Genomics

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Rice Researchers Create Accurate 3D Structures of Chromosomes Using FI-Chrom Method

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't used as often.

28 Jan 2026

New Epigenetic Catalog Helps Explain Individual Differences in Immune Responses

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection.

28 Jan 2026

Expanding CRISPR to Tackle Incurable Skin Diseases

Gene-editing techniques such as CRISPR have enabled new treatments for previously incurable diseases. Researchers at the University of British Columbia are now expanding those capabilities to include the skin for the first time.

28 Jan 2026

Melbourne Scientists Use AI to Tame CRISPR

Last year a ten-month old baby in the US was the first person in the world to have their rare genetic disease effectively cured through the use of CRISPR gene editing technology.

27 Jan 2026

Novel Epigenetic Regulator Enhances Downy Mildew Resistance in Brassica rapa

Downy mildew is a major constraint on Brassica crop production worldwide, especially during early developmental stages when plants are highly vulnerable to infection.

27 Jan 2026

Prehistoric Genome Pushes Back Origins of Treponemal Diseases in the Americas

Scientists have recovered a genome of Treponema pallidum – the bacterium whose subspecies today are responsible for four treponemal diseases, including syphilis – from 5,500-year-old human remains in Sabana de Bogotá, Colombia.

24 Jan 2026

Large African Ancestry Genetic Study Reveals Shared Biology Of Schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

24 Jan 2026

Maternal And Fetal Cell Exchange Shapes Health Across Multiple Generations

During pregnancy, maternal and fetal cells migrate back and forth across the placenta, with fetal cells entering the mother's bloodstream and tissues.

24 Jan 2026

Bioinformatic Framework Reconstructs Evolutionary History of Complex Polyploid Genomes

Whole-genome duplication has repeatedly reshaped plant genomes and driven evolutionary innovation, ecological adaptation, and crop diversification.

24 Jan 2026

Coordinated Gene Regulation Drives Saponin Production

Triterpenoid saponins are widely valued for their diverse pharmacological activities and also play important defensive roles in plants.

22 Jan 2026

Hidden Sperm RNA Remodeling With Age May Impact Next Generation

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown.

21 Jan 2026

Yeast-Based Platform Achieves Animal-Free High Quality Chondroitin Sulfate

By systematically redesigning multiple metabolic modules inside Komagataella phaffii, the researchers achieved both high product yield and high sulfation quality, two goals that have long been difficult to reach at the same time.

21 Jan 2026

Replacing Large Mouse Gene Regions with Human DNA

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.

19 Jan 2026

Fly Pigmentation Study Uncovers Genes Influencing Dopamine, Sleep, and Movement

Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to conditions like Parkinson's disease, depression and sleep disorders.

14 Jan 2026

Marsupial Gut Microbiomes Show Diet Adaptations, Antibiotic Resistance Risks

Marsupials are a group of mammals that encompass many of Australia's most iconic animals, unique because of their geographically isolated evolution.

14 Jan 2026

New Pangenomic Approach Enables Unprecedented Scaling for Genetic Data

Researchers at the University of California have created a novel data structure and compression method that allows pangenomics to process genetic information at previously unattainable scales.

14 Jan 2026

Giant Virus with A Massive Genome and Unusual Infection Strategy

Ushikuvirus, a newly identified giant virus, showcases unique cytopathic effects and structural features, enhancing knowledge of viral evolution and diversity.

14 Jan 2026

New Algorithms Automate Counting of Sister Chromatid Exchanges in Microscope Images

Researchers from Tokyo Metropolitan University have developed a suite of algorithms to automate the counting of sister chromatid exchanges (SCE) in chromosomes under the microscope. Conventional analysis requires trained personnel and time, with variability between different people.

12 Jan 2026

Giant Virus Uses Unique Codon Strategy to Optimize Host Resource Usage

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency partially depends on the usage of a codon, or sequence of three nucleotides, that matches the cellular pool of tRNA, key molecules in translation.

12 Jan 2026

Population-Specific Proteomic Analysis Advances Precision Medicine for Type 2 Diabetes

Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in individuals from continental Africa.

9 Jan 2026