Genomics

RSS

New Method Discovers Genetic Switches More Quickly

Researchers led by Dubravka Vučićević at the Max Delbrück Center have developed a new method for discovering how DNA controls genes. Published in “Cell Genomics,” their technique can reveal the genetic “switches” that regulate important genes more quickly than existing methods.

10 Sep 2025

Unraveling How Fly Embryos Solve the Fundamental Problem of "Tissue Tectonic Collision"

Combining classic comparative approaches, including collecting species from the wild, and cutting-edge light-induced gene manipulation technology, researchers from Japan and Germany have discovered how developing fly embryos solve the fundamental problem of "tissue tectonic collision" when the rapidly expanding head and torso tissues crash into each other.

10 Sep 2025

Tracing Origins of Wnt Signaling Through the Lipocone Superfamily

Researchers have described a large set of previously unrecognized enzymatic domains – named the Lipocone superfamily – and outlined their evolutionary pathway from bacterial defense molecules to key players in human development.

10 Sep 2025

spVelo: A New Method for Integrating Spatial and Temporal Data in RNA Velocity Analysis

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it will be and its function.

8 Sep 2025

New Research Highlights a More Efficient CAR T Treatment

This review article focuses on the transformative potential of in vivo CAR T cell treatment in overcoming the constraints of standard CAR T cell production.

8 Sep 2025

Blocking SUMO2 Protein may be a Winning Strategy Against Synovial Sarcoma

In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay.

8 Sep 2025

Discovery of De Novo Genes Sheds Light on Peach Evolution and Traits

The emergence of new genes is a central driver of evolutionary innovation. While mechanisms such as duplication and horizontal gene transfer have been widely studied, de novo gene birth represents a unique pathway where functional genes arise from noncoding DNA.

8 Sep 2025

New Computational Tool Tracks How Genetic Variants Affect mRNA Stability

A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas - if their cars don't break down on the way.

8 Sep 2025

Ancient Plant Protein Unlocks New Strategy for Engineering Disease-Resistant Crops

Researchers led by Ken Shirasu at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have identified an ancient protein that has the potential to help defend plants against tens of thousands of different bacteria and other pathogens.

5 Sep 2025

Earth BioGenome Project Aims to Build a Digital Library of All Life

From the mighty blue whale to the humble baker’s yeast, scientists have barely begun to understand the vast genetic diversity among lifeforms.

5 Sep 2025

CRISPRi Screening Reveals Genetic Insights into Cyanobacteria Acclimation

Cyanobacteria are the most abundant photosynthetic microorganisms on Earth. They live in nearly every habitat throughout the world, from permafrost to hot springs and from soils to oceans.

5 Sep 2025

Mechanical Forces Influence the Evolution of Innovations in Early Development

A small tissue fold present in fruit fly embryos buffers mechanical stresses and may have evolved in response to mechanical forces.

4 Sep 2025

Scientists Uncover Hidden Role of Cas9 in Building Bacterial Immune Memory

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could use to edit the DNA of living cells.

4 Sep 2025

Microbial Signatures Help Distinguish Colorectal Tumors from Other Cancers

Colorectal cancer is unique in having its own microbial 'fingerprint' – according to new research from the University of East Anglia.

4 Sep 2025

Ancient Microbial DNA Recovered from Million Year Old Mammoth Remains

An international team led by researchers at the Centre for Palaeogenetics, has uncovered microbial DNA preserved in woolly and steppe mammoth remains dating back more than one million years.

3 Sep 2025

Automated 3D Imaging Uncovers Genetic Markers for Sorghum Leaf Arrangement

By reconstructing 366 sorghum plants from calibrated images, the team showed that automated measurements achieved near-human repeatability and enabled genome-wide association studies (GWAS) to uncover genetic markers linked to leaf orientation.

3 Sep 2025

Genetic Discovery Reveals How Plants Respond to Blue Light and Cold

Plants may be stuck in one place, but the world around them is constantly changing. In order to grow and flower at the right time, plants must constantly collect information about their surroundings, measuring things like temperature, brightness, and length of day.

3 Sep 2025

Tackling KRAS Mutations Unlocks New Hope for Pancreatic Cancer Patients

Accounting for nearly 90% of all pancreatic cancers, pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of just 13%. Late-stage diagnosis, limited surgical options, and toxic chemotherapy regimens contribute to its poor outcomes.

2 Sep 2025

DNA-Wrapped Nanoparticles Enhance Efficiency of Gene Editing Tools

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine.

2 Sep 2025

Genetic Evidence Links Human Migration to Linguistic Exchange

Throughout human history, there have been many instances where two populations came into contact – especially in the past few thousand years because of large-scale migrations as a consequence of conquests, colonialization, and, more recently, globalization.

2 Sep 2025