Drug Discovery & Pharmaceuticals

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New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

3 Aug 2023

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

The University of Texas MD Anderson Cancer Center and Nexo Therapeutics today announced a multi-year strategic collaboration that aligns the innovative technology and capabilities of each organization at the earliest stages of drug discovery and development to rapidly advance impactful new cancer therapies against previously undruggable targets.

26 Jul 2023

Analyzing the Possibility to Design Improved Vaccines

A new paper in Biology Methods & Protocols, published by Oxford University Press, shows it may be possible to design vaccines that will induce a stronger immune response to infecting pathogens, such as the virus causing COVID-19.

26 Jul 2023

Researchers Design New Algorithm to Boost Pandemic Preparedness

Immune system researchers have designed a computational tool to boost pandemic preparedness. Scientists can use this new algorithm to compare data from vastly different experiments and better predict how individuals may respond to disease.

26 Jul 2023

Researchers Make Breakthrough in Fight Against Familial Hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world.

21 Jul 2023

New Vaccine Shows Promise in Combating MenB

Investigators from the Universities of Surrey and Oxford have declared that a vaccine candidate that can shield children from Meningococcal group B (MenB), which can cause meningitis, has advanced to clinical development.

19 Jul 2023

Government Backing UK Engineering Biology Firms to Revolutionise Medicine, Food and Environmental Protection

The UK firms harnessing the power of biology to deliver new medical therapies, means of recycling and environmentally-friendly food sources will be under the spotlight at Downing Street today (Wednesday 19 July) as science leaders and Ministers meet to unleash the full potential of the UK’s engineering biology sector.

19 Jul 2023

Berkeley Lab and Genentech Team Up to Develop Next-Generation Drug Delivery System

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

18 Jul 2023

New P38 Inhibitors Selectively Target Cardiac Cell Death

The p38 protein regulates a wide variety of cellular functions and is related to diseases such as chronic inflammation, immunological disorders, or cancer.

14 Jul 2023

AI-Powered Collaboration Aims to Transform Drug Development

Critical Path Institute (C-Path), a leading global nonprofit committed to expediting drug development through the acceleration of regulatory-endorsed solutions, today announced a newly formalized Memorandum of Understanding (MOU) with Vivpro, an industry-leading provider of a revolutionary biointelligence software platform and innovative services.

14 Jul 2023

Study Provides More Treatment Options for Severe COVID-19

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis.

11 Jul 2023

'Purecap' Technique Produces Highly Active mRNA Vaccines with Lower Immunostimulatory Activity

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

6 Jul 2023

TTUHSC and TTU Researchers Uncover Promising Leads in the Fight Against Leishmaniasis

Leishmaniasis is a tropical disease caused by parasites known as Leishmania, which are transmitted to humans and animals through the bites of more than 90 species of sand flies.

23 Jun 2023

Rescue Treatment Found From Plant Extracts for People With Ataxia

A University of California, Irvine-led team of researchers have discovered that extracts from plants used by the Kwakwaka'wakw First Nations peoples in their traditional botanical medicine practices are able to rescue the function of ion channel proteins carrying mutations that cause human Episodic Ataxia.

22 Jun 2023

Metrion Biosciences Appoints Dr Steve Jenkinson as VP, Drug Discovery and Safety Assessment to Strengthen US Operations

Metrion Biosciences Ltd (“Metrion”), the specialist ion channel contract research and drug discovery company, today announced the appointment of Dr Steve Jenkinson as Vice President, Drug Discovery and Safety Assessment.

12 Jun 2023

Researchers Discover Novel Combination Therapy to Counter Antibiotic-resistant Mycobacterium Abscessus Infections

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Nanyang Technological University Singapore (NTU Singapore) and National University Hospital (NUH), have discovered a novel therapy by combining two antibiotics, rifaximin and clarithromycin, to treat Mycobacterium abscessus (M. abscessus), a non-tuberculous mycobacterium (NTM) that causes chronic lung-related infections.

9 Jun 2023

Natural Peptide From Fruit Flies may Pave Way for New Antibiotics

Scientists at the University of Illinois Chicago have found that a peptide from fruit flies could lead to new antibiotics.

7 Jun 2023

Breakthrough: Sequencing Functional Antibody Proteins Directly from Human Blood

Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the serum of a human patient after receiving a COVID-19 vaccine.

6 Jun 2023

Using Synthetic Peptides in Next-Generation Inflammatory Disease Diagnostic Assays

Conditions like ulcerative colitis and Crohn's disease, which cause inflammation in the body, can be identified or tracked by measuring a protein called calprotectin.

29 May 2023

Failed Antibiotics Could Become Weed Killers in the Future

Weed killers of the future could soon be based on failed antibiotics.

25 May 2023

Drug Discovery & Pharmaceuticals

New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

Analyzing the Possibility to Design Improved Vaccines

Researchers Design New Algorithm to Boost Pandemic Preparedness

Researchers Make Breakthrough in Fight Against Familial Hypercholesterolemia

New Vaccine Shows Promise in Combating MenB

Government Backing UK Engineering Biology Firms to Revolutionise Medicine, Food and Environmental Protection

Berkeley Lab and Genentech Team Up to Develop Next-Generation Drug Delivery System

New P38 Inhibitors Selectively Target Cardiac Cell Death

AI-Powered Collaboration Aims to Transform Drug Development

Study Provides More Treatment Options for Severe COVID-19

'Purecap' Technique Produces Highly Active mRNA Vaccines with Lower Immunostimulatory Activity

TTUHSC and TTU Researchers Uncover Promising Leads in the Fight Against Leishmaniasis

Rescue Treatment Found From Plant Extracts for People With Ataxia

Metrion Biosciences Appoints Dr Steve Jenkinson as VP, Drug Discovery and Safety Assessment to Strengthen US Operations

Researchers Discover Novel Combination Therapy to Counter Antibiotic-resistant Mycobacterium Abscessus Infections

Natural Peptide From Fruit Flies may Pave Way for New Antibiotics

Breakthrough: Sequencing Functional Antibody Proteins Directly from Human Blood

Using Synthetic Peptides in Next-Generation Inflammatory Disease Diagnostic Assays

Failed Antibiotics Could Become Weed Killers in the Future

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

Latest in Genomics