Genomics

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Simple inexpensive test determines the genetic susceptibility to PML

Four genetic mutations have been linked to progressive multifocal leukoencephalopathy (PML), a rare but sometimes fatal brain infection that can be provoked by dozens of FDA-approved drugs.

16 Dec 2022

Researchers gain insights into how density may change gene expression in some insects

A grasshopper hatched in a crowded environment may look and behave differently than a grasshopper hatched in isolation -; even if they have the same genes.

14 Dec 2022

Using CRISPR technology to reduce the symptoms of Huntington’s disease

A neurological condition called Huntington's disease (HD) results in a progressive decline in movement, coordination, and mental ability. It is brought on by a mutation in the huntingtin, or HTT, gene.

From UC San Diego 14 Dec 2022

Molecular regulation underlying emergency hematopoiesis uncovered

If the body’s emergency hematopoiesis program activates, it signifies an alert state of the immune system and serves two functions: In comparison to “normal mode” hematopoiesis, the emergency program results in enhanced replacement of immune cells consumed during infections or inflammations.

12 Dec 2022

Predictive classifier identifies patients who can skip radiation therapy

According to the findings of a meta-analysis proposed at the San Antonio Breast Cancer Symposium held on December 6–10th, 2022, patients with invasive breast cancer who had low scores on an investigational gene molecular signature seemed to have similar rates of local recurrence regardless of whether they received adjuvant radiation therapy after breast-conserving surgery.

12 Dec 2022

Ancient environmental DNA used to map a two-million-year-old ecosystem

Around 2 million years ago climate in Greenland resembled that forecasted under future warming containing trees such as poplars and birch and animals like hare, lemmings, mastodons and reindeer.

9 Dec 2022

FSU study shows the transgenerational transmission of aspartame-induced anxiety in mice

Florida State University College of Medicine researchers have linked aspartame, an artificial sweetener found in nearly 5,000 diet foods and drinks, to anxiety-like behavior in mice.

9 Dec 2022

'Harmless' species of Listeria developing characteristics potentially harmful to humans

In the food processing industry, the deadly bacteria Listeria monocytogenes is monitored closely. Not only can the bacteria make people extremely ill, it is known to be developing resistance to various food safety measures across the world.

6 Dec 2022

High-dose green tea extract may create liver damage in people with certain genetic variations

Long-term use of high-dose green tea extract may provide some protection against cancer, cardiovascular disease, obesity and type 2 diabetes, but it also may create liver damage in a small minority of the population.

2 Dec 2022

The link between tandem repeats and development of Schizophrenia

Each human cell is distinct because it is written in the DNA language.

1 Dec 2022

Specific genetic variant resulting in the early onset of epilepsy identified

Children’s Hospital of Philadelphia (CHOP) researchers have identified a particular genetic variant in SCN1A, the most common genetic epilepsy, that contributes to an earlier start of epilepsy with clinical features different from other epilepsies.

1 Dec 2022

Research could advance our understanding of evolution and the origins of cell motility

The origin of all biological movements, including walking, swimming, or flying, can be traced back to cellular movements; however, little is known about how cell motility arose in evolution.

1 Dec 2022

Importance of localizing BRCA gene mutations for ovarian cancer treatment

Mutations in the BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 persons, respectively, elevate the risk of various malignancies such as ovarian, breast, pancreatic, and prostate cancer considerably.

30 Nov 2022

Study unravels a novel function of the gene scissors

Many years earlier, the CRISPR/Cas9 gene scissors have been making a sensation in science and medicine. This new tool of molecular biology consists of its origins in an ancient bacterial immune system.

28 Nov 2022

Gaining better insights into the origins of jaws by DNA sequence

At Uppsala University, a DNA sequence found in jawed vertebrates has been discovered and characterized by scientists. This includes sharks and humans, but it is absent in jawless vertebrates, like lampreys.

28 Nov 2022

Newly developed tool helps snip out faulty genes in a safe manner

Scientists from the Massachusetts Institute of Technology (MIT) have come up with a new tool that has the potential to detach faulty genes and exchange them with new ones in a highly safe and effective way.

From Massachusetts Institute of Technology (MIT) 25 Nov 2022

Resolving evolutionary origins of the platypus of fungi

A new study led by a research group from the University of Alberta has shown that nearly 600 apparently diverse fungi that never quite discovered a fit along the fungal family tree have been shown to have a general ancestor.

25 Nov 2022

Breakthrough on the way to new therapeutic strategies

As far as the field of cancer research is concerned, hollow spheres composed of MYC proteins sets the stage. Researchers from Würzburg have found them out and have reported this discovery in the Nature journal.

25 Nov 2022

Fastest-evolved regions of the human genome diverged rapidly after split from chimpanzee ancestor

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

RNA-targeting strategy to repair the genetic cause of ALS and dementia

Researchers at UF Scripps Biomedical Research have created a potential treatment for a major factor in the development of ALS and dementia that functions by removing disease-causing RNA segments.

24 Nov 2022

Genomics

Simple inexpensive test determines the genetic susceptibility to PML

Researchers gain insights into how density may change gene expression in some insects

Using CRISPR technology to reduce the symptoms of Huntington’s disease

Molecular regulation underlying emergency hematopoiesis uncovered

Predictive classifier identifies patients who can skip radiation therapy

Ancient environmental DNA used to map a two-million-year-old ecosystem

FSU study shows the transgenerational transmission of aspartame-induced anxiety in mice

'Harmless' species of Listeria developing characteristics potentially harmful to humans

High-dose green tea extract may create liver damage in people with certain genetic variations

The link between tandem repeats and development of Schizophrenia

Specific genetic variant resulting in the early onset of epilepsy identified

Research could advance our understanding of evolution and the origins of cell motility

Importance of localizing BRCA gene mutations for ovarian cancer treatment

Study unravels a novel function of the gene scissors

Gaining better insights into the origins of jaws by DNA sequence

Newly developed tool helps snip out faulty genes in a safe manner

Resolving evolutionary origins of the platypus of fungi

Breakthrough on the way to new therapeutic strategies

Fastest-evolved regions of the human genome diverged rapidly after split from chimpanzee ancestor

RNA-targeting strategy to repair the genetic cause of ALS and dementia

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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