Histology & Microscopy

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AI-based holographic microscope monitors microplanktons at the individual level

For the first time, scientists can now watch the lives of microplankton at the individual level utilizing holograms produced in digital microscopes and processed by artificial intelligence (AI).

3 Nov 2022

Combination of microscopy and DNA analysis yields new insights into polar cod’s diet

An essential component of the Arctic food chain is polar fish. Along with colleagues from KU Leuven and the Alfred Wegener Institute, Sarah Maes (KU Leuven) and Fokje Schaafsma (Wageningen Marine Research) examined the diet of polar cod from the Barents Sea.

1 Nov 2022

Native 3D structure of the ciliary base witnessed for the first time

Because flaws in the cilia transport system can result in, for example, blindness or cystic kidneys, findings reported in Science offer new understandings of the molecular basis for different diseases.

20 Sep 2022

A new holographic microscope developed to observe neural networks in brain

Scientists headed by Associate Director Wonshik Choi of the Center for Molecular Spectroscopy and Dynamics in the Institute for Basic Science, Professor Kim Moonseok of The Catholic University of Korea, and Professor Myunghwan Choi of Seoul National University designed a new kind of holographic microscope.

19 Sep 2022

Research shows how developing sea anemones essentially 'exercise' to build their morphology

As humans, we know that an active lifestyle gives us some control over our form. When we hit the pavement, track our steps, and head to the gym, we can maintain muscle development and reduce body fat.

19 Sep 2022

Researchers develop microscopes for identifying biological activities in detail

Consider a PhD candidate with a fluorescence microscope and a live bacterial sample. How might these resources be used in the most effective way to get specific observations of bacterial division from the sample?

9 Sep 2022

Detecting multiple food poisoning bacteria based on color differences in scattered light from metals

Osaka Metropolitan University scientists have developed a simple, rapid method to simultaneously identify multiple food poisoning bacteria, based on color differences in the scattered light by nanometer-scaled organic metal nanohybrid structures (NHs) that bind via antibodies to those bacteria.

30 Aug 2022

New CRISPR RNA-guided Caspases could lead to promising antiviral and tissue engineering tools

New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.

26 Aug 2022

Scientists create a miniaturized environment to unravel the secrets of plant health, carbon storage

Scientists at the Department of Energy's Oak Ridge National Laboratory have created a miniaturized environment to study the ecosystem around poplar tree roots for insights into plant health and soil carbon sequestration.

24 Aug 2022

Research reveals the secrets of photosynthesis in the shade

Plants and algae use green-tinted chlorophyll to convert high-energy sunlight into food via photosynthesis.

10 Aug 2022

UCLA researchers receive NIH award to develop next-generation versions of miniature microscope

The UCLA creators of a miniature microscope that can be mounted on the heads of lab animals to provide an invaluable view into the brain's inner workings have received a $4 million grant from the National Institutes of Health to develop next-generation versions of their "miniscope."

9 Aug 2022

Scientists develop microscopy technology that observes how new neurons struggle to reach their developmental destination

With organoids to model early growth, scientists employed a developing microscopy technology to observe that new neurons find it hard to reach their developmental goal.

From Massachusetts Institute of Technology (MIT) 1 Aug 2022

Scientists discover the first structures of angiotensin-converting enzyme using cryo-EM

University of Cape Town (UCT) researchers have used cryo-electron microscopy to identify the first complete structures of the human angiotensin-converting enzyme (ACE) (cryo-EM). A protein that controls blood pressure, ACE, is essential for maintaining good heart health.

14 Jul 2022

Researchers use new technique to examine the composition of cell walls from young poplar trees

To optimize biomaterials for reliable, cost-effective paper production, building construction, and biofuel development, researchers often study the structure of plant cells using techniques such as freezing plant samples or placing them in a vacuum.

8 Jun 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

Scientists get a clearer and more accurate image of proteins

Proteins are among the most significant and diverse biomolecules found in living organisms. These strings of amino acids, which take on complex 3-dimensional structures, are required for tissue growth and maintenance, the activation of thousands of biochemical events, and the immune system’s defense against invaders.

3 May 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022