Histology & Microscopy

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Gold nanoparticles put spotlight on small drug molecules in live cells

Successful drug development has a significant impact on people's quality of life worldwide. Being able to track how molecules get into target cells, and observing what they do when they are inside, is key to identifying the best candidates.

From Osaka University 19 Nov 2020

New study shows patients' own stem cells can be used to grow new bone

A new, groundbreaking study from the University of Bergen (UiB) shows that a patients' own stem cells can be used to grow new bone. This can potentially help millions of people who are partially edentulous and have insufficient bone for the placement of dental implants.

17 Nov 2020

Glass surface embedded with self-assembled gold nanoparticles can improve live-cell imaging

In the quest to image exceedingly small structures and phenomenon with higher precision, scientists have been pushing the limits of optical microscope resolution, but these advances often come with increased complication and cost.

9 Nov 2020

Experts use super-resolution microscopy to observe individual synapse proteins

In the synapses of nerve cells (neurons), there are hundreds of specialized proteins that are important for the functioning of the nervous system. If something goes wrong here, neurological or psychiatric diseases can be the result - Alzheimer's and Parkinson's, depression, and schizophrenia are just a few of them.

6 Nov 2020

Researchers reveal identity of the last unknown protein of autophagy

Drs. Nobuo Noda (Director) and Kazuaki Matoba (Senior Researcher) et al. at the Institute of Microbial Chemistry (BIKAKEN, Tokyo, Japan) discovered that Atg9, one of the proteins that function to mediate autophagy, has phospholipid-translocation activity (the lipid scramblase activity) between the two layers of the lipid bilayer and elucidated that the protein's activity brings about autophagosome membrane expansion.

5 Nov 2020

Scientists detect light-absorbing 'tarballs' in the Himalayan atmosphere

Some people refer to the Himalaya-Tibetan Plateau as the "third pole" because the region has the largest reserve of glacial snow and ice outside of the north and south poles.

5 Nov 2020

New research finds clues for disarming antibiotic-resistant bacteria

A virus can stop bacteria from sharing genes for antibiotic resistance among themselves, Texas A&M AgriLife researchers have discovered.

4 Nov 2020

Combination of microscopy and machine learning helps detect fossil pollen grains

Plant biology researchers at the University of Illinois and computer scientists at the University of California Irvine have developed a new method of fossil pollen identification through the combination of super-resolution microscopy and machine learning.

27 Oct 2020

Scientists design cost-effective portable analyzers

Despite their high accuracy, the majority of the existing instrumental laboratory methods are very laborious and insufficient in terms of quick analysis of the objects under study. A team of scientists of Samara Polytech design cost effective portable analyzers.

23 Oct 2020

New nanodevices reveal how intracellular matter rearranges itself over time

Researchers have achieved, for the first time, a look into the complex workings of a cell from within the cell.

From University of Bath 22 Oct 2020

Future ocean warming and acidification could cause physical changes in marine mussels

The increased temperature and acidification of our oceans over the next century have been argued to cause significant physical changes in an economically important marine species.

12 Oct 2020

Research finds air pollution particles in the placentas of women

Pollution particles, including metals, have been found in the placentas of fifteen women in London, according to research led by Queen Mary University of London.

24 Sep 2020

UB biophysicist receives $2 million NIH grant to explore protein-RNA droplets

Inside human cells, proteins and RNA can cluster together to form spherical droplets that play vital roles in cellular processes as well as in certain human diseases.

23 Sep 2020

Researchers discover a mechanism that leads to the growth of cell nuclei

By far the most important process in cell development is how cells divide and then enlarge in order to multiply. A research team headed by Freiburg medical scientist Prof. Dr. Robert Grosse has now discovered that bundled fibers of actin within a cell nucleus play an important part in how they enlarge after division.

23 Sep 2020

Computer-designed proteins protect lab-grown human cells from SARS-CoV-2

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19.

10 Sep 2020

Researchers demonstrate sub-nanometer scale spatial resolution in Raman spectroscopy imaging

Prof. DONG Zhenchao and Prof. HOU Jianguo from University of Science and Technology of China (USTC) of Chinese Academy of Sciences (CAS) improved the spatial resolution from 8 nm to ~8 Å of photoluminescence imaging. It realized sub-molecular resolution with single molecule photofluorescence imaging for the first time.

31 Aug 2020