Genomics

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Multiple Genetic Changes Play Key Role in the Development of Complex Disorders

The genetic roots of a disease or disorder do not always grow into clear cut, easily diagnosed clinical features.

8 Oct 2025

New Computer-Driven Strategy Reveals How Membrane Proteins Maintain Stability

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring cells stick together.

8 Oct 2025

Intergenerational Transmission of Exercise Benefits Mediated by Sperm MicroRNAs

n a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen, and Di-Jun Chen from Nanjing University, together with Tao Zhang from Nanjing Medical University, reported groundbreaking findings in their paper entitled "Paternal exercise confers endurance capacity to offspring through sperm microRNAs."

7 Oct 2025

New Genetic Map of Human Metabolism Reveals How Genes Influence Health and Disease

A recent study published in Nature Genetics developed the largest genetic map of human metabolism, giving new insights into the role of metabolites in health and disease and providing a framework for future research.

6 Oct 2025

New Technology can Map RNA-Protein Interactions Inside Human Cells

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells - an achievement that could offer new strategies for treating diseases ranging from cancer to Alzheimer's.

3 Oct 2025

How GBA Mutations Drive Cognitive Decline in Parkinson's Disease

Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain.

3 Oct 2025

New Synthetic Proteins Boost Efficiency of Genome Editing Tools

Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated new synthetic proteins that can edit the human genome more efficiently than proteins provided by nature.

3 Oct 2025

Molecular Innovation Behind the Origin of Type V CRISPR-Cas Systems

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage.

30 Sep 2025

New SCOPE Tool Transforms Discovery of Gene-Regulating Proteins

A new tool greatly improves scientists' ability to identify and study proteins that regulate gene activity in cells, according to research led by Weill Cornell Medicine investigators.

30 Sep 2025

Chromosome Zippers Rely on DNA Junctions to Safeguard Fertility

Every new life begins after a genetic shuffle. When organisms make eggs or sperm, maternal and paternal chromosomes pair up and swap pieces of DNA in a process called crossing over.

26 Sep 2025

Study Reveals How Lymphatic Cells Preserve Immune Memory

A study published today in Nature Communications describes how lymphatic endothelial cells assist in generating robust immune memory, offering new insights into how the immune system functions.

26 Sep 2025

How Chromosome Crossovers Safeguard Fertility and Genetic Health

When a woman becomes pregnant, the outcome of that pregnancy depends on many things - including a crucial event that happened while she was still growing inside her own mother's womb.

25 Sep 2025

Enhancing Genome Editing Through Systematic CAST Optimization

Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes.

25 Sep 2025

Honeybee Food-Sharing Genes Linked to Human Social Behavior

The study links genetic variation to honeybee sociability, revealing insights into food-sharing behavior and its evolutionary significance in social networks.

25 Sep 2025

Aurora A Enzyme Guides Proper Nuclear Formation in Dividing Cells

Every time a eukaryotic cell divides, it faces a monumental challenge: It must carefully duplicate and divide its genetic material (chromosomes) equally, and then rebuild the nuclear envelope around the separated halves.

24 Sep 2025

Gut Microbes Influence Human Genes and Health

The trillions of microbes that live in the human gut may play a bigger role in health than previously thought, according to a new research by the University of Hawaiʻi at Mānoa.

24 Sep 2025

Oligo-Barcodes Enable High-Resolution Chromosome Mapping in Tropical Fruits

Karyotype analysis plays a central role in cytogenetics, helping to reveal evolutionary processes and species relationships.

23 Sep 2025

Chromatin Accessibility Shapes Growth and Stress Response in Blue Mold

Blue mold, caused by Penicillium expansum, is one of the most destructive postharvest diseases, leading to economic losses across fruit supply chains.

23 Sep 2025

Deciphering the Genetic Logic of Terpene Diversity in Plants

Angiosperms, representing nearly 90% of all plant species, dominate terrestrial ecosystems thanks in part to their sophisticated chemical communication systems.

22 Sep 2025

SHAT2 Transcription Factor Influences Rice Seed Shattering and Grain Traits

In natural ecosystems, the timely abscission of seeds in wild plants is a crucial adaptive trait that contributes to reproductive success, population renewal, and colony expansion.

22 Sep 2025