Histology & Microscopy

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Novel approach accelerates cancer biomarker detection in point-of-care scenarios

The detection and quantification of cancer-associated molecular biomarkers in body fluids, or liquid biopsies, prove minimally invasive in early cancer diagnostics.

31 Jan 2022

Researchers use cryo-EM to rapidly characterize antibodies at atomic level

Scripps Research scientists have found a mechanism that may be able to bypass one of the critical steps in current vaccine production.

24 Jan 2022

Label-free device enables in-situ tracking of cell development and maturation

The biological intracellular microenvironment is diverse, consisting of several cell compartments and intracellular components.

20 Jan 2022

Researchers discover a key mechanism used by Zika virus to evade cell’s antiviral response

The world knows SARS-CoV-2 intimately now, but there are more than 200 virus species capable of infecting humans and causing disease.

19 Jan 2022

First molecular images of enzyme may help solve the mystery cause of hereditary neurodegenerative diseases

WEHI researchers have produced the first molecular images of an enzyme that controls proteins to signal and communicate with each other in human cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 13 Jan 2022

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

12 Jan 2022

Fluidlab; Combining Cell Counting and Spectrometry to Improve Fluid Analysis

In this interview, we speak to David Heinz from anvajo about their fluidlab technology that combines cell counting and spectrometry to improve fluid analysis.

From anvajo 11 Jan 2022

Scientists shed light on mechanisms responsible for maturation of the splicing machinery

Alternative Splicing is an extraordinarily complex process that requires the coordinated action of multiple proteins, each specialized in very specific functions. These proteins are assembled and matured, forming a kind of consortium of proteins that perform these gene reading functions.

31 Dec 2021

Researchers grow intestinal organoids to study why bats infected with viruses do not succumb to diseases

Experiments attempting to explain why bats can be infected with many viruses at a time without succumbing to diseases such as COVID-19-;knowledge that could help us to reduce the threat to humans of infectious disease-;have struggled until now with the fact that live wild bats make poor research subjects.

30 Dec 2021

Novel tool provides an unprecedented view of brain cell activity

To decipher the mysteries behind memory and learning, researchers from Johns Hopkins Medicine developed a system to trace millions of connections amongst brain cells in mice.

22 Dec 2021

Researchers develop new method to detect the onset of blood damage at sublethal stage

Red blood cells (RBCs) or erythrocytes are constantly exposed to a "shearing stress" during their circulation in the body. This stress is usually mild and the RBCs are flexible enough to accommodate shape changes in response to it.

17 Dec 2021

Detachable head-mounted photoacoustic microscope images brain activity in mice

Scientists recently generated the first detachable head-mounted photoacoustic microscope for imaging brain activity in freely roaming mice.

13 Dec 2021

First molecular structure of TDP-43 could pave the way for new ALS therapies

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Highly optimized X-ray process delivers high-resolution 3D images of cells

Viral pathogens such as the SARS-CoV-2 coronavirus alter the interior structure of the cells they infect.

8 Dec 2021

Scientists unravel the structure of octopus-like Lassa viral polymerase

Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or faeces of Mastomys rats.

7 Dec 2021

New two-photon microscope provides unprecedented brain-imaging ability

Advancing our understanding of the human brain will require new insights into how neural circuitry works in mammals, including laboratory mice.

3 Dec 2021

Experts analyze key protein complexes involved in DNA replication and repair

Cryogenic electron microscopy (cryo-EM) allows scientists to investigate the assembly of DNA replication machinery where DNA is damaged.

25 Nov 2021

Study discovers new species of green microalga in São Paulo

A group led by researchers affiliated with the Phycology Laboratory at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, have discovered a new species of green microalga in a reservoir located in the northwest of the state.

24 Nov 2021

Scientists develop advanced imaging technique to analyze oxygenation within bone tissue

Without doubt, the future of life sciences is sure to have technology that can measure biological parameters real-time in living organisms.

23 Nov 2021

New technique for label-free identification of microplastics in human cells

The research is supported by the Russian Science Foundation (grant 21-73-00097).