Genomics

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Mitochondrial Supercomplex Protein COX7RP Extends Lifespan and Healthspan

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.

11 Dec 2025

Heterosis in Crops Explained Through Complex Gene Interaction Analysis

When two homozygous plant lines with different characteristics are crossed, the resulting offspring are often more robust and productive than their parents.

11 Dec 2025

How Complex Microbial Communities Drive the Evolution and Spread of Antimicrobial Resistance

A new scientific review has uncovered how complex microbial communities, including those in the human gut and the natural environment, act as powerful engines that drive the evolution and spread of antimicrobial resistance.

11 Dec 2025

AI-Driven Method Uncovers Hidden Cancer Drivers

University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel cancer progression, paving the way for earlier and more precise treatments.

11 Dec 2025

Computational Method can Detect How Genes Interact to Influence Complex Human Traits

A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible.

11 Dec 2025

Scientists Discover First Human DNA-Cutting Enzyme That Responds to Tension

An international research team at the University of Hong Kong has discovered a human protein known as ANKLE1, which is recognized as the first DNA-cutting enzyme (nuclease) in mammals that can detect and respond to physical tension in DNA.

10 Dec 2025

AI-Powered Analysis Reveals How Gene Duplication Drives Plant Development

As global temperatures rise, Cold Spring Harbor Laboratory (CSHL) scientists work to grow stronger, more resilient crops. Yet, this process is challenging.

9 Dec 2025

Syntax Bio Develops CRISPR Technology to Program Stem Cell Gene Activity

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company's CRISPR-based Cellgorithm™ technology, which lays the groundwork for programmable control of gene activity in human stem cells and offers an alternative to the slow, variable manual processes researchers use today.

8 Dec 2025

Spatial Touchstone Project Brings Standardization to Spatial Transcriptomics

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located.

8 Dec 2025

PLAMseq Revolutionizes Simultaneous Analysis of Genome Proteins and Their Locations

A team from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labelled affinity-purified mass spectrometry plus sequencing) that, for the first time, allows simultaneous analysis of chromatin-associated proteins and their location in the genome in a single experiment.

5 Dec 2025

Benchmarking DNA Language Models for Precision Genomics

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA foundation language models.

4 Dec 2025

Epigenetic Signatures Explain How Andean Highlanders Thrive in Low Oxygen

DNA sequencing technology makes it possible to explore the genome to learn how humans adapted to live in a wide range of environments.

4 Dec 2025

Study Uncovers Principles Guiding Replication Initiation Across the Human Genome

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, and genetic disorders.

4 Dec 2025

Study Reveals How Cells Compensate for Missing Chromosomes

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy.

4 Dec 2025

New Evidence Shows Complex Life Began Far Earlier Than Previously Believed

Complex life began to develop earlier, and over a longer span of time, than previously believed, a groundbreaking new study has revealed.

4 Dec 2025

Study Exposes Ancestry Biases in Current Gene Annotations

Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ancestry, according to a study published today in Nature Communications.

4 Dec 2025

Harnessing Triploid Loquat to Unlock Aneuploid Diversity for Advanced Breeding

Triploid plants are widely valued in horticulture for desirable traits such as seedlessness, yield improvement, and stress resilience.

2 Dec 2025

New Label-Free Breakthrough for Studying Bacterial Shape Diversity

Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean has remained a major challenge, especially for species that can't be grown in the lab.

2 Dec 2025

Unraveling How GFAP Mutations Disrupt Mitochondria in Alexander Disease

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare.

2 Dec 2025

Ambiguous Stop Codons Expand the Genetic Code in Archaea

The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in a gene codes for a unique amino acid that's added to a chain of amino acids to make a protein.

2 Dec 2025