Genomics

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Mapping Thousands of Conserved Gene Groups Across Grasses

A new computational biology pipeline has mapped out over 13,000 groups of protein-coding genes conserved across grasses, offering a powerful tool for researchers investigating gene function in these economically and ecologically vital species.

2 Jul 2025

New Clues Reveal How Multicellularity Evolved in Early Animals

Animals, from worms and sponges to jellyfish and whales, contain anywhere from a few thousand to tens of trillions of nearly genetically identical cells.

2 Jul 2025

New Chordata Olfactory Receptor Database Offers Insight into the Genetics of Scent

Olfactory receptors (ORs) are key to how animals perceive their surroundings, guiding behaviors like foraging, mating, and avoiding danger.

1 Jul 2025

Genetic Ancestry Tied to Immune Response in Dengue Infection

For the first time, the extreme variability in dengue fever has been linked to a biological mechanism, potentially opening doors to new treatments and vaccines for the most common mosquito-borne disease worldwide.

1 Jul 2025

New Tool Reveals RNA Locations Inside Cells With Nanoscale Precision

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells – providing valuable clues to where different RNA species are distributed spatially in response to various cellular cues.

30 Jun 2025

Chromosome Imbalance Disrupts Mitochondria Through Protein Aggregates

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances.

30 Jun 2025

Reactivating a Genetic Switch Restores Ear Regeneration in Mice

By flipping an evolutionarily disabled genetic switch involved in Vitamin A metabolism, researchers have enabled ear tissue regeneration in mice. Unlike some animals such as fish and salamanders, mammals have limited capacity to regenerate damaged tissues or organs fully.

27 Jun 2025

Worm Species Reveal Deep Genetic Similarities Across Evolutionary Time

Two species of worms, separated by 20 million years of evolution, have been found to activate their genes in nearly identical ways as they develop from a single cell to a fully formed organism.

27 Jun 2025

Tracing the Genetic Mosaic of India Through Ancient Ancestry and Modern Genomes

India's population is genetically one of the most diverse in the world, yet it remains underrepresented in global datasets.

27 Jun 2025

RNases Play Pivotal Role in Shaping the Molecular Foundation of Mendelian Disorders

A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.

26 Jun 2025

Parse Biosciences GigaLab to Support Mount Sinai Researchers in Generating One of the Largest Alzheimer's and Parkinson's Single Cell Datasets

Parse Biosciences today announced their commitment to support researchers from the Icahn School of Medicine at Mount Sinai in generating one of the largest single cell datasets focused on understanding alternative splicing events in the cells of Alzheimer's and Parkinson's patients.

From Parse Biosciences 26 Jun 2025

Gene Editing Halts Symptoms of Rare Smooth Muscle Disease in Preclinical Study

Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed.

25 Jun 2025

Genetic Tool Successfully Repairs Mitochondrial Mutations in Human Cells

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor.

25 Jun 2025

Fusion Genes Emerge as Key Drivers in Cancer Development

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with altered functions, often driving tumor progression.

25 Jun 2025

Newly Evolved Genes Found to Influence Human Cell Division

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria.

24 Jun 2025

Mapping Life’s Origins with Billions of DNA Barcodes

A landmark study by WEHI scientists has shed new light on one of the most fundamental mysteries of biology: how cells divide and grow into the complex structures that make up our bodies.

24 Jun 2025

Advancing Gene Editing Through Values-Based Regulation

The review from the University of Adelaide argues for balanced regulations on gene editing to support innovation while ensuring societal safety and benefits.

24 Jun 2025

CRNKL1 Gene Identified as Key to Rare Neurological Disorder

A study identifies specific changes in the CRNKL1 gene, revealing its crucial role in brain development and the severe impacts of related genetic disorders.

24 Jun 2025

Imported Seafood and the Spread of Colistin Resistance

Findings show imported seafood as a potential source of colistin-resistance genes, underscoring the urgency of addressing antimicrobial resistance globally.

23 Jun 2025

UT Southwestern Researchers Develop Multi-Organ Gene Editing Strategy

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

23 Jun 2025