Histology & Microscopy

RSS

Cryo-EM Uncovers How Tiny Protein Enzyme Precisely Trims tRNA

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the right amino acids to ribosomes, the cell's protein-making factories.

8 Jul 2025

Scientists Discover Unique Bacterial Protein That Traps Membrane Lipids

Scientists have identified a new type of protein in bacteria that could change our understanding of how these organisms interact with their environments.

8 Jul 2025

Ireland’s First BioBrillouin Microscope Arrives at Trinity College Dublin

Trinity College Dublin now has Ireland's first and only BioBrillouin microscope, which will enable researchers to make giant strides in the fields of inflammation, cancer, developmental biology and biomedical materials, among others.

5 Jul 2025

Understanding the Bacterial Propeller Architecture Offers Hope Against Antibiotic Resistance

Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.

2 Jul 2025

ColdBrew Enhances Accuracy of Protein Water Mapping for Drug Design

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers function.

30 Jun 2025

Fluorescent Molecules Offer Unprecedented Insight into Cell Structures

Scientists have long used fluorescent dyes—which emit light—to research cell structures and activities.

25 Jun 2025

Researchers Use Biology to Convert Human Urine into a Valuable Product

Researchers from the Lawrence Berkeley National Laboratory (Berkeley Lab), UC Irvine, and the University of Illinois Urbana-Champaign (UIUC), have used biology to convert human urine into a valuable product.

24 Jun 2025

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

Single-cell RNA sequencing provides scientists with important information about gene expression in health and disease.

18 Jun 2025

Bacteria Use Harpoon-Like Weapons to Kill and Eat Their Neighbors

Bacteria are microscopic murderers. We've long known that bacteria kill each other, it's part of microbial life.

17 Jun 2025

Cryo-EM Structures Reveal How IVD Mutations Cause Isovaleric Acidemia

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA.

10 Jun 2025

Three-Dimensionally Reconstructed Kidney Glomerulus Simulates Structural and Functional Characteristics In Vitro

A 3D engineered kidney glomerulus model replicates structural and mechanical features of the glomerular filtration barrier, enabling the study of podocyte-related diseases and drug screening with improved physiological relevance.

2 Jun 2025

New Insights into the Molecular Fight or Flight Reset

Being cut off in traffic, giving a presentation or missing a meal can all trigger a suite of physiological changes that allows the body to react swiftly to stress or starvation.

30 May 2025

Study Identifies SMARCB1 and MEOX2 Genes as Growth Regulators of Lung Cancers

A Cancer Gene Therapy study reveals that MEOX2 promotes lung cancer progression while SMARCB1 acts as a tumor suppressor, influencing EGFR expression and response to tyrosine kinase inhibitors.

30 May 2025

Scientists Develop Method to Overcome Key Limitations of Cryo-EM

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveals their inner structures.

22 May 2025

Cell Painting Technology Reveals Potential Cancer-Fighting Flavonoids

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

21 May 2025

Microscopy Study Uncovers Dynamic Brain Remodeling During Hormonal Cycles

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles.

14 May 2025

Cryo-EM Reveals Protein-Free RNA Structures in Bacterial Cells

Cryogenic electron microscopy showed for the first time that large RNA complexes can assemble without the help of proteins, expanding our understanding of RNA folding and function.

10 May 2025

New Neural Circuit Discovery Explains Precision Steering in Fruit Flies

When a fruit fly is navigating straight forward at high speed, why does it know that it's not straying off course? Because as long as the fly moves directly forward, the visual scene shifts from front to back in a near-perfect mirror image across both retinas – generating, in other words, a symmetrical visual motion pattern.

2 May 2025

Unraveling the Interaction Between Mitochondrial Proteins HAX1 and CLPB

A recent study published in Magnetic Resonance Letters has revealed for the first time the interaction mechanism between the mitochondrial proteins HAX1 and CLPB, filling the research gap between these two key proteins in the field of structural dynamics and functional association.

10 Apr 2025

Scientists Unveil Dynamic Structure of Vision-Linked Protein RBP3

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought.

8 Apr 2025