Microbiology

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Effective encoding strategy streamlines the handling and storage of single-cell data

Single-cell analysis is an effective biomedical technique used to identify unusual cell populations, monitor cell development and differentiation, comprehend disease causes, and design individualized therapies, but it generates massive amounts of data that can be challenging to handle.

23 Mar 2023

Identifying biomarkers that help treat fatty liver patients with a personalized diet

Recent research from the University of Jyväskylä contrasted the gut microbiota and gut-derived metabolites of healthy controls and fatty liver patients. The findings show that some microbial metabolites are linked to liver fat content.

23 Mar 2023

Using viruses to fight antibiotic-resistant "superbugs"

The Centers for Disease Control and Prevention warns that the increase in cases of the drug-resistant bacterial infection Shigella could be a predictor of what's to come for other bacteria.

22 Mar 2023

CABBI/GLBRC researchers peer into the complexities of life on a leaf

"Have you ever wondered about life on a leaf?" Great Lakes Bioenergy Research Center (GLBRC) researcher Ashley Shade asks a simple question, but it's one well worth investigation.

22 Mar 2023

Stickiness of influenza virus may determine the frequency of co-infection

Influenza viruses have an enormous impact in the U.S., with an estimated 25 million illnesses and 18,000 deaths in the 2022-23 flu season alone.

21 Mar 2023

Novel mechanism by which bacteria colonize the gut identified

A new mechanism by which “good” bacteria colonize the gut was unraveled by scientists at Yale University. The finding could aid spur the development of new probiotic therapies.

20 Mar 2023

Common commensal gut bacterium uses phase separation of Rho factor to thrive in the mammalian gut

The common commensal gut bacterium Bacteroides thetaiotaomicron uses phase separation of the transcription termination factor Rho to colonize and thrive in the mammalian gut, according to a new study in mice.

17 Mar 2023

Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually.

17 Mar 2023

Emergence and spread of a deadly fungus among African amphibians

For the past few years, how a virus triggered a global pandemic has dominated conversations. Now, thanks to the TV show "The Last of Us" (about an apocalypse triggered by brain-eating 'shrooms), fungi have infected popular culture.

16 Mar 2023

Influence of molecular component of caffeine on gut health

Certain microbes are considered to play a role in the development of inflammatory disorders such as inflammatory bowel disease (IBD).

16 Mar 2023

Deciphering the mechanisms used by a fungus to increase iron acquisition

The University of Cordoba discovered how the entomopathogenic fungus Metarhiziumbrunneum increases iron acquisition in melon and cucumber.

15 Mar 2023

Study evaluates the risk posed by the fungus Bd to amphibians across the continent of Africa

Mass fungus infections that drive populations worldwide to near-collapse don't just occur in science fiction. Chytridiomycosis, the worst vertebrate disease in recorded history, has already wiped out hundreds of species of amphibians around the world. Due to a large part to this fungal disease, 41% of amphibians are currently threatened with extinction. Only species living in Africa seemed to have been relatively spared from the scourge of chytridiomycosis – at least so far.

15 Mar 2023

Transforming the natural mineral shells of algae into functional perovskites

Perovskites are materials that are increasingly popular for a wide range of applications because of their remarkable electrical, optical, and photonic properties.

14 Mar 2023

Gut microbiome may modulate the efficacy of CAR-T cell cancer immunotherapy

Scientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the USA, have found that the gut microbiome may modulate the efficacy of CAR-T cellular immunotherapy CAR-T cells in patients with B cell lymphomas.

14 Mar 2023

Bile salt hydrolase cocktails may offer a new approach to inhibit C. diff colonization

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

14 Mar 2023

New framework to identify possible viral hazards to human health

The majority of what scientists know about viruses in animals comes from the list of nucleotides that constitute their genomic sequence, which, although useful, provides relatively few signals about a virus’ propensity to infect people.

14 Mar 2023

Novel technology easily detects active Mycobacterium tuberculosis infection antibodies

A team of faculty from Wayne State University has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies.

14 Mar 2023

Analyzing the antimicrobial resistance profile of the main agent of urinary tract infections

The human intestine is an environment inhabited by many bacteria and other microorganisms collectively known as the gut microbiome, gut microbiota or intestinal flora. In most people, it contributes to wellness. A healthy gut indicates a stronger immune system, improved metabolism, and a healthy brain and heart, among other functions.

14 Mar 2023

Developing new therapies that leverage the host immune system

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis. A relative, Yersinia pseudotuberculosis, causes gastrointestinal illness and is less deadly but naturally infects both mice and humans, making it a useful model for studying its interactions with the immune system.

14 Mar 2023

Understanding the relationship between gut microbiome and CAR T-cell therapy response

Microorganisms live in or on almost every part of the human body and play an important role in the regulation of normal human processes. As a result, changes in the number or type of microorganisms, also known as the microbiome, can contribute to disease and altered responses to therapy, including cancer treatment.

14 Mar 2023

Microbiology

Effective encoding strategy streamlines the handling and storage of single-cell data

Identifying biomarkers that help treat fatty liver patients with a personalized diet

Using viruses to fight antibiotic-resistant "superbugs"

CABBI/GLBRC researchers peer into the complexities of life on a leaf

Stickiness of influenza virus may determine the frequency of co-infection

Novel mechanism by which bacteria colonize the gut identified

Common commensal gut bacterium uses phase separation of Rho factor to thrive in the mammalian gut

Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Emergence and spread of a deadly fungus among African amphibians

Influence of molecular component of caffeine on gut health

Deciphering the mechanisms used by a fungus to increase iron acquisition

Study evaluates the risk posed by the fungus Bd to amphibians across the continent of Africa

Transforming the natural mineral shells of algae into functional perovskites

Gut microbiome may modulate the efficacy of CAR-T cell cancer immunotherapy

Bile salt hydrolase cocktails may offer a new approach to inhibit C. diff colonization

New framework to identify possible viral hazards to human health

Novel technology easily detects active Mycobacterium tuberculosis infection antibodies

Analyzing the antimicrobial resistance profile of the main agent of urinary tract infections

Developing new therapies that leverage the host immune system

Understanding the relationship between gut microbiome and CAR T-cell therapy response

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