Genomics

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Researchers Discover Novel Clubroot Resistance Gene Crr5 in Chinese Cabbage

Clubroot disease, caused by Plasmodiophora brassicae, is a devastating soil-borne pathogen that severely threatens global production of cruciferous crops.

28 Oct 2025

Mutation in NAMPT Gene Found to Cause Rare Neurological Disease

An international research team, led by Shinghua Ding at the University of Missouri, has identified a previously unknown genetic disease that affects movement and muscle control.

28 Oct 2025

TRF1 Knockout Mice Exhibit Healthier Metabolic States Without Telomere Shortening

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

28 Oct 2025

Rhizosphere Metabolites Play Key Role in Regulating the Distribution of Antibiotic Resistance Genes

Their study reveals that rhizosphere metabolites-substances secreted by plant roots-play a crucial role in regulating the distribution of manure-derived ARGs in both the soil and plant tissues.

27 Oct 2025

First Chromosome-Scale Genome Assembly of Blackcurrant Reveals Drought Adaptation Strategies

Drought stress disrupts plant growth, metabolism, and reproduction, with devastating effects on crop productivity worldwide.

27 Oct 2025

Simple Genetic Switch can Underlie Temperature-Mediated Plasticity in Butterfly Wing Patterns

Scientists from the National University of Singapore (NUS) have discovered a simple DNA "switch" that helps tropical butterflies adjust the size of their wing eyespots in response to seasonal temperatures, shedding light on the evolution of environmental sensitivity.

27 Oct 2025

Study Reveals How TR4 Fungus Silences Banana Defense Genes

Bananas rank among the world's most valuable staple crops, yet their production faces severe losses from Fusarium wilt caused by Fusarium oxysporum f. sp. cubense (Foc) tropical race 4 (TR4).

24 Oct 2025

RNA-Based Molecular Switch Enhances Disease Resistance in Pears

In recent years, scientists have uncovered the remarkable regulatory power of long non-coding RNAs (lncRNAs) - RNA molecules once dismissed as "genetic dark matter."

24 Oct 2025

Disrupted Circadian Rhythms Alter Gene Activity in Alzheimer’s Disease

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

24 Oct 2025

Hidden RNA Inside a Gene Solves Decades-Old Telomere Mystery in Roundworms

An international research team led by Hiroki Shibuya at RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has solved a genetic mystery and revealed a previously unknown way that DNA can control what cells do.

24 Oct 2025

New Retron-Based Gene Editing Method Corrects Multiple Disease-Causing Mutations

Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person's genome, often with enough variation that even two individuals who share the same disorder might have a different combination of mutations.

24 Oct 2025

DNA Cassettes Enable Long-Lasting Antibody Production Directly Inside Patients

A multidisciplinary team of scientists led by The Wistar Institute, including Perelman School of Medicine at the University of Pennsylvania, AstraZeneca and Inovio Pharmaceuticals, published today in Nature Medicine a breakthrough in biologic antibody production that happens directly in human subjects in this encouraging first clinical trial of its kind.

23 Oct 2025

Research Pinpoints HMGN1 as Cause of Trisomy 21-Related Heart Abnormalities

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

23 Oct 2025

Biological Bulldozer Mechanism Explains Ants’ Powerful Sense of Smell

Ants have evolved an acute sense of smell, which requires each sensory neuron to choose one scent receptor out of hundreds.

23 Oct 2025

New Method Brings Precision to Monitoring Beneficial Bacteria After FMT

Researchers at the Icahn School of Medicine at Mount Sinai and their collaborators have developed a new technology to track beneficial bacteria after fecal microbiota transplants (FMT).

23 Oct 2025

Croatian Scientists Rewrite the Story of Cell Division

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in fact plays a completely different role in chromosome movement.

22 Oct 2025