Drug Discovery & Pharmaceuticals

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Study shows how individualization with pharmacogenomics could impact COVID-19 treatments

Over the past few months, a number of drugs have been under investigation to treat COVID-19 without well-established safety or data to support these claims.

28 Aug 2020

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

New syringe technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

25 Aug 2020

Researchers describe new approach involving "antivitamins" to develop new antibiotics

Antibiotics are among the most important discoveries of modern medicine and have saved millions of lives since the discovery of penicillin almost 100 years ago.

25 Aug 2020

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Given the global urgency of the COVID-19 pandemic, Microsoft's AI for Health program has stepped in to support the development and potential deployment of Vaxine's COVAX-19™ vaccine with a philanthropic grant.

25 Aug 2020

Researchers find associations of lifelong antimicrobial drug use with saliva microbiota diversity

The human microbiota plays an important role in health and well-being by assisting in digestion, producing nutrients, resisting invading pathogens and regulating metabolism and the immune system.

25 Aug 2020

Researchers add a component to make cancer vaccine more effective

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

25 Aug 2020

New study shows promise for developing COVID-19 vaccine

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

24 Aug 2020

Cashew shell compound shows therapeutic potential for demyelinating diseases

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reports today in the Proceedings of the National Academy of Sciences.

From Vanderbilt University 19 Aug 2020

Drugs designed to lower alpha-ketoglutarate levels could help fight DIPG tumors

Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures.

19 Aug 2020

RNA-based therapeutic approach could be used to cure hereditary diseases

Short RNA molecules can be used as medication. Their effectiveness is based on the genetic information they carry: therapeutic RNA can bind to the body's own RNA and thus influence how it functions.

19 Aug 2020

New technique could accelerate drug research for various diseases

Alicyclic compounds are groups of organic chemical compounds that have led to the development of a number of medications.

19 Aug 2020

Novel receptor protein can be a promising treatment for COVID-19

A novel receptor protein that binds to the SARS-CoV-2 virus and prevents it from entering cells may hold promise for treating COVID-19 and other coronavirus-related diseases, according to research published online Aug. 4 in the journal SCIENCE.

18 Aug 2020

Sustainable biotechnological production of coral antibiotic

Thomas Brück saw the sea whip Antillogorgia elisabethae for the first time 17 years ago while diving on a research trip to the Bahamas.

18 Aug 2020

Novel molecule shown to have potential therapeutic effects for arthritis

Arthritis affects almost 2% of the world's population, or some 150 million people, and currently, there is no completely effective treatment for this chronic disease. A new molecule developed in the laboratory has been shown to have potential therapeutic effects.

12 Aug 2020

Researchers use genome editing to facilitate drug discovery based on natural fungus

Rice University scientists have won federal support for their pursuit of novel drugs to treat human disease.

11 Aug 2020

Researchers are developing therapeutic treatments for acute stroke

Every year in the United States, about 800,000 people experience a stroke. Many are left with neurological complications such as paralysis on one side of the body, speech and language problems, vision issues, behavioral changes, and memory loss.

10 Aug 2020

Test pinpoints which people with gonorrhea can be treated with ciprofloxacin

A test designed by UCLA researchers can pinpoint which people with gonorrhea will respond successfully to the inexpensive oral antibiotic ciprofloxacin, which had previously been sidelined over concerns the bacterium that causes the infection was becoming resistant to it.

10 Aug 2020

Researchers are testing new way to deliver vaccines through microneedle skin patches

A revolutionary new way to give vaccines through microneedle skin patches is being tested at Swansea University, thanks to £200,000 of EU funding announced by the Welsh Government.

10 Aug 2020

Researchers find new way to create natural compound that shows promise as anti-cancer agent

Scripps Research chemists Hans Renata, PhD, and Alexander Adibekian, PhD, have discovered a way to efficiently create a synthetic version of a valuable natural compound called cepafungin I, which has shown promise as an anti-cancer agent.

7 Aug 2020

Drug Discovery & Pharmaceuticals

Study shows how individualization with pharmacogenomics could impact COVID-19 treatments

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

New syringe technology for subcutaneous injection of viscous formulations

Researchers describe new approach involving "antivitamins" to develop new antibiotics

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Researchers find associations of lifelong antimicrobial drug use with saliva microbiota diversity

Researchers add a component to make cancer vaccine more effective

New study shows promise for developing COVID-19 vaccine

Cashew shell compound shows therapeutic potential for demyelinating diseases

Drugs designed to lower alpha-ketoglutarate levels could help fight DIPG tumors

RNA-based therapeutic approach could be used to cure hereditary diseases

New technique could accelerate drug research for various diseases

Novel receptor protein can be a promising treatment for COVID-19

Sustainable biotechnological production of coral antibiotic

Novel molecule shown to have potential therapeutic effects for arthritis

Researchers use genome editing to facilitate drug discovery based on natural fungus

Researchers are developing therapeutic treatments for acute stroke

Test pinpoints which people with gonorrhea can be treated with ciprofloxacin

Researchers are testing new way to deliver vaccines through microneedle skin patches

Researchers find new way to create natural compound that shows promise as anti-cancer agent

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