Histology & Microscopy

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Neuron-Like Telocytes Directly Connect to Stem Cells in the Intestine

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut.

24 Jul 2025

Misfolded Proteins in Mitochondria Linked to Type 2 Diabetes

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.

23 Jul 2025

MiROM Uses Infrared Light to Detect Protein Changes in Single Cells

MiROM identifies proteins by using mid-infrared light to detect molecular vibrations – essentially the natural "dance" of molecules within protein structures.

16 Jul 2025

Breakthrough Imaging Technique Reveals Mitochondrial Dynamics in Living Tissues

In this study, researcher developed a new imaging approach that combines two powerful techniques to solve this problem. First, a special type of microscope called a two-photon microscope is used, which can look deep into live tissues with minimal damage.

14 Jul 2025

New Microchip Maps Antibody Responses Using Just a Drop of Blood

A new microchip invented by Scripps Research scientists can reveal how a person's antibodies interact with viruses-using just a drop of blood.

14 Jul 2025

Bacteria Show Unexpected Flexibility in Building Their Cell Walls

Closely related bacterial species use different strategies to build their cell walls, an international team of scientists led by Université de Montréal microbiology professor Yves Brun has found.

10 Jul 2025

Cryo-EM Uncovers How Tiny Protein Enzyme Precisely Trims tRNA

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the right amino acids to ribosomes, the cell's protein-making factories.

8 Jul 2025

Scientists Discover Unique Bacterial Protein That Traps Membrane Lipids

Scientists have identified a new type of protein in bacteria that could change our understanding of how these organisms interact with their environments.

8 Jul 2025

Ireland’s First BioBrillouin Microscope Arrives at Trinity College Dublin

Trinity College Dublin now has Ireland's first and only BioBrillouin microscope, which will enable researchers to make giant strides in the fields of inflammation, cancer, developmental biology and biomedical materials, among others.

5 Jul 2025

Understanding the Bacterial Propeller Architecture Offers Hope Against Antibiotic Resistance

Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.

2 Jul 2025

ColdBrew Enhances Accuracy of Protein Water Mapping for Drug Design

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers function.

30 Jun 2025

Fluorescent Molecules Offer Unprecedented Insight into Cell Structures

Scientists have long used fluorescent dyes—which emit light—to research cell structures and activities.

25 Jun 2025

Researchers Use Biology to Convert Human Urine into a Valuable Product

Researchers from the Lawrence Berkeley National Laboratory (Berkeley Lab), UC Irvine, and the University of Illinois Urbana-Champaign (UIUC), have used biology to convert human urine into a valuable product.

24 Jun 2025

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

Single-cell RNA sequencing provides scientists with important information about gene expression in health and disease.

18 Jun 2025

Bacteria Use Harpoon-Like Weapons to Kill and Eat Their Neighbors

Bacteria are microscopic murderers. We've long known that bacteria kill each other, it's part of microbial life.

17 Jun 2025

Cryo-EM Structures Reveal How IVD Mutations Cause Isovaleric Acidemia

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA.

10 Jun 2025

Three-Dimensionally Reconstructed Kidney Glomerulus Simulates Structural and Functional Characteristics In Vitro

A 3D engineered kidney glomerulus model replicates structural and mechanical features of the glomerular filtration barrier, enabling the study of podocyte-related diseases and drug screening with improved physiological relevance.

2 Jun 2025

New Insights into the Molecular Fight or Flight Reset

Being cut off in traffic, giving a presentation or missing a meal can all trigger a suite of physiological changes that allows the body to react swiftly to stress or starvation.

30 May 2025

Study Identifies SMARCB1 and MEOX2 Genes as Growth Regulators of Lung Cancers

A Cancer Gene Therapy study reveals that MEOX2 promotes lung cancer progression while SMARCB1 acts as a tumor suppressor, influencing EGFR expression and response to tyrosine kinase inhibitors.

30 May 2025