Drug Discovery & Pharmaceuticals

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MD Anderson and Virogin Biotech collaborate to advance the development of investigational oncolytic viruses, treatments

The University of Texas MD Anderson Cancer Center and Virogin Biotech today announced a strategic collaboration to accelerate the development of investigational treatments, including oncolytic viruses and immunotherapies, for patients with advanced cancers.

12 Sep 2022

Yeast platform for the production of plant-derived anti-cancer drug

The supply of a plant-derived anti-cancer drug can finally meet global demand after a team of scientists from Denmark and the U.S. engineered yeast to produce the precursor molecules, which could previously only be obtained in trace concentrations in the native plant.

1 Sep 2022

Therapeutic mRNAs do not significantly impact translational fidelity

Synthetic mRNA therapeutics for the treatment and prevention of disease has attracted a lot of interest due to the exceptional efficacy of mRNA vaccinations against SARS-CoV-2.

30 Aug 2022

Mayo Clinic's strategic collaboration in biomanufacturing focuses on delivering novel biotherapeutics

Mayo Clinic today announced a strategic collaboration in biomanufacturing to deliver novel biotherapeutics for rare and complex conditions.

17 Aug 2022

Extract from the roots of Rhodiola rosea may be effective for managing type 2 diabetes

A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

16 Aug 2022

New technique enables researchers to pinpoint protein–drug interaction

The discovery and development of new drugs may be facilitated by the use of a novel method that can analyze the interactions of drug molecules with proteins in tissue samples. In cooperation with the major biopharmaceutical company AstraZeneca, University of Birmingham researchers created the method.

15 Jul 2022

Challenges in Drug Discovery; Where are we now, and where are we going?

As part of our SLAS Europe 2022 coverage, we speak to Steve Rees, Vice-President of Discovery Biology at AstraZeneca, about the challenges currently faced by the drug discovery sector.

From Society for Laboratory Automation and Screening (SLAS) 8 Jul 2022

How can High-Content Screening accelerate Drug Discovery?

As part of our SLAS Europe 2022 coverage, we speak to Professor Jeremy Simpson from the University College Dublin about the role high-content screening can play in accelerating drug discovery.

From Society for Laboratory Automation and Screening (SLAS) 6 Jul 2022

New biomedical research tool may help advance molecular diagnostics and drug discovery

A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery.

30 Jun 2022

Sharks may be key to developing effective COVID-19 treatments

To combat viruses, one of humankind's oldest threats, researchers are studying predators with the oldest adaptive immune system in the animal kingdom: sharks.

1 Jun 2022

Research shows how current drugs impact bacterial physiology

Tuberculosis is a stubborn disease caused by even more stubborn bacteria. While many bacterial infections clear up within days of taking antibiotics, TB can take up to six months to clear up and, in some cases, never leave the human body. In 2020, it claimed 1.5 million lives, second only to COVID-19 in terms of infectious disease deaths.

1 Jun 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

27 May 2022

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical that had shown promise in initial studies for treating cancer.

24 May 2022

New open-source tool automates RNA analysis, likely to encourage research and drug development

Scripps Research scientists have introduced a new software tool for examining RNA (ribonucleic acid) molecules, which play a variety of important roles in living things.

10 May 2022

Radioconjugate drugs could change the future of cancer treatment

Many current cancer treatments make patients very sick because even the most targeted treatments kill healthy cells as well as cancer cells. But a new type of treatment called a radioconjugate is getting the attention of oncologists.

21 Apr 2022

Scientists discover an effective drug development candidate from rare actinomycetes

Researchers are rushing to review a group of bacteria known as actinomycetes, which are one of the most successful sources of treatment.

19 Apr 2022

Study shows how peptide inhibitor helps to treat Alzheimer’s and Huntington’s disease

According to the Alzheimer’s Association, around 11% of the population, comprising 65-year old and above—in the United States has been diagnosed with Alzheimer’s disease (AD), the most prevalent form of dementia that causes memory loss and cognitive impairment.