Histology & Microscopy

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How Comamonas Bacteria Transform Plastic Waste into Food

Researchers have long observed that a common family of environmental bacteria, Comamonadacae, grow on plastics littered throughout urban rivers and wastewater systems.

7 Oct 2024

Mapping the Complex Structure and Function of CRISPR-Cas Protein Scissors

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions.

3 Oct 2024

Scientists Successfully Map the Entire Fruit Fly Brain

A team of scientists supported by the National Institutes of Health (NIH)'s The BRAIN Initiative, including Davi Bock, Ph.D., Associate Professor of Neurological Sciences at UVM's Robert Larner, M.D. College of Medicine, recently made a substantial advancement in neurobiological research by successfully mapping the entire brain of Drosophila melanogaster, more commonly known as the fruit fly.

3 Oct 2024

Structural Discovery of Fanzor Proteins Offers New Directions in Genome Engineering

A revolution in biomedicine is currently underway, driven by the application of genome engineering tools such as the prokaryotic CRISPR-Cas9.

3 Oct 2024

Breakthrough Discovery on How TGF-Beta Communicates in Cells

Scientists discover how TGF-Beta, a crucial protein in development and cancer, sends its message even while tethered to the cell membrane.

17 Sep 2024

CHIEF Model Transforms Cancer Evaluation with Enhanced Generalizability Across Diverse Histopathology Samples

The CHIEF model revolutionizes cancer diagnosis, leveraging histopathological imaging to predict tumor origins and survival outcomes with exceptional accuracy.

16 Sep 2024

New Protein Identified in Ferns Reveals Role in Plant Gender and Stem Cell Control

Purdue University plant scientists have identified a protein that plays a previously unknown role in controlling cell differentiation and determining gender in vascular plants, using a fern model.

13 Sep 2024

Research Uncovers Unique Cell Division Mechanism in Dental Plaque Bacteria

One of the most diverse ecosystems on the planet is closer than you think -; right inside your mouth. Your mouth is a thriving ecosystem of more than 500 different species of bacteria living in distinct, structured communities called biofilms.

3 Sep 2024

High-Speed Atomic Force Microscopy Reveals Cofilin Binding Patterns in Actin Filaments

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin.

29 Aug 2024

EMBL Researchers Develop Novel Photoacoustic Probes to Monitor Brain Activity

To understand the brain better, we need new methods to observe its activity.

28 Aug 2024

Computational Modeling and Experimental Findings on Nucleosome Constraining in Mitosis

Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells. Despite recent advances in cell biology, the mechanism by which DNA condenses during mitosis is still poorly understood. Researchers recently tracked small stretches of DNA wound around histone proteins, called nucleosomes, to better characterize nucleosome behavior during cell division.

27 Aug 2024

Cryo-EM Reveals CDCA7's Hemimethylation Sensing in Nucleosome Core Particles

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism. Disruptions in the standard DNA methylation patterns can lead to immunodeficiency and diseases such as cancer.

27 Aug 2024

New Imaging Technique Offers Clearer View of Brain Function

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue than traditional two-photon microscopy, the new approach could provide a clearer view of how neurons communicate in real time, leading to new insights into brain function and neurological diseases.

16 Aug 2024

New ProDOL Technique Revolutionizes Protein Counting in Living Cells

Scientists have developed a new way of counting labeled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.

12 Aug 2024

New Microscope Peels Back Layers of Cellular Mystery

What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers from the Universities of Göttingen and Oxford, in collaboration with the University Medical Center Göttingen (UMG), have succeeded in developing a microscope with resolutions better than five nanometers (five billionths of a meter). This is roughly equivalent to the width of a hair split into 10,000 strands. Their new method was published in Nature Photonics.

9 Aug 2024

Histology & Microscopy

How Comamonas Bacteria Transform Plastic Waste into Food

Mapping the Complex Structure and Function of CRISPR-Cas Protein Scissors

Scientists Successfully Map the Entire Fruit Fly Brain

Structural Discovery of Fanzor Proteins Offers New Directions in Genome Engineering

Breakthrough Discovery on How TGF-Beta Communicates in Cells

CHIEF Model Transforms Cancer Evaluation with Enhanced Generalizability Across Diverse Histopathology Samples

New Protein Identified in Ferns Reveals Role in Plant Gender and Stem Cell Control

Research Uncovers Unique Cell Division Mechanism in Dental Plaque Bacteria

High-Speed Atomic Force Microscopy Reveals Cofilin Binding Patterns in Actin Filaments

EMBL Researchers Develop Novel Photoacoustic Probes to Monitor Brain Activity

Computational Modeling and Experimental Findings on Nucleosome Constraining in Mitosis

Cryo-EM Reveals CDCA7's Hemimethylation Sensing in Nucleosome Core Particles

New Imaging Technique Offers Clearer View of Brain Function

New ProDOL Technique Revolutionizes Protein Counting in Living Cells

New Microscope Peels Back Layers of Cellular Mystery

Discovery of Novel Macrophage Population Offers Hope for Lung Repair Post-Viral Infection

Innovative Nanosensing Method Promises Safer Gene Therapy with Improved AAV Vector Quality

Novel Microscopy Method Revolutionizes Imaging with Reduced Radiation and Faster Results

Probing Plasma Membrane Dynamics with Cryo-Electron Microscopy

Novel ATP Imaging System Reveals Insights into Kidney Energy Metabolism

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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