Genomics

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Building a Large-Scale Atlas of Female Reproductive System Aging

Despite affecting half of the world's population, menopause has historically been understudied and misunderstood, both in biomedical research and clinical practice.

30 Apr 2026

Pronuclei Size Competition Maintains Gene Regulation in Early Embryos

The sperm and the egg cell's nuclei compete for size directly after fertilization and this is necessary for the proper embryonic development.

30 Apr 2026

AI Reveals Dynamic DNA Accessibility Within Nucleosome Structures

Every cell in the human body squeezes over six feet of DNA into a miniscule speck invisible to the naked eye-like compressing a whole house into a single sugar cube.

30 Apr 2026

Stage-Dependent Gene Expression Changes Reveal Cellular Aging Dynamics

A new research paper was published in Volume 18 of Aging-US on April 10, 2026, titled "Stage-dependent transcriptomic changes in human dermal fibroblast senescence model."

30 Apr 2026

Prime Assembly Approach Transforms Gene Therapy With Large DNA Inserts

New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment from cancellation of disease-causing mutations to replacement of an entire gene, scientists say.

30 Apr 2026

Long Read Sequencing Uncovers Telomere Length Variation Across Chromosomes

In a new proof-of-concept study published in Nature Communications, researchers at the University of Chicago analyzed genomic data from more than 2,500 participants in the national All of Us research program to estimate chromosome-specific telomere length (csTL).

30 Apr 2026

New Pipeline Sharpens Single-Cell Profiling of CAR Immune Therapies

CERTOMICS is a Nextflow-based computational pipeline designed to identify and profile CAR-engineered immune cells using single-cell multiomics data. By integrating gene expression, immune receptor profiling, protein markers, CAR-aware references, and CAR-specific quality control, it supports more standardized analysis of adoptive cellular immunotherapies.

29 Apr 2026

MD Anderson Researchers Map DNA Replication Stress at Single-Cell Resolution

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with single-cell resolution.

28 Apr 2026

Lund Researchers Map Epigenome Secrets of Insulin and Glucagon Cells

Researchers at Lund University in Sweden have carried out the most detailed mapping to date of the epigenome in the cells that regulate the body's blood sugar levels.

27 Apr 2026

Re-Engineering the Cellular Factory to Build a Better Delivery System for Gene Editors

Gene editing has emerged as a powerful approach for targeting the genetic causes of disease, but getting the editing machinery into the right cells efficiently, safely, and at the scale needed for therapies remains one of the biggest set of challenges in the field.

25 Apr 2026

Plant Peroxisome Study Offers New Insights Into Conserved Cellular Functions

For most of their lives, plants get their energy from photosynthesis. But during the seed to seedling stage when they can't absorb light just yet, they rely on other sources, like fatty acids.

25 Apr 2026

New Genetic Pathways Linked to Cardiometabolic Disease Identified

A study published today in PLOS Medicine has identified two new genetic pathways that contribute to cardiometabolic disease, which includes heart disease, obesity and diabetes.

24 Apr 2026

Ancient Genetic Sequences Found to Drive Human Language Abilities

In a first-of-its-kind finding, researchers at University of Iowa Health Care discovered that specific genetic sequences have an outsized impact on humans' language abilities and that these sequences evolved before humans and Neanderthals diverged.

23 Apr 2026

Genetic Study Reveals Biological Drivers of Frailty in Aging

Researchers at McMaster University have identified, for the first time, a novel region of DNA and two associated genes connected to frailty, offering neurological and immune-related insights that might help explain why some older adults are more likely to be frail than others.

22 Apr 2026

Scientists Map Human Genes That Control HIV Infection Dynamics

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body.

21 Apr 2026

Epigenetic Regulators Shape Gene Activity in Unexpected Ways

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off.

21 Apr 2026

Structured National Genomic Program can be Effective for Rare Disease Diagnosis

For many families, eight years of uncertainty meant repeated specialist visits, inconclusive genetic tests and the growing fear that a clear answer might never come. For nearly half of the children enrolled in the Telethon Undiagnosed Disease Program (TUDP), that wait is now over.

21 Apr 2026

Sylvester Cancer Center Launches Cloud-Based Platform for Unified Genomic Data

Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, has developed a novel, cloud-based informatics platform that combines clinical and genomic data from multiple sources into one unified platform.

21 Apr 2026

New Data Demonstrates the Unique Scalability of Evaxion’s AI-Immunology™ Platform in Glioblastoma

Evaxion A/S (“Evaxion”), a clinical-stage TechBio company developing novel vaccines with its pioneering AI-Immunology™ platform, announces new data demonstrating the platform’s ability to also potentially develop vaccines for glioblastoma (brain cancer).

From Evaxion A/S 21 Apr 2026

Regulatory Genetic Elements Coordinate Temporal Activity of Key Developmental Gene

In a new study published in Genes & Development, research led by Dr Lila Allou at the MRC Laboratory of Medical Sciences (LMS) in London and Professor Stefan Mundlos at the Max Planck Institute for Molecular Genetics and Charité in Berlin demonstrates how different regulatory genetic elements coordinate the temporal activity of a key developmental gene.

20 Apr 2026