malaria cases

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two hallmarks of quality

Massive clinical study on type 1 diabetes patients

Novel protein degradation technology provides functional insights into how CTCF regulates transcription

Accumulation of collagen at injured sites in the gut stimulates cellular reprogramming, study reveals

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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